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Hypoglossal nerve disorder

MedGen UID:
57513
•Concept ID:
C0152181
•
Disease or Syndrome
Synonym: Hypoglossal nerve disease
SNOMED CT: Disorders of the twelfth cranial nerve (24777009); Hypoglossal nerve lesion (24777009); Disorders of the XIIth cranial nerve (24777009); Hypoglossal nerve disorder (24777009); Disorder of hypoglossal nerve (24777009); Disorder of the twelfth cranial nerve (24777009)
 
Monarch Initiative: MONDO:0001810

Definition

A non-neoplastic or neoplastic disorder affecting the hypoglossal nerve (twelfth cranial nerve). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoglossal nerve disorder

Professional guidelines

PubMed

Diagnosis and management of hypoglossal nerve-derived schwannoma in the floor of mouth: a case series.
Zhong J, Zhou Z, Hu Y, Zhao T, Yao Y, Zhong L, Zhu D
BMC Oral Health 2022 Jun 29;22(1):265. doi: 10.1186/s12903-022-02302-2. PMID: 35768820Free PMC Article
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.
Randerath W, Verbraecken J, de Raaff CAL, Hedner J, Herkenrath S, Hohenhorst W, Jakob T, Marrone O, Marklund M, McNicholas WT, Morgan RL, Pepin JL, Schiza S, Skoetz N, Smyth D, Steier J, Tonia T, Trzepizur W, van Mechelen PH, Wijkstra P
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Nov 30 doi: 10.1183/16000617.0200-2021. PMID: 34853097Free PMC Article
Recent developments in the diagnosis and treatment of obstructive sleep apnea : English version.
Stuck BA, Maurer JT
HNO 2017 Jan;65(Suppl 1):13-18. doi: 10.1007/s00106-016-0176-0. PMID: 27299890

Recent clinical studies

Etiology

Obstructive Sleep Apnea.
Johnson KG
Continuum (Minneap Minn) 2023 Aug 1;29(4):1071-1091. doi: 10.1212/CON.0000000000001264. PMID: 37590823
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.
Randerath W, Verbraecken J, de Raaff CAL, Hedner J, Herkenrath S, Hohenhorst W, Jakob T, Marrone O, Marklund M, McNicholas WT, Morgan RL, Pepin JL, Schiza S, Skoetz N, Smyth D, Steier J, Tonia T, Trzepizur W, van Mechelen PH, Wijkstra P
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Nov 30 doi: 10.1183/16000617.0200-2021. PMID: 34853097Free PMC Article
The Hypoglossal Nerve Stimulation as a Novel Therapy for Treating Obstructive Sleep Apnea-A Literature Review.
Mashaqi S, Patel SI, Combs D, Estep L, Helmick S, Machamer J, Parthasarathy S
Int J Environ Res Public Health 2021 Feb 9;18(4) doi: 10.3390/ijerph18041642. PMID: 33572156Free PMC Article
Effect of Multilevel Upper Airway Surgery vs Medical Management on the Apnea-Hypopnea Index and Patient-Reported Daytime Sleepiness Among Patients With Moderate or Severe Obstructive Sleep Apnea: The SAMS Randomized Clinical Trial.
MacKay S, Carney AS, Catcheside PG, Chai-Coetzer CL, Chia M, Cistulli PA, Hodge JC, Jones A, Kaambwa B, Lewis R, Ooi EH, Pinczel AJ, McArdle N, Rees G, Singh B, Stow N, Weaver EM, Woodman RJ, Woods CM, Yeo A, McEvoy RD
JAMA 2020 Sep 22;324(12):1168-1179. doi: 10.1001/jama.2020.14265. PMID: 32886102Free PMC Article
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article

Diagnosis

Obstructive Sleep Apnea.
Johnson KG
Continuum (Minneap Minn) 2023 Aug 1;29(4):1071-1091. doi: 10.1212/CON.0000000000001264. PMID: 37590823
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.
Randerath W, Verbraecken J, de Raaff CAL, Hedner J, Herkenrath S, Hohenhorst W, Jakob T, Marrone O, Marklund M, McNicholas WT, Morgan RL, Pepin JL, Schiza S, Skoetz N, Smyth D, Steier J, Tonia T, Trzepizur W, van Mechelen PH, Wijkstra P
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Nov 30 doi: 10.1183/16000617.0200-2021. PMID: 34853097Free PMC Article
Lower cranial nerve syndromes: a review.
Gutierrez S, Warner T, McCormack E, Werner C, Mathkour M, Iwanaga J, Uz A, Dumont AS, Tubbs RS
Neurosurg Rev 2021 Jun;44(3):1345-1355. Epub 2020 Jul 8 doi: 10.1007/s10143-020-01344-w. PMID: 32638140
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Neck-Tongue Syndrome.
Hu N, Dougherty C
Curr Pain Headache Rep 2016 Apr;20(4):27. doi: 10.1007/s11916-016-0555-y. PMID: 26984539

Therapy

Novel avenues to approach non-CPAP therapy and implement comprehensive obstructive sleep apnoea care.
Pépin JL, Eastwood P, Eckert DJ
Eur Respir J 2022 Jun;59(6) Epub 2022 Jun 2 doi: 10.1183/13993003.01788-2021. PMID: 34824053
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.
Randerath W, Verbraecken J, de Raaff CAL, Hedner J, Herkenrath S, Hohenhorst W, Jakob T, Marrone O, Marklund M, McNicholas WT, Morgan RL, Pepin JL, Schiza S, Skoetz N, Smyth D, Steier J, Tonia T, Trzepizur W, van Mechelen PH, Wijkstra P
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Nov 30 doi: 10.1183/16000617.0200-2021. PMID: 34853097Free PMC Article
Effect of Multilevel Upper Airway Surgery vs Medical Management on the Apnea-Hypopnea Index and Patient-Reported Daytime Sleepiness Among Patients With Moderate or Severe Obstructive Sleep Apnea: The SAMS Randomized Clinical Trial.
MacKay S, Carney AS, Catcheside PG, Chai-Coetzer CL, Chia M, Cistulli PA, Hodge JC, Jones A, Kaambwa B, Lewis R, Ooi EH, Pinczel AJ, McArdle N, Rees G, Singh B, Stow N, Weaver EM, Woodman RJ, Woods CM, Yeo A, McEvoy RD
JAMA 2020 Sep 22;324(12):1168-1179. doi: 10.1001/jama.2020.14265. PMID: 32886102Free PMC Article
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Cranial Nerve Injury After Carotid Endarterectomy: Incidence, Risk Factors, and Time Trends.
Kakisis JD, Antonopoulos CN, Mantas G, Moulakakis KG, Sfyroeras G, Geroulakos G
Eur J Vasc Endovasc Surg 2017 Mar;53(3):320-335. Epub 2017 Jan 21 doi: 10.1016/j.ejvs.2016.12.026. PMID: 28117240

Prognosis

Lower cranial nerve syndromes: a review.
Gutierrez S, Warner T, McCormack E, Werner C, Mathkour M, Iwanaga J, Uz A, Dumont AS, Tubbs RS
Neurosurg Rev 2021 Jun;44(3):1345-1355. Epub 2020 Jul 8 doi: 10.1007/s10143-020-01344-w. PMID: 32638140
Imaging Features of isolated hypoglossal nerve palsy.
Guarnizo A, Glikstein R, Torres C
J Neuroradiol 2020 Mar;47(2):136-150. Epub 2019 Apr 26 doi: 10.1016/j.neurad.2019.04.006. PMID: 31034896
Cranial Nerve Injury After Carotid Endarterectomy: Incidence, Risk Factors, and Time Trends.
Kakisis JD, Antonopoulos CN, Mantas G, Moulakakis KG, Sfyroeras G, Geroulakos G
Eur J Vasc Endovasc Surg 2017 Mar;53(3):320-335. Epub 2017 Jan 21 doi: 10.1016/j.ejvs.2016.12.026. PMID: 28117240
Cranial Nerve Disorders in Children: MR Imaging Findings.
Hwang JY, Yoon HK, Lee JH, Yoon HM, Jung AY, Cho YA, Lee JS, Yoon CH
Radiographics 2016 Jul-Aug;36(4):1178-94. doi: 10.1148/rg.2016150163. PMID: 27399242
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783

Clinical prediction guides

Association between anxiety, depression, and emotional distress and hypoglossal nerve stimulator adherence.
Rosenthal ME, Lyons MM, Schweller J, Yildiz VO, Chio EG, Khan MS
Sleep Breath 2022 Mar;26(1):141-147. Epub 2021 Apr 15 doi: 10.1007/s11325-021-02366-4. PMID: 33856642
Effect of Multilevel Upper Airway Surgery vs Medical Management on the Apnea-Hypopnea Index and Patient-Reported Daytime Sleepiness Among Patients With Moderate or Severe Obstructive Sleep Apnea: The SAMS Randomized Clinical Trial.
MacKay S, Carney AS, Catcheside PG, Chai-Coetzer CL, Chia M, Cistulli PA, Hodge JC, Jones A, Kaambwa B, Lewis R, Ooi EH, Pinczel AJ, McArdle N, Rees G, Singh B, Stow N, Weaver EM, Woodman RJ, Woods CM, Yeo A, McEvoy RD
JAMA 2020 Sep 22;324(12):1168-1179. doi: 10.1001/jama.2020.14265. PMID: 32886102Free PMC Article
Hypoglossal Nerve: Anatomy, Anatomical Variations Comorbidities and Clinical Significance.
Manoli A, Ploumidou K, Georgopapadakos N, Stratzias P, Skandalakis PN, Angelis S, Apostolopoulos AP, Filippou DK
J Long Term Eff Med Implants 2019;29(3):197-203. doi: 10.1615/JLongTermEffMedImplants.2020033230. PMID: 32478990
Predictive Success Factors in Selective Upper Airway Stimulation.
Heiser C, Hofauer B
ORL J Otorhinolaryngol Relat Spec 2017;79(1-2):121-128. Epub 2017 Feb 24 doi: 10.1159/000455728. PMID: 28231591
Trigeminal neuropathy--new observations.
Jannetta PJ, Robbins LJ
Neurosurgery 1980 Oct;7(4):347-51. doi: 10.1227/00006123-198010000-00006. PMID: 6969369

Recent systematic reviews

Surgical Management of Craniovertebral Junction Schwannomas: A Systematic Review.
Palmisciano P, Ferini G, Watanabe G, Conching A, Ogasawara C, Scalia G, Bin-Alamer O, Haider AS, Passanisi M, Maugeri R, Hoz SS, Baldoncini M, Campero A, Salvati M, Cohen-Gadol AA, Umana GE
Curr Oncol 2022 Jul 9;29(7):4842-4855. doi: 10.3390/curroncol29070384. PMID: 35877244Free PMC Article
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.
Randerath W, Verbraecken J, de Raaff CAL, Hedner J, Herkenrath S, Hohenhorst W, Jakob T, Marrone O, Marklund M, McNicholas WT, Morgan RL, Pepin JL, Schiza S, Skoetz N, Smyth D, Steier J, Tonia T, Trzepizur W, van Mechelen PH, Wijkstra P
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Nov 30 doi: 10.1183/16000617.0200-2021. PMID: 34853097Free PMC Article
Petrous Internal Carotid Artery Aneurysm: A Systematic Review.
Murai Y, Shirokane K, Kitamura T, Tateyama K, Matano F, Mizunari T, Morita A
J Nippon Med Sch 2020 Sep 9;87(4):172-183. Epub 2020 Mar 31 doi: 10.1272/jnms.JNMS.2020_87-407. PMID: 32238731
Hypoglossal schwannomas: A systematic review of the literature.
Bindal S, El Ahmadieh TY, Plitt A, Aoun SG, Neeley OJ, El Tecle NE, Barnett S, Gluf W
J Clin Neurosci 2019 Apr;62:162-173. Epub 2018 Nov 22 doi: 10.1016/j.jocn.2018.11.037. PMID: 30472335
Surgical Treatment of OSA on Cardiovascular Outcomes: A Systematic Review.
Halle TR, Oh MS, Collop NA, Quyyumi AA, Bliwise DL, Dedhia RC
Chest 2017 Dec;152(6):1214-1229. Epub 2017 Sep 18 doi: 10.1016/j.chest.2017.09.004. PMID: 28923761

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