U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pulmonary necrosis

MedGen UID:
538624
•Concept ID:
C0264517
•
Disease or Syndrome
SNOMED CT: Pulmonary necrosis (7159003)
 
HPO: HP:0033243

Definition

Cellular death affecting one or more parts of the lung. Necrosis is caused by diverse external and internal factors which result in the unregulated digestion of cell components. [from HPO]

Professional guidelines

PubMed

Diagnosis and Treatment of Pulmonary Sarcoidosis: A Review.
Belperio JA, Shaikh F, Abtin FG, Fishbein MC, Weigt SS, Saggar R, Lynch JP 3rd
JAMA 2022 Mar 1;327(9):856-867. doi: 10.1001/jama.2022.1570. PMID: 35230389
Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment.
Bradshaw MJ, Pawate S, Koth LL, Cho TA, Gelfand JM
Neurol Neuroimmunol Neuroinflamm 2021 Nov;8(6) Epub 2021 Oct 4 doi: 10.1212/NXI.0000000000001084. PMID: 34607912Free PMC Article
Pulmonary arterial hypertension: pathogenesis and clinical management.
Thenappan T, Ormiston ML, Ryan JJ, Archer SL
BMJ 2018 Mar 14;360:j5492. doi: 10.1136/bmj.j5492. PMID: 29540357Free PMC Article

Recent clinical studies

Etiology

Debate 2: Is the Management of Childhood Empyema Primarily Medical, or Surgical?
Menon P
Indian J Pediatr 2023 Sep;90(9):915-919. Epub 2023 May 15 doi: 10.1007/s12098-023-04589-7. PMID: 37184715
Differences of clinical features and prognosis between Mycoplasma pneumoniae necrotizing pneumonia and non-Mycoplasma pneumoniae necrotizing pneumonia in children.
Yang B, Zhang W, Gu W, Zhang X, Wang M, Huang L, Zhu C, Yan Y, Ji W, Ni H, Chen Z
BMC Infect Dis 2021 Aug 10;21(1):797. doi: 10.1186/s12879-021-06469-x. PMID: 34376156Free PMC Article
The clinical characteristics and risk factors for necrotizing pneumonia caused by Mycoplasma pneumoniae in children.
Zheng B, Zhao J, Cao L
BMC Infect Dis 2020 Jun 1;20(1):391. doi: 10.1186/s12879-020-05110-7. PMID: 32487034Free PMC Article
Surgical therapy for necrotizing pneumonia and lung gangrene.
Schweigert M, Dubecz A, Beron M, Ofner D, Stein HJ
Thorac Cardiovasc Surg 2013 Oct;61(7):636-41. Epub 2012 Oct 3 doi: 10.1055/s-0032-1311551. PMID: 23034873
Unusual radiologic findings in the thorax after radiation therapy.
Mesurolle B, Qanadli SD, Merad M, Mignon F, Baldeyrou P, Tardivon A, Lacombe P, Vanel D
Radiographics 2000 Jan-Feb;20(1):67-81. doi: 10.1148/radiographics.20.1.g00ja1167. PMID: 10682772

Diagnosis

Staphylococcus aureus Community-acquired Pneumonia in Children After 13-Valent Pneumococcal Vaccination (2008-2018): Epidemiology, Clinical Characteristics and Outcomes.
Aguilera-Alonso D, Kirchschläger Nieto S, Ara Montojo MF, Sanz Santaeufemia FJ, Saavedra-Lozano J, Soto B, Caminoa MB, Berzosa A, Prieto Tato L, Cercenado E, Tagarro A, Molina Arana D, Alonso Sanz M, Romero Gómez MP, Chaves Sánchez F, Baquero-Artigao F
Pediatr Infect Dis J 2022 May 1;41(5):e235-e242. doi: 10.1097/INF.0000000000003503. PMID: 35333816
Differences of clinical features and prognosis between Mycoplasma pneumoniae necrotizing pneumonia and non-Mycoplasma pneumoniae necrotizing pneumonia in children.
Yang B, Zhang W, Gu W, Zhang X, Wang M, Huang L, Zhu C, Yan Y, Ji W, Ni H, Chen Z
BMC Infect Dis 2021 Aug 10;21(1):797. doi: 10.1186/s12879-021-06469-x. PMID: 34376156Free PMC Article
The clinical characteristics and risk factors for necrotizing pneumonia caused by Mycoplasma pneumoniae in children.
Zheng B, Zhao J, Cao L
BMC Infect Dis 2020 Jun 1;20(1):391. doi: 10.1186/s12879-020-05110-7. PMID: 32487034Free PMC Article
Fulminant myocarditis and pulmonary cavity lesion induced by disseminated mucormycosis in a chronic hemodialysis patient: Report of an autopsied case.
Fujisawa Y, Hara S, Zoshima T, Maekawa N, Inoue D, Sasaki M, Gamou T, Nagata Y, Hayashi K, Takeji A, Ito K, Mizushima I, Fujii H, Kawano M
Pathol Int 2020 Aug;70(8):557-562. Epub 2020 Apr 29 doi: 10.1111/pin.12943. PMID: 32350952
Unusual radiologic findings in the thorax after radiation therapy.
Mesurolle B, Qanadli SD, Merad M, Mignon F, Baldeyrou P, Tardivon A, Lacombe P, Vanel D
Radiographics 2000 Jan-Feb;20(1):67-81. doi: 10.1148/radiographics.20.1.g00ja1167. PMID: 10682772

Therapy

Staphylococcus aureus Community-acquired Pneumonia in Children After 13-Valent Pneumococcal Vaccination (2008-2018): Epidemiology, Clinical Characteristics and Outcomes.
Aguilera-Alonso D, Kirchschläger Nieto S, Ara Montojo MF, Sanz Santaeufemia FJ, Saavedra-Lozano J, Soto B, Caminoa MB, Berzosa A, Prieto Tato L, Cercenado E, Tagarro A, Molina Arana D, Alonso Sanz M, Romero Gómez MP, Chaves Sánchez F, Baquero-Artigao F
Pediatr Infect Dis J 2022 May 1;41(5):e235-e242. doi: 10.1097/INF.0000000000003503. PMID: 35333816
The clinical characteristics and risk factors for necrotizing pneumonia caused by Mycoplasma pneumoniae in children.
Zheng B, Zhao J, Cao L
BMC Infect Dis 2020 Jun 1;20(1):391. doi: 10.1186/s12879-020-05110-7. PMID: 32487034Free PMC Article
Fulminant myocarditis and pulmonary cavity lesion induced by disseminated mucormycosis in a chronic hemodialysis patient: Report of an autopsied case.
Fujisawa Y, Hara S, Zoshima T, Maekawa N, Inoue D, Sasaki M, Gamou T, Nagata Y, Hayashi K, Takeji A, Ito K, Mizushima I, Fujii H, Kawano M
Pathol Int 2020 Aug;70(8):557-562. Epub 2020 Apr 29 doi: 10.1111/pin.12943. PMID: 32350952
Surgical therapy for necrotizing pneumonia and lung gangrene.
Schweigert M, Dubecz A, Beron M, Ofner D, Stein HJ
Thorac Cardiovasc Surg 2013 Oct;61(7):636-41. Epub 2012 Oct 3 doi: 10.1055/s-0032-1311551. PMID: 23034873
Surgical treatment of children with necrotizing pneumonia.
Westphal FL, Lima LC, Netto JC, Tavares E, Andrade Ede O, Silva Mdos S
J Bras Pneumol 2010 Nov-Dec;36(6):716-23. PMID: 21225174

Prognosis

Differences of clinical features and prognosis between Mycoplasma pneumoniae necrotizing pneumonia and non-Mycoplasma pneumoniae necrotizing pneumonia in children.
Yang B, Zhang W, Gu W, Zhang X, Wang M, Huang L, Zhu C, Yan Y, Ji W, Ni H, Chen Z
BMC Infect Dis 2021 Aug 10;21(1):797. doi: 10.1186/s12879-021-06469-x. PMID: 34376156Free PMC Article
The clinical characteristics and risk factors for necrotizing pneumonia caused by Mycoplasma pneumoniae in children.
Zheng B, Zhao J, Cao L
BMC Infect Dis 2020 Jun 1;20(1):391. doi: 10.1186/s12879-020-05110-7. PMID: 32487034Free PMC Article
Fatal Invasive Pulmonary Aspergillosis Associated with Nonspecific Interstitial Pneumonia: An Autopsy Case Report.
Matsuyama H, Miyoshi S, Sugino K, Ota H, Toyoda Y, Nihonyanagi Y, Shibuya K, Homma S
Intern Med 2018;57(24):3619-3624. Epub 2018 Dec 15 doi: 10.2169/internalmedicine.1144-18. PMID: 30555119Free PMC Article
Fatal case of donor-derived colistin-resistant carbapenemase-producing Klebsiella pneumoniae transmission in cardiac transplantation.
Galvão LM, Oliveira APR, Ibanês AS, Monteiro J, Inoue F, Dantas DC, Sanchez F, Santos DW, Abboud CS
Braz J Infect Dis 2018 May-Jun;22(3):235-238. Epub 2018 May 26 doi: 10.1016/j.bjid.2018.04.005. PMID: 29806996Free PMC Article
A case of rapidly progressive necrotizing pneumonia caused by community-acquired methicillin-resistant Staphylococcus aureus.
Dickson RP, Martinez SM, Ortiz JR
Respir Care 2008 Sep;53(9):1223-6. PMID: 18718042

Clinical prediction guides

Differences of clinical features and prognosis between Mycoplasma pneumoniae necrotizing pneumonia and non-Mycoplasma pneumoniae necrotizing pneumonia in children.
Yang B, Zhang W, Gu W, Zhang X, Wang M, Huang L, Zhu C, Yan Y, Ji W, Ni H, Chen Z
BMC Infect Dis 2021 Aug 10;21(1):797. doi: 10.1186/s12879-021-06469-x. PMID: 34376156Free PMC Article
The clinical characteristics and risk factors for necrotizing pneumonia caused by Mycoplasma pneumoniae in children.
Zheng B, Zhao J, Cao L
BMC Infect Dis 2020 Jun 1;20(1):391. doi: 10.1186/s12879-020-05110-7. PMID: 32487034Free PMC Article
A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis.
Amaral EP, Costa DL, Namasivayam S, Riteau N, Kamenyeva O, Mittereder L, Mayer-Barber KD, Andrade BB, Sher A
J Exp Med 2019 Mar 4;216(3):556-570. Epub 2019 Feb 20 doi: 10.1084/jem.20181776. PMID: 30787033Free PMC Article
Susceptibility of openbill storks (Anastomius oscitans) to highly pathogenic avian influenza virus subtype H5N1.
Chaichoun K, Wiriyarat W, Phonaknguen R, Sariya L, Taowan NA, Chakritbudsabong W, Chaisilp N, Eiam-ampai K, Phuttavatana P, Ratanakorn P
Southeast Asian J Trop Med Public Health 2013 Sep;44(5):799-809. PMID: 24437315
Predictors of surgical outcome for complicated pneumonia in children: impact of bacterial virulence.
Margenthaler JA, Weber TR, Keller MS
World J Surg 2004 Jan;28(1):87-91. Epub 2003 Nov 26 doi: 10.1007/s00268-003-7149-7. PMID: 14639494

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...