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Bulimia nervosa

MedGen UID:
389218
•Concept ID:
C2267227
•
Mental or Behavioral Dysfunction
Synonyms: Bulimia Nervosa; Nervosa, Bulimia
SNOMED CT: BN - Bulimia nervosa (78004001); Bulimia nervosa (78004001)
 
Monarch Initiative: MONDO:0005452

Definition

A disorder characterized by recurrent episodes of binge-eating over which the individual feels a lack of control; these episodes of binge-eating are followed by recurrent compensatory behavior to prevent weight gain, usually self-induced vomiting. In addition, self-evaluation is unduly influenced by body image. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBulimia nervosa

Professional guidelines

PubMed

Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses.
Monteleone AM, Pellegrino F, Croatto G, Carfagno M, Hilbert A, Treasure J, Wade T, Bulik CM, Zipfel S, Hay P, Schmidt U, Castellini G, Favaro A, Fernandez-Aranda F, Il Shin J, Voderholzer U, Ricca V, Moretti D, Busatta D, Abbate-Daga G, Ciullini F, Cascino G, Monaco F, Correll CU, Solmi M
Neurosci Biobehav Rev 2022 Nov;142:104857. Epub 2022 Sep 6 doi: 10.1016/j.neubiorev.2022.104857. PMID: 36084848Free PMC Article
Psychopharmacologic Management of Eating Disorders.
Muratore AF, Attia E
Curr Psychiatry Rep 2022 Jul;24(7):345-351. Epub 2022 May 16 doi: 10.1007/s11920-022-01340-5. PMID: 35576089Free PMC Article
Initial evaluation, diagnosis, and treatment of anorexia nervosa and bulimia nervosa.
Harrington BC, Jimerson M, Haxton C, Jimerson DC
Am Fam Physician 2015 Jan 1;91(1):46-52. PMID: 25591200

Curated

UK NICE Guideline NG69, Eating disorders: recognition and treatment, 2020

Recent clinical studies

Etiology

Incidence, prevalence and mortality of anorexia nervosa and bulimia nervosa.
van Eeden AE, van Hoeken D, Hoek HW
Curr Opin Psychiatry 2021 Nov 1;34(6):515-524. doi: 10.1097/YCO.0000000000000739. PMID: 34419970Free PMC Article
Medical complications of bulimia nervosa.
Nitsch A, Dlugosz H, Gibson D, Mehler PS
Cleve Clin J Med 2021 Jun 2;88(6):333-343. doi: 10.3949/ccjm.88a.20168. PMID: 34078617
Genetics of Eating Disorders: What the Clinician Needs to Know.
Bulik CM, Blake L, Austin J
Psychiatr Clin North Am 2019 Mar;42(1):59-73. doi: 10.1016/j.psc.2018.10.007. PMID: 30704640
Medical Complications in Anorexia and Bulimia Nervosa.
Gravina G, Milano W, Nebbiai G, Piccione C, Capasso A
Endocr Metab Immune Disord Drug Targets 2018;18(5):477-488. doi: 10.2174/1871530318666180531094508. PMID: 29848283
Bulimia Nervosa/Purging Disorder.
Castillo M, Weiselberg E
Curr Probl Pediatr Adolesc Health Care 2017 Apr;47(4):85-94. doi: 10.1016/j.cppeds.2017.02.004. PMID: 28532966

Diagnosis

Eating Disorders in the Adolescent Patient.
Ranalli DN, Studen-Pavlovich D
Dent Clin North Am 2021 Oct;65(4):689-703. Epub 2021 Aug 2 doi: 10.1016/j.cden.2021.06.009. PMID: 34503661
Current approach to eating disorders: a clinical update.
Hay P
Intern Med J 2020 Jan;50(1):24-29. doi: 10.1111/imj.14691. PMID: 31943622Free PMC Article
Recent Research on Bulimia Nervosa.
Wade TD
Psychiatr Clin North Am 2019 Mar;42(1):21-32. Epub 2018 Dec 3 doi: 10.1016/j.psc.2018.10.002. PMID: 30704637
Bulimia Nervosa/Purging Disorder.
Castillo M, Weiselberg E
Curr Probl Pediatr Adolesc Health Care 2017 Apr;47(4):85-94. doi: 10.1016/j.cppeds.2017.02.004. PMID: 28532966
Initial evaluation, diagnosis, and treatment of anorexia nervosa and bulimia nervosa.
Harrington BC, Jimerson M, Haxton C, Jimerson DC
Am Fam Physician 2015 Jan 1;91(1):46-52. PMID: 25591200

Therapy

Is physical exercise and dietary therapy a feasible alternative to cognitive behavior therapy in treatment of eating disorders? A randomized controlled trial of two group therapies.
Mathisen TF, Rosenvinge JH, Friborg O, Vrabel K, Bratland-Sanda S, Pettersen G, Sundgot-Borgen J
Int J Eat Disord 2020 Apr;53(4):574-585. Epub 2020 Jan 16 doi: 10.1002/eat.23228. PMID: 31944339Free PMC Article
The efficacy of cognitive-behavioral therapy for eating disorders: A systematic review and meta-analysis.
Linardon J, Wade TD, de la Piedad Garcia X, Brennan L
J Consult Clin Psychol 2017 Nov;85(11):1080-1094. doi: 10.1037/ccp0000245. PMID: 29083223
Effectiveness of psychosocial interventions in eating disorders: an overview of Cochrane systematic reviews.
Costa MB, Melnik T
Einstein (Sao Paulo) 2016 Apr-Jun;14(2):235-77. doi: 10.1590/S1679-45082016RW3120. PMID: 27462898Free PMC Article
Randomized Clinical Trial of Family-Based Treatment and Cognitive-Behavioral Therapy for Adolescent Bulimia Nervosa.
Le Grange D, Lock J, Agras WS, Bryson SW, Jo B
J Am Acad Child Adolesc Psychiatry 2015 Nov;54(11):886-94.e2. Epub 2015 Sep 2 doi: 10.1016/j.jaac.2015.08.008. PMID: 26506579Free PMC Article
A systematic review of physical therapy interventions for patients with anorexia and bulemia nervosa.
Vancampfort D, Vanderlinden J, De Hert M, Soundy A, Adámkova M, Skjaerven LH, Catalán-Matamoros D, Lundvik Gyllensten A, Gómez-Conesa A, Probst M
Disabil Rehabil 2014;36(8):628-34. Epub 2013 Jul 4 doi: 10.3109/09638288.2013.808271. PMID: 23826882

Prognosis

Incidence, prevalence and mortality of anorexia nervosa and bulimia nervosa.
van Eeden AE, van Hoeken D, Hoek HW
Curr Opin Psychiatry 2021 Nov 1;34(6):515-524. doi: 10.1097/YCO.0000000000000739. PMID: 34419970Free PMC Article
Recovery From Anorexia Nervosa and Bulimia Nervosa at 22-Year Follow-Up.
Eddy KT, Tabri N, Thomas JJ, Murray HB, Keshaviah A, Hastings E, Edkins K, Krishna M, Herzog DB, Keel PK, Franko DL
J Clin Psychiatry 2017 Feb;78(2):184-189. doi: 10.4088/JCP.15m10393. PMID: 28002660Free PMC Article
Risk factors that predict future onset of each DSM-5 eating disorder: Predictive specificity in high-risk adolescent females.
Stice E, Gau JM, Rohde P, Shaw H
J Abnorm Psychol 2017 Jan;126(1):38-51. Epub 2016 Oct 6 doi: 10.1037/abn0000219. PMID: 27709979Free PMC Article
Epidemiology, course, and outcome of eating disorders.
Smink FR, van Hoeken D, Hoek HW
Curr Opin Psychiatry 2013 Nov;26(6):543-8. doi: 10.1097/YCO.0b013e328365a24f. PMID: 24060914
Epidemiology of eating disorders: incidence, prevalence and mortality rates.
Smink FR, van Hoeken D, Hoek HW
Curr Psychiatry Rep 2012 Aug;14(4):406-14. doi: 10.1007/s11920-012-0282-y. PMID: 22644309Free PMC Article

Clinical prediction guides

Prevalence of Eating Disorders and Their Association with Social Media Addiction among Youths.
Mushtaq T, Ashraf S, Hameed H, Irfan A, Shahid M, Kanwal R, Aslam MA, Shahid H, Koh-E-Noor, Shazly GA, Khan MA, Jardan YAB
Nutrients 2023 Nov 5;15(21) doi: 10.3390/nu15214687. PMID: 37960340Free PMC Article
Eating disorders in the era of the COVID-19 pandemic.
Gonidakis F
Psychiatriki 2022 Dec 7;33(4):267-270. Epub 2022 Nov 17 doi: 10.22365/jpsych.2022.096. PMID: 36436215
Personality Variables and Eating Pathology.
Wagner AF, Vitousek KM
Psychiatr Clin North Am 2019 Mar;42(1):105-119. Epub 2018 Dec 17 doi: 10.1016/j.psc.2018.10.012. PMID: 30704632
A systematic review of physical therapy interventions for patients with anorexia and bulemia nervosa.
Vancampfort D, Vanderlinden J, De Hert M, Soundy A, Adámkova M, Skjaerven LH, Catalán-Matamoros D, Lundvik Gyllensten A, Gómez-Conesa A, Probst M
Disabil Rehabil 2014;36(8):628-34. Epub 2013 Jul 4 doi: 10.3109/09638288.2013.808271. PMID: 23826882
Bulimia nervosa.
Hay PJ, Claudino AM
BMJ Clin Evid 2010 Jul 19;2010 PMID: 21418667Free PMC Article

Recent systematic reviews

A systematic review comparing atypical anorexia nervosa and anorexia nervosa.
Walsh BT, Hagan KE, Lockwood C
Int J Eat Disord 2023 Apr;56(4):798-820. Epub 2022 Dec 12 doi: 10.1002/eat.23856. PMID: 36508318
The impact of the COVID-19 pandemic on eating disorders: A systematic review.
J Devoe D, Han A, Anderson A, Katzman DK, Patten SB, Soumbasis A, Flanagan J, Paslakis G, Vyver E, Marcoux G, Dimitropoulos G
Int J Eat Disord 2023 Jan;56(1):5-25. Epub 2022 Apr 5 doi: 10.1002/eat.23704. PMID: 35384016Free PMC Article
Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses.
Monteleone AM, Pellegrino F, Croatto G, Carfagno M, Hilbert A, Treasure J, Wade T, Bulik CM, Zipfel S, Hay P, Schmidt U, Castellini G, Favaro A, Fernandez-Aranda F, Il Shin J, Voderholzer U, Ricca V, Moretti D, Busatta D, Abbate-Daga G, Ciullini F, Cascino G, Monaco F, Correll CU, Solmi M
Neurosci Biobehav Rev 2022 Nov;142:104857. Epub 2022 Sep 6 doi: 10.1016/j.neubiorev.2022.104857. PMID: 36084848Free PMC Article
Disentangling binge eating disorder and food addiction: a systematic review and meta-analysis.
di Giacomo E, Aliberti F, Pescatore F, Santorelli M, Pessina R, Placenti V, Colmegna F, Clerici M
Eat Weight Disord 2022 Aug;27(6):1963-1970. Epub 2022 Jan 18 doi: 10.1007/s40519-021-01354-7. PMID: 35041154Free PMC Article
Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article

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    Clinical resources

    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2020
      UK NICE Guideline NG69, Eating disorders: recognition and treatment, 2020

    Consumer resources

    Reviews

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