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Tietze syndrome

MedGen UID:: 52753
•Concept ID:: C0040213
•: Disease or Syndrome

Synonyms:	Chondropathia tuberosa; Costochondral junction syndrome; Tietze's syndrome
SNOMED CT:	Tietze disease (30128009); Cyriax's syndrome (30128009); Slipping rib syndrome (30128009); Tietze's disease (30128009); Costochondral junction syndrome (30128009); Peristernal perichondritis (30128009); Tietze's syndrome (30128009)

Monarch Initiative:	MONDO:0001858

Definition

Idiopathic painful nonsuppurative swellings of one or more costal cartilages, especially of the second rib. The anterior chest pain may mimic that of coronary artery disease. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVTietze syndrome

Pathological process
- Disease
  - Disorder by Site
    - Connective and Soft Tissue Disorder
      - Connective tissue disorder
        Cartilage disorder
        Tietze syndrome

Professional guidelines

PubMed

A Comprehensive Review of Slipping Rib Syndrome: Treatment and Management.

Gress K, Charipova K, Kassem H, Berger AA, Cornett EM, Hasoon J, Schwartz R, Kaye AD, Viswanath O, Urits I
Psychopharmacol Bull 2020 Oct 15;50(4 Suppl 1):189-196. PMID: 33633425 Free PMC Article

Evaluation and treatment of musculoskeletal chest pain.

Ayloo A, Cvengros T, Marella S
Prim Care 2013 Dec;40(4):863-87, viii. doi: 10.1016/j.pop.2013.08.007. PMID: 24209723

Costochondritis: diagnosis and treatment.

Proulx AM, Zryd TW
Am Fam Physician 2009 Sep 15;80(6):617-20. PMID: 19817327

See all (21)

Recent clinical studies

Etiology

The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial.

Elsayed HH, Ali I, Abdel-Gayed M, Warda AM, Moharram AA
J Clin Pharm Ther 2022 Dec;47(12):2279-2286. Epub 2022 Nov 28 doi: 10.1111/jcpt.13810. PMID: 36443282

Prolotherapy: An effective therapy for Tietze syndrome.

Senturk E, Sahin E, Serter S
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):975-978. doi: 10.3233/BMR-159269. PMID: 28505950

Painful Chest Wall Swellings: Tietze Syndrome or Chest Wall Tumor?

Kaplan T, Gunal N, Gulbahar G, Kocer B, Han S, Eryazgan MA, Ozsoy A, Naldoken S, Alhan A, Sakinci U
Thorac Cardiovasc Surg 2016 Apr;64(3):239-44. Epub 2015 Mar 5 doi: 10.1055/s-0035-1545261. PMID: 25742551

Imaging of sternocostoclavicular joint in spondyloarthropaties and other rheumatic conditions.

Guglielmi G, Cascavilla A, Scalzo G, Salaffi F, Grassi W
Clin Exp Rheumatol 2009 May-Jun;27(3):402-8. PMID: 19604431

Clinical syndromes of mastalgia.

Preece PE, Mansel RE, Bolton PM, Hughes LM, Baum M, Gravelle IH
Lancet 1976 Sep 25;2(7987):670-3. doi: 10.1016/s0140-6736(76)92477-6. PMID: 60528

See all (5)

Diagnosis

Trunk Injuries in Athletes.

Gundersen A, Borgstrom H, McInnis KC
Curr Sports Med Rep 2021 Mar 1;20(3):150-156. doi: 10.1249/JSR.0000000000000819. PMID: 33655996

Painful Chest Wall Swellings: Tietze Syndrome or Chest Wall Tumor?

Chest pain in focal musculoskeletal disorders.

Stochkendahl MJ, Christensen HW
Med Clin North Am 2010 Mar;94(2):259-73. doi: 10.1016/j.mcna.2010.01.007. PMID: 20380955

Imaging of sternocostoclavicular joint in spondyloarthropaties and other rheumatic conditions.

Guglielmi G, Cascavilla A, Scalzo G, Salaffi F, Grassi W
Clin Exp Rheumatol 2009 May-Jun;27(3):402-8. PMID: 19604431

Clinical syndromes of mastalgia.

Preece PE, Mansel RE, Bolton PM, Hughes LM, Baum M, Gravelle IH
Lancet 1976 Sep 25;2(7987):670-3. doi: 10.1016/s0140-6736(76)92477-6. PMID: 60528

See all (9)

Therapy

The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial.

Elsayed HH, Ali I, Abdel-Gayed M, Warda AM, Moharram AA
J Clin Pharm Ther 2022 Dec;47(12):2279-2286. Epub 2022 Nov 28 doi: 10.1111/jcpt.13810. PMID: 36443282

Ultrasound-Guided Corticosteroid Injection in a Patient With Tietze Syndrome Combined With Costochondral Joint Swelling.

Cho JY, Park D
Am J Phys Med Rehabil 2019 Jul;98(7):e71-e73. doi: 10.1097/PHM.0000000000001072. PMID: 30362978

Prolotherapy: An effective therapy for Tietze syndrome.

Senturk E, Sahin E, Serter S
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):975-978. doi: 10.3233/BMR-159269. PMID: 28505950

Chest pain in focal musculoskeletal disorders.

Stochkendahl MJ, Christensen HW
Med Clin North Am 2010 Mar;94(2):259-73. doi: 10.1016/j.mcna.2010.01.007. PMID: 20380955

See all (4)

Prognosis

Surgical Management of Medically Refractory Tietze Syndrome.

Gologorsky R, Hornik B, Velotta J
Ann Thorac Surg 2017 Dec;104(6):e443-e445. doi: 10.1016/j.athoracsur.2017.07.035. PMID: 29153814

Non-Hodgkin's lymphoma at the medial clavicular head mimicking Tietze Syndrome.

Jeon IH, Jeong WJ, Yi JH, Kim HJ, Park IH
Rheumatol Int 2012 Aug;32(8):2531-4. Epub 2010 Dec 8 doi: 10.1007/s00296-010-1397-2. PMID: 21140267

See all (2)

Clinical prediction guides

The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial.

Elsayed HH, Ali I, Abdel-Gayed M, Warda AM, Moharram AA
J Clin Pharm Ther 2022 Dec;47(12):2279-2286. Epub 2022 Nov 28 doi: 10.1111/jcpt.13810. PMID: 36443282

Prolotherapy: An effective therapy for Tietze syndrome.

Senturk E, Sahin E, Serter S
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):975-978. doi: 10.3233/BMR-159269. PMID: 28505950

Non-Hodgkin's lymphoma at the medial clavicular head mimicking Tietze Syndrome.

Jeon IH, Jeong WJ, Yi JH, Kim HJ, Park IH
Rheumatol Int 2012 Aug;32(8):2531-4. Epub 2010 Dec 8 doi: 10.1007/s00296-010-1397-2. PMID: 21140267

Imaging of sternocostoclavicular joint in spondyloarthropaties and other rheumatic conditions.

Guglielmi G, Cascavilla A, Scalzo G, Salaffi F, Grassi W
Clin Exp Rheumatol 2009 May-Jun;27(3):402-8. PMID: 19604431

CT observation of rib abnormalities: spectrum of findings.

Edelstein G, Levitt RG, Slaker DP, Murphy WA
J Comput Assist Tomogr 1985 Jan-Feb;9(1):65-72. doi: 10.1097/00004728-198501000-00014. PMID: 3968282

See all (5)