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Myringosclerosis

MedGen UID:
488426
•Concept ID:
C3494473
•
Disease or Syndrome
Synonym: Myringoscleroses

Definition

The formation of dense connective tissue and calcification in the TYMPANIC MEMBRANE that does not necessarily cause or lead to loss of hearing. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyringosclerosis

Professional guidelines

PubMed

The effect of Vitamin E treatment on the development of myringosclerosis after ventilation tube insertion.
Uneri C, Bağlam T, Yazici M
Int J Pediatr Otorhinolaryngol 2006 Jun;70(6):1045-8. Epub 2005 Dec 20 doi: 10.1016/j.ijporl.2005.10.019. PMID: 16368152
Late results of treatment with ventilation tubes for secretory otitis media in ENT practice.
Sederberg-Olsen JF, Sederberg-Olsen AE, Jensen AM
Acta Otolaryngol 1989 Nov-Dec;108(5-6):448-55. doi: 10.3109/00016488909125552. PMID: 2589073

Recent clinical studies

Etiology

Myringosclerosis as a predictor of the requirement for a permanent pacemaker in patients with drug-related atrioventricular block.
Cosgun MS, Hamur H, Degirmenci H, Coskun R, Karayumak MR, Karabiyik U, Salcan I
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2022 Dec;166(4):412-417. Epub 2022 Jun 21 doi: 10.5507/bp.2022.030. PMID: 35734916
Hearing outcome after tympanoplasty type III.
Tihanyi A, Speck I, Wolff K, Arnold P, Aschendorff A, Arndt S
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4353-4362. Epub 2022 Jan 24 doi: 10.1007/s00405-021-07190-w. PMID: 35072768Free PMC Article
Myringosclerosis in hemodialysis patients with hyperparathyroidism.
Alnahal A, Waheed M, Abdelhamid WAR
Saudi J Kidney Dis Transpl 2020 Nov-Dec;31(6):1303-1309. doi: 10.4103/1319-2442.308339. PMID: 33565442
Analysis of Risk Factors for Myringosclerosis Formation after Ventilation Tube Insertion.
Kim EH, Park KW, Lee SH, Kim BJ, Park YH
J Korean Med Sci 2020 Apr 6;35(13):e83. doi: 10.3346/jkms.2020.35.e83. PMID: 32242343Free PMC Article
Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?
Branco C, Paço J
Acta Otorrinolaringol Esp (Engl Ed) 2017 Nov-Dec;68(6):323-327. Epub 2017 May 15 doi: 10.1016/j.otorri.2017.02.003. PMID: 28522133

Diagnosis

Does myringosclerosis affect the success of butterfly myringoplasty?
Akyigit A, Karlidag T, Eroglu O, Akın FU, Kaygusuz I
Auris Nasus Larynx 2023 Dec;50(6):854-858. Epub 2023 Apr 5 doi: 10.1016/j.anl.2023.03.005. PMID: 37029065
Computer-aided diagnosis of external and middle ear conditions: A machine learning approach.
Viscaino M, Maass JC, Delano PH, Torrente M, Stott C, Auat Cheein F
PLoS One 2020;15(3):e0229226. Epub 2020 Mar 12 doi: 10.1371/journal.pone.0229226. PMID: 32163427Free PMC Article
Cilia and Ear.
Piatti G, De Santi MM, Torretta S, Pignataro L, Soi D, Ambrosetti U
Ann Otol Rhinol Laryngol 2017 Apr;126(4):322-327. Epub 2017 Feb 12 doi: 10.1177/0003489417691299. PMID: 28290230
The windows of the inner ear.
Thomson S, Madani G
Clin Radiol 2014 Mar;69(3):e146-52. Epub 2013 Dec 22 doi: 10.1016/j.crad.2013.10.020. PMID: 24365668
Hearing loss.
Weissman JL
Radiology 1996 Jun;199(3):593-611. doi: 10.1148/radiology.199.3.8637972. PMID: 8637972

Therapy

Myringosclerosis as a predictor of the requirement for a permanent pacemaker in patients with drug-related atrioventricular block.
Cosgun MS, Hamur H, Degirmenci H, Coskun R, Karayumak MR, Karabiyik U, Salcan I
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2022 Dec;166(4):412-417. Epub 2022 Jun 21 doi: 10.5507/bp.2022.030. PMID: 35734916
Analysis of Risk Factors for Myringosclerosis Formation after Ventilation Tube Insertion.
Kim EH, Park KW, Lee SH, Kim BJ, Park YH
J Korean Med Sci 2020 Apr 6;35(13):e83. doi: 10.3346/jkms.2020.35.e83. PMID: 32242343Free PMC Article
Stapes Release in Tympanosclerosis.
Bedri EH, Teferi N, Redleaf M
Otol Neurotol 2018 Feb;39(2):184-188. doi: 10.1097/MAO.0000000000001639. PMID: 29210944
Predictive factors for the appearance of myringosclerosis after myringotomy with ventilation tube placement: randomized study.
Branco C, Monteiro D, Paço J
Eur Arch Otorhinolaryngol 2017 Jan;274(1):79-84. Epub 2016 Jul 9 doi: 10.1007/s00405-016-4194-z. PMID: 27395069
Myringosclerosis after tympanostomy tube insertion: relation with tube retention time and gender.
Yaman H, Guclu E, Yilmaz S, Ozturk O
Auris Nasus Larynx 2010 Dec;37(6):676-9. Epub 2010 Apr 14 doi: 10.1016/j.anl.2010.02.007. PMID: 20392579

Prognosis

Myringosclerosis as a predictor of the requirement for a permanent pacemaker in patients with drug-related atrioventricular block.
Cosgun MS, Hamur H, Degirmenci H, Coskun R, Karayumak MR, Karabiyik U, Salcan I
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2022 Dec;166(4):412-417. Epub 2022 Jun 21 doi: 10.5507/bp.2022.030. PMID: 35734916
Hearing outcome after tympanoplasty type III.
Tihanyi A, Speck I, Wolff K, Arnold P, Aschendorff A, Arndt S
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4353-4362. Epub 2022 Jan 24 doi: 10.1007/s00405-021-07190-w. PMID: 35072768Free PMC Article
Analysis of Risk Factors for Myringosclerosis Formation after Ventilation Tube Insertion.
Kim EH, Park KW, Lee SH, Kim BJ, Park YH
J Korean Med Sci 2020 Apr 6;35(13):e83. doi: 10.3346/jkms.2020.35.e83. PMID: 32242343Free PMC Article
Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?
Branco C, Paço J
Acta Otorrinolaringol Esp (Engl Ed) 2017 Nov-Dec;68(6):323-327. Epub 2017 May 15 doi: 10.1016/j.otorri.2017.02.003. PMID: 28522133
Myringosclerosis after tympanostomy tube insertion: relation with tube retention time and gender.
Yaman H, Guclu E, Yilmaz S, Ozturk O
Auris Nasus Larynx 2010 Dec;37(6):676-9. Epub 2010 Apr 14 doi: 10.1016/j.anl.2010.02.007. PMID: 20392579

Clinical prediction guides

Myringosclerosis as a predictor of the requirement for a permanent pacemaker in patients with drug-related atrioventricular block.
Cosgun MS, Hamur H, Degirmenci H, Coskun R, Karayumak MR, Karabiyik U, Salcan I
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2022 Dec;166(4):412-417. Epub 2022 Jun 21 doi: 10.5507/bp.2022.030. PMID: 35734916
Hearing outcome after tympanoplasty type III.
Tihanyi A, Speck I, Wolff K, Arnold P, Aschendorff A, Arndt S
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4353-4362. Epub 2022 Jan 24 doi: 10.1007/s00405-021-07190-w. PMID: 35072768Free PMC Article
Development and Validation of a Clinical Score for Predicting the Risk of Tympanosclerosis Before Surgery.
Dong Z, Zhou M, Ye G, Ye J, Xiao M
Ear Nose Throat J 2022 May;101(4):NP169-NP177. Epub 2020 Sep 7 doi: 10.1177/0145561320951676. PMID: 32894702
Predictive factors for the appearance of myringosclerosis after myringotomy with ventilation tube placement: randomized study.
Branco C, Monteiro D, Paço J
Eur Arch Otorhinolaryngol 2017 Jan;274(1):79-84. Epub 2016 Jul 9 doi: 10.1007/s00405-016-4194-z. PMID: 27395069
Myringosclerosis after tympanostomy tube insertion: relation with tube retention time and gender.
Yaman H, Guclu E, Yilmaz S, Ozturk O
Auris Nasus Larynx 2010 Dec;37(6):676-9. Epub 2010 Apr 14 doi: 10.1016/j.anl.2010.02.007. PMID: 20392579

Recent systematic reviews

Otitis media with effusion in children.
Williamson I
BMJ Clin Evid 2011 Jan 12;2011 PMID: 21477396Free PMC Article
Otitis media with effusion in children.
Williamson I
BMJ Clin Evid 2007 Aug 1;2007 PMID: 19454116Free PMC Article

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