Gastric Intramucosal Adenocarcinoma

MedGen UID:: 459632
•Concept ID:: C2987406
•: Neoplastic Process

Synonyms:

Gastric Intramucosal Carcinoma; Gastric Intramucosal Invasive Neoplasia; Gastric Intramucosal Invasive Neoplasia/ Intramucosal Carcinoma

Definition

A neoplasm that arises from the gastric glandular epithelium and invades the lamina propria but not the submucosa. There is marked glandular crowding, branching and budding, intraluminal necrosis, and prominent mitotic activity. Desmoplastic changes may be present or absent. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVGastric Intramucosal Adenocarcinoma

Disease
- Neoplasm
  - Epithelial neoplasm
    - Carcinoma
      - Adenocarcinoma
        Intramucosal Adenocarcinoma
        Gastric Intramucosal Adenocarcinoma

Professional guidelines

PubMed

AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.

Sharma P, Shaheen NJ, Katzka D, Bergman JJGHM
Gastroenterology 2020 Feb;158(3):760-769. Epub 2019 Nov 12 doi: 10.1053/j.gastro.2019.09.051. PMID: 31730766

Emerging evidence supports grouping by location of early gastric carcinoma for appropriate clinical management in Chinese patients.

Huang Q, Li R, Xu GF, Zhou D, Fan XS, Zou XP
J Dig Dis 2018 Dec;19(12):730-736. Epub 2018 Nov 14 doi: 10.1111/1751-2980.12674. PMID: 30270559

Pathological features of total gastrectomy specimens from asymptomatic hereditary diffuse gastric cancer patients and implications for clinical management.

Rocha JP, Gullo I, Wen X, Devezas V, Baptista M, Oliveira C, Carneiro F
Histopathology 2018 Dec;73(6):878-886. Epub 2018 Oct 9 doi: 10.1111/his.13715. PMID: 30014492

See all (16)

Recent clinical studies

Diagnosis

Gastric intramucosal adenocarcinoma with an invasive micropapillary carcinoma component.

Tanaka H, Baba Y, Sase T, Isono Y, Matsusaki S, Saito T, Okano H, Mukai K, Murata T, Watanabe G
Clin J Gastroenterol 2015 Feb;8(1):14-7. Epub 2014 Nov 29 doi: 10.1007/s12328-014-0541-z. PMID: 25432661

Intramucosal stomach adenocarcinoma metastasizing as a large intraabdominal mass with focal choriocarcinomatous differentiation.

Fujiyoshi Y, Jiang S, Feng X
Int J Clin Exp Pathol 2012;5(8):845-51. Epub 2012 Oct 1 PMID: 23071868 Free PMC Article

Diffuse large B-cell lymphoma with concurrent gastric adenocarcinoma: case report and literature review.

Hu XR, Hu YX, Fu HR, Sheng LX, Huang WJ, Hu K, Huang H, Xie WZ
J Int Med Res 2011;39(5):2051-8. doi: 10.1177/147323001103900554. PMID: 22118012

See all (3)