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Ischemic bowel disorder

MedGen UID:
412148
•Concept ID:
C2004435
•
Disease or Syndrome
Synonyms: Intestinal ischemia; Ischemic bowel disease
SNOMED CT: Vascular insufficiency of intestine (82196007); Ischemic bowel disease (82196007); Vascular insufficiency of the intestine (82196007); Intestinal ischemia (82196007); Ischemic disease of gut (82196007)
 
HPO: HP:0033404
Monarch Initiative: MONDO:0020675

Definition

Restriction of arterial blood supply to the intestine associated with insufficient oxygenation to support the metabolic requirements of the tissue. Acute intestinal ischemia can involve the small or large intestine, and usually presents with sudden severe non-specific abdominal pain. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIschemic bowel disorder

Professional guidelines

PubMed

Emergency Medicine Evaluation and Management of Small Bowel Obstruction: Evidence-Based Recommendations.
Long B, Robertson J, Koyfman A
J Emerg Med 2019 Feb;56(2):166-176. Epub 2018 Dec 6 doi: 10.1016/j.jemermed.2018.10.024. PMID: 30527563
Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group.
Ten Broek RPG, Krielen P, Di Saverio S, Coccolini F, Biffl WL, Ansaloni L, Velmahos GC, Sartelli M, Fraga GP, Kelly MD, Moore FA, Peitzman AB, Leppaniemi A, Moore EE, Jeekel J, Kluger Y, Sugrue M, Balogh ZJ, Bendinelli C, Civil I, Coimbra R, De Moya M, Ferrada P, Inaba K, Ivatury R, Latifi R, Kashuk JL, Kirkpatrick AW, Maier R, Rizoli S, Sakakushev B, Scalea T, Søreide K, Weber D, Wani I, Abu-Zidan FM, De'Angelis N, Piscioneri F, Galante JM, Catena F, van Goor H
World J Emerg Surg 2018;13:24. Epub 2018 Jun 19 doi: 10.1186/s13017-018-0185-2. PMID: 29946347Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845

Recent clinical studies

Etiology

An Update on Acute Mesenteric Ischemia.
Yu H, Kirkpatrick IDC
Can Assoc Radiol J 2023 Feb;74(1):160-171. Epub 2022 May 11 doi: 10.1177/08465371221094280. PMID: 35544414
Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery.
Bala M, Catena F, Kashuk J, De Simone B, Gomes CA, Weber D, Sartelli M, Coccolini F, Kluger Y, Abu-Zidan FM, Picetti E, Ansaloni L, Augustin G, Biffl WL, Ceresoli M, Chiara O, Chiarugi M, Coimbra R, Cui Y, Damaskos D, Di Saverio S, Galante JM, Khokha V, Kirkpatrick AW, Inaba K, Leppäniemi A, Litvin A, Peitzman AB, Shelat VG, Sugrue M, Tolonen M, Rizoli S, Sall I, Beka SG, Di Carlo I, Ten Broek R, Mircea C, Tebala G, Pisano M, van Goor H, Maier RV, Jeekel H, Civil I, Hecker A, Tan E, Soreide K, Lee MJ, Wani I, Bonavina L, Malangoni MA, Koike K, Velmahos GC, Fraga GP, Fette A, de'Angelis N, Balogh ZJ, Scalea TM, Sganga G, Kelly MD, Khan J, Stahel PF, Moore EE
World J Emerg Surg 2022 Oct 19;17(1):54. doi: 10.1186/s13017-022-00443-x. PMID: 36261857Free PMC Article
Colonoscopy-related colonic ischemia.
Sadalla S, Lisotti A, Fuccio L, Fusaroli P
World J Gastroenterol 2021 Nov 14;27(42):7299-7310. doi: 10.3748/wjg.v27.i42.7299. PMID: 34876790Free PMC Article
Ischemic bowel disease in 2021.
Ahmed M
World J Gastroenterol 2021 Aug 7;27(29):4746-4762. doi: 10.3748/wjg.v27.i29.4746. PMID: 34447224Free PMC Article
Abdominal angina.
Biolato M, Miele L, Gasbarrini G, Grieco A
Am J Med Sci 2009 Nov;338(5):389-95. doi: 10.1097/MAJ.0b013e3181a85c3b. PMID: 19794303

Diagnosis

An Update on Acute Mesenteric Ischemia.
Yu H, Kirkpatrick IDC
Can Assoc Radiol J 2023 Feb;74(1):160-171. Epub 2022 May 11 doi: 10.1177/08465371221094280. PMID: 35544414
Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery.
Bala M, Catena F, Kashuk J, De Simone B, Gomes CA, Weber D, Sartelli M, Coccolini F, Kluger Y, Abu-Zidan FM, Picetti E, Ansaloni L, Augustin G, Biffl WL, Ceresoli M, Chiara O, Chiarugi M, Coimbra R, Cui Y, Damaskos D, Di Saverio S, Galante JM, Khokha V, Kirkpatrick AW, Inaba K, Leppäniemi A, Litvin A, Peitzman AB, Shelat VG, Sugrue M, Tolonen M, Rizoli S, Sall I, Beka SG, Di Carlo I, Ten Broek R, Mircea C, Tebala G, Pisano M, van Goor H, Maier RV, Jeekel H, Civil I, Hecker A, Tan E, Soreide K, Lee MJ, Wani I, Bonavina L, Malangoni MA, Koike K, Velmahos GC, Fraga GP, Fette A, de'Angelis N, Balogh ZJ, Scalea TM, Sganga G, Kelly MD, Khan J, Stahel PF, Moore EE
World J Emerg Surg 2022 Oct 19;17(1):54. doi: 10.1186/s13017-022-00443-x. PMID: 36261857Free PMC Article
Colonoscopy-related colonic ischemia.
Sadalla S, Lisotti A, Fuccio L, Fusaroli P
World J Gastroenterol 2021 Nov 14;27(42):7299-7310. doi: 10.3748/wjg.v27.i42.7299. PMID: 34876790Free PMC Article
Ischemic bowel disease in 2021.
Ahmed M
World J Gastroenterol 2021 Aug 7;27(29):4746-4762. doi: 10.3748/wjg.v27.i29.4746. PMID: 34447224Free PMC Article
Acute mesenteric ischemia.
Sise MJ
Surg Clin North Am 2014 Feb;94(1):165-81. doi: 10.1016/j.suc.2013.10.012. PMID: 24267504

Therapy

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colonic Volvulus and Acute Colonic Pseudo-Obstruction.
Alavi K, Poylin V, Davids JS, Patel SV, Felder S, Valente MA, Paquette IM, Feingold DL; Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Dis Colon Rectum 2021 Sep 1;64(9):1046-1057. doi: 10.1097/DCR.0000000000002159. PMID: 34016826
Update on the management of intestinal failure.
Bharadwaj S, Tandon P, Rivas JM, Furman A, Moccia L, Ratliff A, Shatnawei A, Steiger E, Kirby DF
Cleve Clin J Med 2016 Nov;83(11):841-848. doi: 10.3949/ccjm.83a.15045. PMID: 27824535
Ischemic bowel syndromes.
Silva JA, White CJ
Prim Care 2013 Mar;40(1):153-67. Epub 2012 Dec 8 doi: 10.1016/j.pop.2012.11.007. PMID: 23402466
Low-dose colchicine for secondary prevention of cardiovascular disease.
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL
J Am Coll Cardiol 2013 Jan 29;61(4):404-410. Epub 2012 Dec 19 doi: 10.1016/j.jacc.2012.10.027. PMID: 23265346
Pseudomembranous colitis.
Price AB, Davies DR
J Clin Pathol 1977 Jan;30(1):1-12. doi: 10.1136/jcp.30.1.1. PMID: 838865Free PMC Article

Prognosis

Diagnostic methods and drug therapies in patients with ischemic colitis.
Xu Y, Xiong L, Li Y, Jiang X, Xiong Z
Int J Colorectal Dis 2021 Jan;36(1):47-56. Epub 2020 Sep 16 doi: 10.1007/s00384-020-03739-z. PMID: 32936393Free PMC Article
Marantic endocarditis.
Sánchez Quirós B, Ruiz López N, López Herrero R, Bartolomé Bartolomé C
Rev Esp Anestesiol Reanim (Engl Ed) 2020 Apr;67(4):208-211. Epub 2020 Mar 2 doi: 10.1016/j.redar.2020.01.005. PMID: 32139116
Acute mesenteric ischemia.
Sise MJ
Surg Clin North Am 2014 Feb;94(1):165-81. doi: 10.1016/j.suc.2013.10.012. PMID: 24267504
Low-dose colchicine for secondary prevention of cardiovascular disease.
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL
J Am Coll Cardiol 2013 Jan 29;61(4):404-410. Epub 2012 Dec 19 doi: 10.1016/j.jacc.2012.10.027. PMID: 23265346
Colonic ischemia.
Greenwald DA, Brandt LJ
J Clin Gastroenterol 1998 Sep;27(2):122-8. doi: 10.1097/00004836-199809000-00004. PMID: 9754772

Clinical prediction guides

Managing mesenteric vasculitis.
Angle JF, Nida BA, Matsumoto AH
Tech Vasc Interv Radiol 2015 Mar;18(1):38-42. Epub 2014 Dec 29 doi: 10.1053/j.tvir.2014.12.006. PMID: 25814202
Chronic mesenteric ischemia.
Wilkins LR, Stone JR
Tech Vasc Interv Radiol 2015 Mar;18(1):31-7. Epub 2014 Dec 29 doi: 10.1053/j.tvir.2014.12.005. PMID: 25814201
Acute mesenteric ischemia.
Stone JR, Wilkins LR
Tech Vasc Interv Radiol 2015 Mar;18(1):24-30. Epub 2014 Dec 29 doi: 10.1053/j.tvir.2014.12.004. PMID: 25814200
Low-dose colchicine for secondary prevention of cardiovascular disease.
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL
J Am Coll Cardiol 2013 Jan 29;61(4):404-410. Epub 2012 Dec 19 doi: 10.1016/j.jacc.2012.10.027. PMID: 23265346
Mesenteric venous thrombosis.
Harnik IG, Brandt LJ
Vasc Med 2010 Oct;15(5):407-18. doi: 10.1177/1358863X10379673. PMID: 20926500

Recent systematic reviews

Gut microbes in cerebrovascular diseases: Gut flora imbalance, potential impact mechanisms and promising treatment strategies.
Zou X, Wang L, Xiao L, Wang S, Zhang L
Front Immunol 2022;13:975921. Epub 2022 Oct 31 doi: 10.3389/fimmu.2022.975921. PMID: 36389714Free PMC Article
Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Jaén CR, Krist AH, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Tseng CW, Wong JB
JAMA 2022 Apr 26;327(16):1577-1584. doi: 10.1001/jama.2022.4983. PMID: 35471505
Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.
Acosta S, Salim S
Scand J Surg 2021 Jun;110(2):123-129. Epub 2020 Oct 29 doi: 10.1177/1457496920969084. PMID: 33118463Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013.
Kyu HH, Bachman VF, Alexander LT, Mumford JE, Afshin A, Estep K, Veerman JL, Delwiche K, Iannarone ML, Moyer ML, Cercy K, Vos T, Murray CJ, Forouzanfar MH
BMJ 2016 Aug 9;354:i3857. doi: 10.1136/bmj.i3857. PMID: 27510511Free PMC Article

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