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Labile hypertension due to being in a clinical environment

MedGen UID:
452336
•Concept ID:
C0262534
•
Disease or Syndrome
Synonyms: Clinic Hypertension, Isolated; Hypertension, Isolated Clinic; Hypertension, White Coat; Isolated Clinic Hypertension; Syndrome, White Coat; White Coat Hypertension; White Coat Syndrome
SNOMED CT: White coat hypertension (697930002); Labile hypertension due to being in a clinical environment (697930002)

Definition

Phenomenon where BLOOD PRESSURE readings are elevated only when taken in clinical settings. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLabile hypertension due to being in a clinical environment

Professional guidelines

PubMed

Resistant Hypertension in Dialysis: Epidemiology, Diagnosis, and Management.
Georgianos PI, Agarwal R
J Am Soc Nephrol 2024 Apr 1;35(4):505-514. Epub 2024 Jan 16 doi: 10.1681/ASN.0000000000000315. PMID: 38227447Free PMC Article
Hypertensive disorders of pregnancy: definition, management, and out-of-office blood pressure measurement.
Metoki H, Iwama N, Hamada H, Satoh M, Murakami T, Ishikuro M, Obara T
Hypertens Res 2022 Aug;45(8):1298-1309. Epub 2022 Jun 20 doi: 10.1038/s41440-022-00965-6. PMID: 35726086Free PMC Article
Treatment of Resistant and Refractory Hypertension.
Acelajado MC, Hughes ZH, Oparil S, Calhoun DA
Circ Res 2019 Mar 29;124(7):1061-1070. doi: 10.1161/CIRCRESAHA.118.312156. PMID: 30920924Free PMC Article

Recent clinical studies

Etiology

Hypertensive disorders of pregnancy: definition, management, and out-of-office blood pressure measurement.
Metoki H, Iwama N, Hamada H, Satoh M, Murakami T, Ishikuro M, Obara T
Hypertens Res 2022 Aug;45(8):1298-1309. Epub 2022 Jun 20 doi: 10.1038/s41440-022-00965-6. PMID: 35726086Free PMC Article
White-Coat Hypertension: Pathophysiological and Clinical Aspects: Excellence Award for Hypertension Research 2020.
Mancia G, Facchetti R, Bombelli M, Cuspidi C, Grassi G
Hypertension 2021 Dec;78(6):1677-1688. Epub 2021 Nov 10 doi: 10.1161/HYPERTENSIONAHA.121.16489. PMID: 34757765Free PMC Article
Resistant Hypertension: Novel Insights.
Lamirault G, Artifoni M, Daniel M, Barber-Chamoux N, Nantes University Hospital Working Group On Hypertension
Curr Hypertens Rev 2020;16(1):61-72. doi: 10.2174/1573402115666191011111402. PMID: 31622203
Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.
Cohen JB, Lotito MJ, Trivedi UK, Denker MG, Cohen DL, Townsend RR
Ann Intern Med 2019 Jun 18;170(12):853-862. Epub 2019 Jun 11 doi: 10.7326/M19-0223. PMID: 31181575Free PMC Article
Endothelial Dysfunction and Hypertension.
Konukoglu D, Uzun H
Adv Exp Med Biol 2017;956:511-540. doi: 10.1007/5584_2016_90. PMID: 28035582

Diagnosis

Resistant Hypertension in Dialysis: Epidemiology, Diagnosis, and Management.
Georgianos PI, Agarwal R
J Am Soc Nephrol 2024 Apr 1;35(4):505-514. Epub 2024 Jan 16 doi: 10.1681/ASN.0000000000000315. PMID: 38227447Free PMC Article
Hypertensive disorders of pregnancy: definition, management, and out-of-office blood pressure measurement.
Metoki H, Iwama N, Hamada H, Satoh M, Murakami T, Ishikuro M, Obara T
Hypertens Res 2022 Aug;45(8):1298-1309. Epub 2022 Jun 20 doi: 10.1038/s41440-022-00965-6. PMID: 35726086Free PMC Article
Hypertension trials update.
Al Ghorani H, Kulenthiran S, Lauder L, Böhm M, Mahfoud F
J Hum Hypertens 2021 May;35(5):398-409. Epub 2021 Jan 12 doi: 10.1038/s41371-020-00477-1. PMID: 33437020Free PMC Article
Resistant Hypertension: Novel Insights.
Lamirault G, Artifoni M, Daniel M, Barber-Chamoux N, Nantes University Hospital Working Group On Hypertension
Curr Hypertens Rev 2020;16(1):61-72. doi: 10.2174/1573402115666191011111402. PMID: 31622203
Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.
Cohen JB, Lotito MJ, Trivedi UK, Denker MG, Cohen DL, Townsend RR
Ann Intern Med 2019 Jun 18;170(12):853-862. Epub 2019 Jun 11 doi: 10.7326/M19-0223. PMID: 31181575Free PMC Article

Therapy

Ambulatory Blood Pressure Monitoring to Diagnose and Manage Hypertension.
Huang QF, Yang WY, Asayama K, Zhang ZY, Thijs L, Li Y, O'Brien E, Staessen JA
Hypertension 2021 Feb;77(2):254-264. Epub 2021 Jan 4 doi: 10.1161/HYPERTENSIONAHA.120.14591. PMID: 33390042Free PMC Article
Resistant Hypertension: Novel Insights.
Lamirault G, Artifoni M, Daniel M, Barber-Chamoux N, Nantes University Hospital Working Group On Hypertension
Curr Hypertens Rev 2020;16(1):61-72. doi: 10.2174/1573402115666191011111402. PMID: 31622203
Gender Differences in Hypertension.
Song JJ, Ma Z, Wang J, Chen LX, Zhong JC
J Cardiovasc Transl Res 2020 Feb;13(1):47-54. Epub 2019 May 1 doi: 10.1007/s12265-019-09888-z. PMID: 31044374
Endothelial Dysfunction and Hypertension.
Konukoglu D, Uzun H
Adv Exp Med Biol 2017;956:511-540. doi: 10.1007/5584_2016_90. PMID: 28035582
Hypertension in Chronic Kidney Disease.
Hamrahian SM, Falkner B
Adv Exp Med Biol 2017;956:307-325. doi: 10.1007/5584_2016_84. PMID: 27873228

Prognosis

Relationship between clinic and ambulatory blood pressure and mortality: an observational cohort study in 59 124 patients.
Staplin N, de la Sierra A, Ruilope LM, Emberson JR, Vinyoles E, Gorostidi M, Ruiz-Hurtado G, Segura J, Baigent C, Williams B
Lancet 2023 Jun 17;401(10393):2041-2050. Epub 2023 May 5 doi: 10.1016/S0140-6736(23)00733-X. PMID: 37156250
White-Coat Hypertension: Pathophysiological and Clinical Aspects: Excellence Award for Hypertension Research 2020.
Mancia G, Facchetti R, Bombelli M, Cuspidi C, Grassi G
Hypertension 2021 Dec;78(6):1677-1688. Epub 2021 Nov 10 doi: 10.1161/HYPERTENSIONAHA.121.16489. PMID: 34757765Free PMC Article
Hypertension trials update.
Al Ghorani H, Kulenthiran S, Lauder L, Böhm M, Mahfoud F
J Hum Hypertens 2021 May;35(5):398-409. Epub 2021 Jan 12 doi: 10.1038/s41371-020-00477-1. PMID: 33437020Free PMC Article
Gender Differences in Hypertension.
Song JJ, Ma Z, Wang J, Chen LX, Zhong JC
J Cardiovasc Transl Res 2020 Feb;13(1):47-54. Epub 2019 May 1 doi: 10.1007/s12265-019-09888-z. PMID: 31044374
Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.
Cohen JB, Lotito MJ, Trivedi UK, Denker MG, Cohen DL, Townsend RR
Ann Intern Med 2019 Jun 18;170(12):853-862. Epub 2019 Jun 11 doi: 10.7326/M19-0223. PMID: 31181575Free PMC Article

Clinical prediction guides

Relationship between clinic and ambulatory blood pressure and mortality: an observational cohort study in 59 124 patients.
Staplin N, de la Sierra A, Ruilope LM, Emberson JR, Vinyoles E, Gorostidi M, Ruiz-Hurtado G, Segura J, Baigent C, Williams B
Lancet 2023 Jun 17;401(10393):2041-2050. Epub 2023 May 5 doi: 10.1016/S0140-6736(23)00733-X. PMID: 37156250
Guidelines-similarities and dissimilarities: a systematic review of international clinical practice guidelines for pregnancy hypertension.
Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743
Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.
Cohen JB, Lotito MJ, Trivedi UK, Denker MG, Cohen DL, Townsend RR
Ann Intern Med 2019 Jun 18;170(12):853-862. Epub 2019 Jun 11 doi: 10.7326/M19-0223. PMID: 31181575Free PMC Article
Measurement of Blood Pressure in Humans: A Scientific Statement From the American Heart Association.
Muntner P, Shimbo D, Carey RM, Charleston JB, Gaillard T, Misra S, Myers MG, Ogedegbe G, Schwartz JE, Townsend RR, Urbina EM, Viera AJ, White WB, Wright JT Jr
Hypertension 2019 May;73(5):e35-e66. doi: 10.1161/HYP.0000000000000087. PMID: 30827125
Blood Pressure Self-Measurement.
Wagner S
Adv Exp Med Biol 2017;956:97-107. doi: 10.1007/5584_2016_151. PMID: 27757934

Recent systematic reviews

Guidelines-similarities and dissimilarities: a systematic review of international clinical practice guidelines for pregnancy hypertension.
Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743
Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.
Cohen JB, Lotito MJ, Trivedi UK, Denker MG, Cohen DL, Townsend RR
Ann Intern Med 2019 Jun 18;170(12):853-862. Epub 2019 Jun 11 doi: 10.7326/M19-0223. PMID: 31181575Free PMC Article
Is white-coat hypertension a risk factor for carotid atherosclerosis? A review and meta-analysis.
Cuspidi C, Sala C, Tadic M, Rescaldani M, Grassi G, Mancia G
Blood Press Monit 2015 Apr;20(2):57-63. doi: 10.1097/MBP.0000000000000094. PMID: 25405819
Systematic review and meta-analysis of the prevalence of resistant hypertension in treated hypertensive populations.
Achelrod D, Wenzel U, Frey S
Am J Hypertens 2015 Mar;28(3):355-61. Epub 2014 Aug 25 doi: 10.1093/ajh/hpu151. PMID: 25156625
Is epistaxis associated with arterial hypertension? A systematic review of the literature.
Kikidis D, Tsioufis K, Papanikolaou V, Zerva K, Hantzakos A
Eur Arch Otorhinolaryngol 2014 Feb;271(2):237-43. Epub 2013 Mar 29 doi: 10.1007/s00405-013-2450-z. PMID: 23539411

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