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Brachial Plexus Palsy

MedGen UID:
473191
•Concept ID:
C0541435
•
Disease or Syndrome

Definition

An injury that results in paralysis of the muscles of the shoulder, arm, and hand. It manifests as lack of mobility in the arm. In the majority of cases there is spontaneous recovery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBrachial Plexus Palsy

Professional guidelines

PubMed

Neonatal brachial plexus palsy - early diagnosis and treatment.
Berényi M, Szeredai M, Cseh Á
Ideggyogy Sz 2022 Jul 30;75(7-08):247-252. doi: 10.18071/isz.75.0247. PMID: 35916611
Neonatal brachial plexus palsy--management and prognostic factors.
Yang LJ
Semin Perinatol 2014 Jun;38(4):222-34. doi: 10.1053/j.semperi.2014.04.009. PMID: 24863029
Shoulder dystocia: management and documentation.
Stitely ML, Gherman RB
Semin Perinatol 2014 Jun;38(4):194-200. doi: 10.1053/j.semperi.2014.04.004. PMID: 24863024

Recent clinical studies

Etiology

Brachial Plexus Birth Injuries.
Lin JS, Samora JB
Orthop Clin North Am 2022 Apr;53(2):167-177. Epub 2022 Mar 5 doi: 10.1016/j.ocl.2021.11.003. PMID: 35365261
Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review.
Sicari M, Longhi M, D'Angelo G, Boetto V, Lavorato A, Cocchini L, Beatrici M, Battiston B, Garbossa D, Massazza G, Titolo P
Eur J Phys Rehabil Med 2022 Feb;58(1):43-50. Epub 2021 Nov 8 doi: 10.23736/S1973-9087.21.06886-6. PMID: 34747579Free PMC Article
Evaluation and Management of Fetal Macrosomia.
Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Constraint-induced movement therapy for children with neonatal brachial plexus palsy: a randomized crossover trial.
Werner JM, Berggren J, Loiselle J, Lee GK
Dev Med Child Neurol 2021 May;63(5):545-551. Epub 2020 Nov 21 doi: 10.1111/dmcn.14741. PMID: 33219706
Obstetrical Brachial Plexus Palsy.
O'Berry P, Brown M, Phillips L, Evans SH
Curr Probl Pediatr Adolesc Health Care 2017 Jul;47(7):151-155. Epub 2017 Jul 12 doi: 10.1016/j.cppeds.2017.06.003. PMID: 28709767

Diagnosis

Neonatal brachial plexus palsy - early diagnosis and treatment.
Berényi M, Szeredai M, Cseh Á
Ideggyogy Sz 2022 Jul 30;75(7-08):247-252. doi: 10.18071/isz.75.0247. PMID: 35916611
Evaluation and Management of Fetal Macrosomia.
Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Obstetrical Brachial Plexus Palsy.
O'Berry P, Brown M, Phillips L, Evans SH
Curr Probl Pediatr Adolesc Health Care 2017 Jul;47(7):151-155. Epub 2017 Jul 12 doi: 10.1016/j.cppeds.2017.06.003. PMID: 28709767
Neonatal brachial plexus palsy--management and prognostic factors.
Yang LJ
Semin Perinatol 2014 Jun;38(4):222-34. doi: 10.1053/j.semperi.2014.04.009. PMID: 24863029
Evaluation and management of brachial plexus birth palsy.
Abzug JM, Kozin SH
Orthop Clin North Am 2014 Apr;45(2):225-32. Epub 2014 Jan 29 doi: 10.1016/j.ocl.2013.12.004. PMID: 24684916

Therapy

Risk factors for neonatal brachial plexus palsy attributed to anatomy, physiology, and evolution.
Dunbar DC, Vilensky JA, Suárez-Quian CA, Shen PY, Metaizeau JP, Supakul N
Clin Anat 2021 Sep;34(6):884-898. Epub 2021 Jun 1 doi: 10.1002/ca.23739. PMID: 33904192
Constraint-induced movement therapy for children with neonatal brachial plexus palsy: a randomized crossover trial.
Werner JM, Berggren J, Loiselle J, Lee GK
Dev Med Child Neurol 2021 May;63(5):545-551. Epub 2020 Nov 21 doi: 10.1111/dmcn.14741. PMID: 33219706
Obstetrical Brachial Plexus Palsy.
O'Berry P, Brown M, Phillips L, Evans SH
Curr Probl Pediatr Adolesc Health Care 2017 Jul;47(7):151-155. Epub 2017 Jul 12 doi: 10.1016/j.cppeds.2017.06.003. PMID: 28709767
Update in electromyography.
Pitt M
Curr Opin Pediatr 2013 Dec;25(6):676-81. doi: 10.1097/MOP.0000000000000023. PMID: 24136299
Obstetric brachial plexus palsy: treatment strategy, long-term results, and prognosis.
Bahm J, Ocampo-Pavez C, Disselhorst-Klug C, Sellhaus B, Weis J
Dtsch Arztebl Int 2009 Feb;106(6):83-90. Epub 2009 Feb 6 doi: 10.3238/arztebl.2009.0083. PMID: 19562016Free PMC Article

Prognosis

Obstetrical Brachial Plexus Palsy.
O'Berry P, Brown M, Phillips L, Evans SH
Curr Probl Pediatr Adolesc Health Care 2017 Jul;47(7):151-155. Epub 2017 Jul 12 doi: 10.1016/j.cppeds.2017.06.003. PMID: 28709767
Neonatal brachial plexus palsy: a permanent challenge.
Heise CO, Martins R, Siqueira M
Arq Neuropsiquiatr 2015 Sep;73(9):803-8. doi: 10.1590/0004-282X20150105. PMID: 26352501
Neonatal brachial plexus palsy--management and prognostic factors.
Yang LJ
Semin Perinatol 2014 Jun;38(4):222-34. doi: 10.1053/j.semperi.2014.04.009. PMID: 24863029
Neonatal brachial plexus palsy: incidence, prevalence, and temporal trends.
Chauhan SP, Blackwell SB, Ananth CV
Semin Perinatol 2014 Jun;38(4):210-8. doi: 10.1053/j.semperi.2014.04.007. PMID: 24863027
Update in electromyography.
Pitt M
Curr Opin Pediatr 2013 Dec;25(6):676-81. doi: 10.1097/MOP.0000000000000023. PMID: 24136299

Clinical prediction guides

Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review.
Sicari M, Longhi M, D'Angelo G, Boetto V, Lavorato A, Cocchini L, Beatrici M, Battiston B, Garbossa D, Massazza G, Titolo P
Eur J Phys Rehabil Med 2022 Feb;58(1):43-50. Epub 2021 Nov 8 doi: 10.23736/S1973-9087.21.06886-6. PMID: 34747579Free PMC Article
Constraint-induced movement therapy for children with neonatal brachial plexus palsy: a randomized crossover trial.
Werner JM, Berggren J, Loiselle J, Lee GK
Dev Med Child Neurol 2021 May;63(5):545-551. Epub 2020 Nov 21 doi: 10.1111/dmcn.14741. PMID: 33219706
Neonatal brachial plexus palsy--management and prognostic factors.
Yang LJ
Semin Perinatol 2014 Jun;38(4):222-34. doi: 10.1053/j.semperi.2014.04.009. PMID: 24863029
Update in electromyography.
Pitt M
Curr Opin Pediatr 2013 Dec;25(6):676-81. doi: 10.1097/MOP.0000000000000023. PMID: 24136299
Obstetrical brachial plexus palsy.
Borschel GH, Clarke HM
Plast Reconstr Surg 2009 Jul;124(1 Suppl):144e-155e. doi: 10.1097/PRS.0b013e3181a80798. PMID: 19568147

Recent systematic reviews

A systematic review of brachial plexus injuries after caesarean birth: challenging delivery?
Jaufuraully S, Lakshmi Narasimhan A, Stott D, Attilakos G, Siassakos D
BMC Pregnancy Childbirth 2023 May 17;23(1):361. doi: 10.1186/s12884-023-05696-1. PMID: 37198580Free PMC Article
Radiographic imaging modalities for perinatal brachial plexus palsy: a systematic review.
Girard AO, Suresh V, Lopez CD, Seal SM, Tuffaha SH, Redett RJ, Halsey JN
Childs Nerv Syst 2022 Jul;38(7):1241-1258. Epub 2022 May 10 doi: 10.1007/s00381-022-05538-z. PMID: 35536348
Surgical timing in neonatal brachial plexus palsy: A PRISMA-IPD systematic review.
Srinivasan N, Mahajan J, Gupta S, Shah YM, Shafei J, Levidy MF, Abdelmalek G, Pant K, Jain K, Zhao C, Chu A, McGrath A
Microsurgery 2022 May;42(4):381-390. Epub 2022 Feb 11 doi: 10.1002/micr.30871. PMID: 35147253Free PMC Article
Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review.
Sicari M, Longhi M, D'Angelo G, Boetto V, Lavorato A, Cocchini L, Beatrici M, Battiston B, Garbossa D, Massazza G, Titolo P
Eur J Phys Rehabil Med 2022 Feb;58(1):43-50. Epub 2021 Nov 8 doi: 10.23736/S1973-9087.21.06886-6. PMID: 34747579Free PMC Article
Risk factors for neonatal brachial plexus palsy: a systematic review and meta-analysis.
Van der Looven R, Le Roy L, Tanghe E, Samijn B, Roets E, Pauwels N, Deschepper E, De Muynck M, Vingerhoets G, Van den Broeck C
Dev Med Child Neurol 2020 Jun;62(6):673-683. Epub 2019 Oct 31 doi: 10.1111/dmcn.14381. PMID: 31670385

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