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Acute esophagitis

MedGen UID:
472890
•Concept ID:
C0149882
•
Disease or Syndrome
Synonym: Acute Esophagitis
SNOMED CT: Acute esophagitis (409656006)

Definition

An acute inflammatory process affecting the esophageal wall. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute esophagitis

Professional guidelines

PubMed

Prevention and management of acute esophageal toxicity during concomitant chemoradiotherapy for locally advanced lung cancer.
Borghetti P, Imbrescia J, Volpi G, Costantino G, Cossali G, Greco D, Pastorello E, La Mattina S, Bonù ML, Tomasini D, Buglione M
Tumori 2022 Oct;108(5):470-476. Epub 2021 Jun 24 doi: 10.1177/03008916211025609. PMID: 34165018
Management of normal tissue toxicity associated with chemoradiation (primary skin, esophagus, and lung).
Yazbeck VY, Villaruz L, Haley M, Socinski MA
Cancer J 2013 May-Jun;19(3):231-7. doi: 10.1097/PPO.0b013e31829453fb. PMID: 23708070Free PMC Article
Treatment-related esophagitis.
Werner-Wasik M
Semin Oncol 2005 Apr;32(2 Suppl 3):S60-6. doi: 10.1053/j.seminoncol.2005.03.011. PMID: 16015537

Recent clinical studies

Etiology

Radiobiological modeling of acute esophagitis after radiation therapy of head, neck, and thorax tumors: The influence of chemo-radiation.
Alizade-Harakiyan M, Jangjoo AG, Jafari-Koshki T, Fatemi A, Mesbahi A
J Cancer Res Ther 2022 Oct-Dec;18(6):1706-1715. doi: 10.4103/jcrt.JCRT_271_20. PMID: 36412433
Early Prediction of Acute Esophagitis for Adaptive Radiation Therapy.
Alam SR, Zhang P, Zhang SY, Chen I, Rimner A, Tyagi N, Hu YC, Lu W, Yorke ED, Deasy JO, Thor M
Int J Radiat Oncol Biol Phys 2021 Jul 1;110(3):883-892. Epub 2021 Jan 13 doi: 10.1016/j.ijrobp.2021.01.007. PMID: 33453309Free PMC Article
Thoracic Radiation Normal Tissue Injury.
Simone CB 2nd
Semin Radiat Oncol 2017 Oct;27(4):370-377. doi: 10.1016/j.semradonc.2017.04.009. PMID: 28865520
Esophagitis, treatment-related toxicity in non-small cell lung cancer.
Bar-Ad V, Ohri N, Werner-Wasik M
Rev Recent Clin Trials 2012 Feb;7(1):31-5. doi: 10.2174/157488712799363235. PMID: 21864251Free PMC Article
Treatment-related esophagitis.
Werner-Wasik M
Semin Oncol 2005 Apr;32(2 Suppl 3):S60-6. doi: 10.1053/j.seminoncol.2005.03.011. PMID: 16015537

Diagnosis

Civatte Bodies in Pediatric Esophageal Biopsies: Does Lichen Esophagitis Pattern Occur in Children?
Saab-Chalhoub MW, Correa H, Anderson JL, Kovach AE, Salaria SN
Pediatr Dev Pathol 2022 Jul-Aug;25(4):458-465. Epub 2022 Apr 22 doi: 10.1177/10935266221090081. PMID: 35452319
The esophageal dose-volume parameters for predicting Grade I-II acute esophagitis correlated with weight loss and serum albumin decrease in lung cancer radiotherapy.
Kaymak Cerkesli ZA, Ozkan EE, Ozseven A
J Cancer Res Ther 2021 Jan-Mar;17(1):94-98. doi: 10.4103/jcrt.JCRT_410_19. PMID: 33723138
Early Prediction of Acute Esophagitis for Adaptive Radiation Therapy.
Alam SR, Zhang P, Zhang SY, Chen I, Rimner A, Tyagi N, Hu YC, Lu W, Yorke ED, Deasy JO, Thor M
Int J Radiat Oncol Biol Phys 2021 Jul 1;110(3):883-892. Epub 2021 Jan 13 doi: 10.1016/j.ijrobp.2021.01.007. PMID: 33453309Free PMC Article
Recommendation for supportive care in patients receiving concurrent chemotherapy and radiotherapy for lung cancer.
De Ruysscher D, Faivre-Finn C, Nackaerts K, Jordan K, Arends J, Douillard JY, Ricardi U, Peters S
Ann Oncol 2020 Jan;31(1):41-49. doi: 10.1016/j.annonc.2019.10.003. PMID: 31912794
What is the best way to manage GERD symptoms in the elderly?
Bacak BS, Patel M, Tweed E, Danis P
J Fam Pract 2006 Mar;55(3):251-4, 258. PMID: 16510061

Therapy

Evaluating the relationship between dosimetric parameters and esophagitis in patients who experienced radiotherapy in the cervicothoracic region.
Siavashpour Z, Rabiee N, Bakhshandeh M, Anvari A, Zayeri F
J Cancer Res Ther 2022 Jul-Sep;18(4):1009-1015. doi: 10.4103/jcrt.JCRT_91_20. PMID: 36149154
Prevention and management of acute esophageal toxicity during concomitant chemoradiotherapy for locally advanced lung cancer.
Borghetti P, Imbrescia J, Volpi G, Costantino G, Cossali G, Greco D, Pastorello E, La Mattina S, Bonù ML, Tomasini D, Buglione M
Tumori 2022 Oct;108(5):470-476. Epub 2021 Jun 24 doi: 10.1177/03008916211025609. PMID: 34165018
Early Prediction of Acute Esophagitis for Adaptive Radiation Therapy.
Alam SR, Zhang P, Zhang SY, Chen I, Rimner A, Tyagi N, Hu YC, Lu W, Yorke ED, Deasy JO, Thor M
Int J Radiat Oncol Biol Phys 2021 Jul 1;110(3):883-892. Epub 2021 Jan 13 doi: 10.1016/j.ijrobp.2021.01.007. PMID: 33453309Free PMC Article
Treatment-related esophagitis.
Werner-Wasik M
Semin Oncol 2005 Apr;32(2 Suppl 3):S60-6. doi: 10.1053/j.seminoncol.2005.03.011. PMID: 16015537
Therapy and prophylaxis of acute and late radiation-induced sequelae of the esophagus.
Zimmermann FB, Geinitz H, Feldmann HJ
Strahlenther Onkol 1998 Nov;174 Suppl 3:78-81. PMID: 9830464

Prognosis

Radiobiological modeling of acute esophagitis after radiation therapy of head, neck, and thorax tumors: The influence of chemo-radiation.
Alizade-Harakiyan M, Jangjoo AG, Jafari-Koshki T, Fatemi A, Mesbahi A
J Cancer Res Ther 2022 Oct-Dec;18(6):1706-1715. doi: 10.4103/jcrt.JCRT_271_20. PMID: 36412433
Evaluating the relationship between dosimetric parameters and esophagitis in patients who experienced radiotherapy in the cervicothoracic region.
Siavashpour Z, Rabiee N, Bakhshandeh M, Anvari A, Zayeri F
J Cancer Res Ther 2022 Jul-Sep;18(4):1009-1015. doi: 10.4103/jcrt.JCRT_91_20. PMID: 36149154
Prevention and management of acute esophageal toxicity during concomitant chemoradiotherapy for locally advanced lung cancer.
Borghetti P, Imbrescia J, Volpi G, Costantino G, Cossali G, Greco D, Pastorello E, La Mattina S, Bonù ML, Tomasini D, Buglione M
Tumori 2022 Oct;108(5):470-476. Epub 2021 Jun 24 doi: 10.1177/03008916211025609. PMID: 34165018
Early Prediction of Acute Esophagitis for Adaptive Radiation Therapy.
Alam SR, Zhang P, Zhang SY, Chen I, Rimner A, Tyagi N, Hu YC, Lu W, Yorke ED, Deasy JO, Thor M
Int J Radiat Oncol Biol Phys 2021 Jul 1;110(3):883-892. Epub 2021 Jan 13 doi: 10.1016/j.ijrobp.2021.01.007. PMID: 33453309Free PMC Article
Esophagitis, treatment-related toxicity in non-small cell lung cancer.
Bar-Ad V, Ohri N, Werner-Wasik M
Rev Recent Clin Trials 2012 Feb;7(1):31-5. doi: 10.2174/157488712799363235. PMID: 21864251Free PMC Article

Clinical prediction guides

Radiobiological modeling of acute esophagitis after radiation therapy of head, neck, and thorax tumors: The influence of chemo-radiation.
Alizade-Harakiyan M, Jangjoo AG, Jafari-Koshki T, Fatemi A, Mesbahi A
J Cancer Res Ther 2022 Oct-Dec;18(6):1706-1715. doi: 10.4103/jcrt.JCRT_271_20. PMID: 36412433
Acute and Late Esophageal Toxicity After SABR to Thoracic Tumors Near or Abutting the Esophagus.
Sodji QH, Ko R, von Eyben R, Owen SG, Capaldi DPI, Bush K, Binkley MS, Alrowais F, Pickthorn B, Maxim PG, Gensheimer MF, Diehn M, Loo BW Jr
Int J Radiat Oncol Biol Phys 2022 Apr 1;112(5):1144-1153. Epub 2021 Dec 20 doi: 10.1016/j.ijrobp.2021.12.008. PMID: 34942312
Prevention and management of acute esophageal toxicity during concomitant chemoradiotherapy for locally advanced lung cancer.
Borghetti P, Imbrescia J, Volpi G, Costantino G, Cossali G, Greco D, Pastorello E, La Mattina S, Bonù ML, Tomasini D, Buglione M
Tumori 2022 Oct;108(5):470-476. Epub 2021 Jun 24 doi: 10.1177/03008916211025609. PMID: 34165018
Early Prediction of Acute Esophagitis for Adaptive Radiation Therapy.
Alam SR, Zhang P, Zhang SY, Chen I, Rimner A, Tyagi N, Hu YC, Lu W, Yorke ED, Deasy JO, Thor M
Int J Radiat Oncol Biol Phys 2021 Jul 1;110(3):883-892. Epub 2021 Jan 13 doi: 10.1016/j.ijrobp.2021.01.007. PMID: 33453309Free PMC Article
Esophagitis, treatment-related toxicity in non-small cell lung cancer.
Bar-Ad V, Ohri N, Werner-Wasik M
Rev Recent Clin Trials 2012 Feb;7(1):31-5. doi: 10.2174/157488712799363235. PMID: 21864251Free PMC Article

Recent systematic reviews

Radiation dose escalation with modified fractionation schedules for locally advanced NSCLC: A systematic review.
Zehentmayr F, Grambozov B, Kaiser J, Fastner G, Sedlmayer F
Thorac Cancer 2020 Jun;11(6):1375-1385. Epub 2020 Apr 22 doi: 10.1111/1759-7714.13451. PMID: 32323484Free PMC Article
Toxicity of concurrent radiochemotherapy for locally advanced non--small-cell lung cancer: a systematic review of the literature.
Koning CC, Wouterse SJ, Daams JG, Uitterhoeve LL, van den Heuvel MM, Belderbos JS
Clin Lung Cancer 2013 Sep;14(5):481-7. Epub 2013 Jun 7 doi: 10.1016/j.cllc.2013.03.002. PMID: 23751283
Comparison of the efficacy and acute toxicity of weekly versus daily chemoradiotherapy for non-small-cell lung cancer: a meta-analysis.
Rakovitch E, Tsao M, Ung Y, Pignol JP, Cheung P, Chow E
Int J Radiat Oncol Biol Phys 2004 Jan 1;58(1):196-203. doi: 10.1016/s0360-3016(03)01447-0. PMID: 14697439

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