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Paralytic lagophthalmos

MedGen UID:
509844
•Concept ID:
C0155197
•
Disease or Syndrome
Synonyms: Lagophthalmos, Paralytic; Paralytic Lagophthalmos
SNOMED CT: Paralytic lagophthalmos (59890007)
 
HPO: HP:0030003
Monarch Initiative: MONDO:0001603

Definition

A type of lagophthalmos that occurs in association with facial nerve palsy. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParalytic lagophthalmos

Professional guidelines

PubMed

Hyaluronic acid gel weight: a nonsurgical option for the management of paralytic lagophthalmos.
Martín-Oviedo C, García I, Lowy A, Scola E, Aristegui M, Scola B
Laryngoscope 2013 Dec;123(12):E91-6. Epub 2013 Oct 1 doi: 10.1002/lary.23936. PMID: 24122715
Upper eyelid postseptal weight placement for treatment of paralytic lagophthalmos.
Rozen S, Lehrman C
Plast Reconstr Surg 2013 Jun;131(6):1253-1265. doi: 10.1097/PRS.0b013e31828be961. PMID: 23714789
Lid loading for treatment of paralytic lagophthalmos.
Yu Y, Sun J, Chen L, Liu L
Aesthetic Plast Surg 2011 Dec;35(6):1165-71. Epub 2011 May 10 doi: 10.1007/s00266-011-9740-x. PMID: 21556983

Recent clinical studies

Etiology

Lipofilling of the upper eyelid to treat paralytic lagophthalmos.
Biglioli F, Rabbiosi D, Bolognesi F, Cucurullo M, Dessy M, Ciardiello C, Battista VMA, Tarabbia F, Dell'Aversana Orabona G, Marchetti C, Allevi F
Br J Oral Maxillofac Surg 2020 Jun;58(5):558-563. Epub 2020 Mar 4 doi: 10.1016/j.bjoms.2020.02.017. PMID: 32145955
Septal chondromucosal grafts in paralytic lagophthalmos.
Alban R, Anne Sophie F, Thibault V, Clément D, Sophie B, Pascal R
J Plast Reconstr Aesthet Surg 2018 Sep;71(9):1352-1361. Epub 2018 Jun 5 doi: 10.1016/j.bjps.2018.04.021. PMID: 30007536
Recession and Extirpation of the Lower Eyelid Retractors for Paralytic Lagophthalmos.
Compton CJ, Clark JD, Nunery WR, Lee HB
Ophthalmic Plast Reconstr Surg 2015 Jul-Aug;31(4):323-4. doi: 10.1097/IOP.0000000000000485. PMID: 26020720
Treatment of the periocular complex in paralytic lagophthalmos.
Loyo M, Jones D, Lee LN, Collar RM, Molendijk J, Boahene KD, Ishii LE, Byrne PJ
Ann Otol Rhinol Laryngol 2015 Apr;124(4):273-9. Epub 2014 Dec 4 doi: 10.1177/0003489414560584. PMID: 25480756
Alternative surgical treatment of paralytic lagophthalmos using autogenic cartilage grafts and canthopexy.
Friedhofer H, Coltro PS, Vassiliadis AH, Nigro MV, Saito FL, Moura T, Faria JC, Ferreira MC
Ann Plast Surg 2013 Aug;71(2):135-9. doi: 10.1097/SAP.0b013e318248b87c. PMID: 23728241

Diagnosis

Symptomatic and Histological Tissue Reaction to Upper Eyelid Platinum Weight.
Ghodke A, Miller KM, Miller MQ
Ann Otol Rhinol Laryngol 2023 Oct;132(10):1271-1274. Epub 2023 Jan 10 doi: 10.1177/00034894221148016. PMID: 36625205
Corneal Neurotization in the Setting of Facial Paralysis: A Comprehensive Review of Surgical Techniques.
Ziai K, Thomas S, Weller C, Lighthall JG
J Craniofac Surg 2021 Sep 1;32(6):2210-2214. doi: 10.1097/SCS.0000000000007590. PMID: 33654040
Evaluation of Patients with Facial Palsy and Ophthalmic Sequelae: A 23-Year Retrospective Review.
Joseph SS, Joseph AW, Smith JI, Niziol LM, Musch DC, Nelson CC
Ophthalmic Epidemiol 2017 Oct;24(5):341-345. Epub 2017 Mar 20 doi: 10.1080/09286586.2017.1294186. PMID: 28319442
Post-septal upper eyelid loading for treatment of exposure keratopathy secondary to non-cicatricial lagophthalmos.
Wagh VK, Lim WS, Cascone NC, Morley AM
Orbit 2016 Oct;35(5):239-44. Epub 2016 Aug 10 doi: 10.1080/01676830.2016.1176213. PMID: 27541938
Lagophthalmos.
Pereira MV, Glória AL
Semin Ophthalmol 2010 May;25(3):72-8. doi: 10.3109/08820538.2010.488578. PMID: 20590416

Therapy

The effect of various muscle transfer procedures on eye closure and blinking in longstanding facial palsy patients.
Dhooghe N, Brusselle M, Ureel M, Sinove Y, Vermeersch H, Blondeel P
J Plast Reconstr Aesthet Surg 2024 Feb;89:57-71. Epub 2023 Nov 24 doi: 10.1016/j.bjps.2023.11.029. PMID: 38142623
Sutureless transconjunctival insertion of eyelid gold weight.
Ozturan O, Yenigun A, Senturk E, Aksoy F
Am J Otolaryngol 2023 Jul-Aug;44(4):103874. Epub 2023 Mar 30 doi: 10.1016/j.amjoto.2023.103874. PMID: 37011541
Spontaneous Blinking Kinetics on Paralytic Lagophthalmos After Lid Load with Gold Weight or Autogenous Temporalis Fascia Sling.
Wambier SP, Garcia DM, Cruz AA, Messias A
Curr Eye Res 2016 Apr;41(4):433-40. Epub 2015 May 27 doi: 10.3109/02713683.2015.1031252. PMID: 26016510
Lid loading for treatment of paralytic lagophthalmos.
Yu Y, Sun J, Chen L, Liu L
Aesthetic Plast Surg 2011 Dec;35(6):1165-71. Epub 2011 May 10 doi: 10.1007/s00266-011-9740-x. PMID: 21556983
Treatment of paralytic lagophthalmos with gold weight implants covered by levator aponeurosis.
Lessa S, Nanci M, Sebastiá R, Flores E
Ophthalmic Plast Reconstr Surg 2009 May-Jun;25(3):189-93. doi: 10.1097/IOP.0b013e3181a13d72. PMID: 19454928

Prognosis

Septal chondromucosal grafts in paralytic lagophthalmos.
Alban R, Anne Sophie F, Thibault V, Clément D, Sophie B, Pascal R
J Plast Reconstr Aesthet Surg 2018 Sep;71(9):1352-1361. Epub 2018 Jun 5 doi: 10.1016/j.bjps.2018.04.021. PMID: 30007536
Recession and Extirpation of the Lower Eyelid Retractors for Paralytic Lagophthalmos.
Compton CJ, Clark JD, Nunery WR, Lee HB
Ophthalmic Plast Reconstr Surg 2015 Jul-Aug;31(4):323-4. doi: 10.1097/IOP.0000000000000485. PMID: 26020720
Treatment of the periocular complex in paralytic lagophthalmos.
Loyo M, Jones D, Lee LN, Collar RM, Molendijk J, Boahene KD, Ishii LE, Byrne PJ
Ann Otol Rhinol Laryngol 2015 Apr;124(4):273-9. Epub 2014 Dec 4 doi: 10.1177/0003489414560584. PMID: 25480756
Alternative surgical treatment of paralytic lagophthalmos using autogenic cartilage grafts and canthopexy.
Friedhofer H, Coltro PS, Vassiliadis AH, Nigro MV, Saito FL, Moura T, Faria JC, Ferreira MC
Ann Plast Surg 2013 Aug;71(2):135-9. doi: 10.1097/SAP.0b013e318248b87c. PMID: 23728241
Lid loading for treatment of paralytic lagophthalmos.
Yu Y, Sun J, Chen L, Liu L
Aesthetic Plast Surg 2011 Dec;35(6):1165-71. Epub 2011 May 10 doi: 10.1007/s00266-011-9740-x. PMID: 21556983

Clinical prediction guides

The effect of various muscle transfer procedures on eye closure and blinking in longstanding facial palsy patients.
Dhooghe N, Brusselle M, Ureel M, Sinove Y, Vermeersch H, Blondeel P
J Plast Reconstr Aesthet Surg 2024 Feb;89:57-71. Epub 2023 Nov 24 doi: 10.1016/j.bjps.2023.11.029. PMID: 38142623
Septal chondromucosal grafts in paralytic lagophthalmos.
Alban R, Anne Sophie F, Thibault V, Clément D, Sophie B, Pascal R
J Plast Reconstr Aesthet Surg 2018 Sep;71(9):1352-1361. Epub 2018 Jun 5 doi: 10.1016/j.bjps.2018.04.021. PMID: 30007536
Spontaneous Blinking Kinetics on Paralytic Lagophthalmos After Lid Load with Gold Weight or Autogenous Temporalis Fascia Sling.
Wambier SP, Garcia DM, Cruz AA, Messias A
Curr Eye Res 2016 Apr;41(4):433-40. Epub 2015 May 27 doi: 10.3109/02713683.2015.1031252. PMID: 26016510
Hyaluronic acid gel weight: a nonsurgical option for the management of paralytic lagophthalmos.
Martín-Oviedo C, García I, Lowy A, Scola E, Aristegui M, Scola B
Laryngoscope 2013 Dec;123(12):E91-6. Epub 2013 Oct 1 doi: 10.1002/lary.23936. PMID: 24122715
Blink lagophthalmos and dry eye keratopathy in patients with non-facial palsy: clinical features and management with upper eyelid loading.
Patel V, Daya SM, Lake D, Malhotra R
Ophthalmology 2011 Jan;118(1):197-202. Epub 2010 Nov 20 doi: 10.1016/j.ophtha.2010.04.037. PMID: 21093924

Recent systematic reviews

The effect of various muscle transfer procedures on eye closure and blinking in longstanding facial palsy patients.
Dhooghe N, Brusselle M, Ureel M, Sinove Y, Vermeersch H, Blondeel P
J Plast Reconstr Aesthet Surg 2024 Feb;89:57-71. Epub 2023 Nov 24 doi: 10.1016/j.bjps.2023.11.029. PMID: 38142623

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