U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Aseptic necrosis of head of humerus

MedGen UID:
57635
•Concept ID:
C0158449
•
Disease or Syndrome
Synonym: Aseptic Necrosis of Head of Humerus
SNOMED CT: Aseptic necrosis of head of humerus (83453001)

Definition

Aseptic necrosis involving the head of the humerus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAseptic necrosis of head of humerus

Professional guidelines

PubMed

Aseptic osteonecrosis of the shoulder: Etiologies, diagnosis and medical management.
Lancigu R, Rony L
Morphologie 2021 Jun;105(349):148-154. Epub 2021 Jan 21 doi: 10.1016/j.morpho.2020.12.010. PMID: 33485780
Osteonecrosis of the Upper Extremity: MRI-Based Zonal Patterns and Differential Diagnosis.
Schmitt R, Kalb KH, Christopoulos G, Grunz JP
Semin Musculoskelet Radiol 2019 Oct;23(5):523-533. Epub 2019 Sep 25 doi: 10.1055/s-0039-1695719. PMID: 31556087
Surgical management of osteonecrosis of the humeral head: a systematic review.
Franceschi F, Franceschetti E, Paciotti M, Torre G, Samuelsson K, Papalia R, Karlsson J, Denaro V
Knee Surg Sports Traumatol Arthrosc 2017 Oct;25(10):3270-3278. Epub 2016 May 19 doi: 10.1007/s00167-016-4169-z. PMID: 27198139

Recent clinical studies

Etiology

ACR Appropriateness Criteria® Osteonecrosis: 2022 Update.
Expert Panel on Musculoskeletal Imaging, Ha AS, Chang EY, Bartolotta RJ, Bucknor MD, Chen KC, Ellis HB Jr, Flug J, Leschied JR, Ross AB, Sharma A, Thomas JM, Beaman FD
J Am Coll Radiol 2022 Nov;19(11S):S409-S416. doi: 10.1016/j.jacr.2022.09.009. PMID: 36436966
Aseptic osteonecrosis of the shoulder: Etiologies, diagnosis and medical management.
Lancigu R, Rony L
Morphologie 2021 Jun;105(349):148-154. Epub 2021 Jan 21 doi: 10.1016/j.morpho.2020.12.010. PMID: 33485780
Effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture: an update systematic review and meta-analysis.
Shi X, Liu H, Xing R, Mei W, Zhang L, Ding L, Huang Z, Wang P
J Orthop Surg Res 2019 Aug 30;14(1):285. doi: 10.1186/s13018-019-1345-0. PMID: 31470878Free PMC Article
Surgical management of osteonecrosis of the humeral head: a systematic review.
Franceschi F, Franceschetti E, Paciotti M, Torre G, Samuelsson K, Papalia R, Karlsson J, Denaro V
Knee Surg Sports Traumatol Arthrosc 2017 Oct;25(10):3270-3278. Epub 2016 May 19 doi: 10.1007/s00167-016-4169-z. PMID: 27198139
Osteonecrosis.
Pavelka K
Baillieres Best Pract Res Clin Rheumatol 2000 Jun;14(2):399-414. doi: 10.1053/berh.2000.0072. PMID: 10925752

Diagnosis

Diagnosis and treatment of avascular necrosis of the humeral head: Current concepts.
Lee WQ, Lie HM, Lie DTT
J ISAKOS 2023 Apr;8(2):108-113. Epub 2022 Nov 23 doi: 10.1016/j.jisako.2022.11.002. PMID: 36435432
Surgical treatments of atraumatic avascular necrosis of the shoulder.
Le Coz P, Herve A, Thomazeau H
Morphologie 2021 Jun;105(349):155-161. Epub 2021 Mar 20 doi: 10.1016/j.morpho.2021.02.007. PMID: 33757693
Aseptic osteonecrosis of the shoulder: Etiologies, diagnosis and medical management.
Lancigu R, Rony L
Morphologie 2021 Jun;105(349):148-154. Epub 2021 Jan 21 doi: 10.1016/j.morpho.2020.12.010. PMID: 33485780
Surgical management of osteonecrosis of the humeral head: a systematic review.
Franceschi F, Franceschetti E, Paciotti M, Torre G, Samuelsson K, Papalia R, Karlsson J, Denaro V
Knee Surg Sports Traumatol Arthrosc 2017 Oct;25(10):3270-3278. Epub 2016 May 19 doi: 10.1007/s00167-016-4169-z. PMID: 27198139
Osteonecrosis.
Pavelka K
Baillieres Best Pract Res Clin Rheumatol 2000 Jun;14(2):399-414. doi: 10.1053/berh.2000.0072. PMID: 10925752

Therapy

Incidence of avascular necrosis following biceps tenodesis during proximal humerus open reduction and internal fixation.
Mohan K, Hintze JM, Morrissey D, Molony D
Acta Orthop Belg 2021 Jun;87(2):339-346. PMID: 34529390
Effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture: an update systematic review and meta-analysis.
Shi X, Liu H, Xing R, Mei W, Zhang L, Ding L, Huang Z, Wang P
J Orthop Surg Res 2019 Aug 30;14(1):285. doi: 10.1186/s13018-019-1345-0. PMID: 31470878Free PMC Article
Post-traumatic osteonecrosis of the proximal humerus.
Patel S, Colaco HB, Elvey ME, Lee MH
Injury 2015 Oct;46(10):1878-84. Epub 2015 Jun 19 doi: 10.1016/j.injury.2015.06.026. PMID: 26113032
Osteonecrosis of the humeral head.
Harreld KL, Marker DR, Wiesler ER, Shafiq B, Mont MA
J Am Acad Orthop Surg 2009 Jun;17(6):345-55. doi: 10.5435/00124635-200906000-00003. PMID: 19474444
Pathogenesis and treatment of osteonecrosis of the shoulder.
Sarris I, Weiser R, Sotereanos DG
Orthop Clin North Am 2004 Jul;35(3):397-404, xi. doi: 10.1016/j.ocl.2004.03.004. PMID: 15271548

Prognosis

Diagnosis and treatment of avascular necrosis of the humeral head: Current concepts.
Lee WQ, Lie HM, Lie DTT
J ISAKOS 2023 Apr;8(2):108-113. Epub 2022 Nov 23 doi: 10.1016/j.jisako.2022.11.002. PMID: 36435432
Incidence of avascular necrosis following biceps tenodesis during proximal humerus open reduction and internal fixation.
Mohan K, Hintze JM, Morrissey D, Molony D
Acta Orthop Belg 2021 Jun;87(2):339-346. PMID: 34529390
Results of partial resurfacing of humeral head in patients with avascular necrosis.
Ranalletta M, Bertona A, Tanoira I, Rossi LA, Bongiovanni S, Maignón GD
Rev Esp Cir Ortop Traumatol (Engl Ed) 2019 Jan-Feb;63(1):29-34. Epub 2018 Nov 30 doi: 10.1016/j.recot.2018.08.001. PMID: 30503809
Osteonecrosis of the humeral head.
Harreld KL, Marker DR, Wiesler ER, Shafiq B, Mont MA
J Am Acad Orthop Surg 2009 Jun;17(6):345-55. doi: 10.5435/00124635-200906000-00003. PMID: 19474444
Pathogenesis and treatment of osteonecrosis of the shoulder.
Sarris I, Weiser R, Sotereanos DG
Orthop Clin North Am 2004 Jul;35(3):397-404, xi. doi: 10.1016/j.ocl.2004.03.004. PMID: 15271548

Clinical prediction guides

Diagnosis and treatment of avascular necrosis of the humeral head: Current concepts.
Lee WQ, Lie HM, Lie DTT
J ISAKOS 2023 Apr;8(2):108-113. Epub 2022 Nov 23 doi: 10.1016/j.jisako.2022.11.002. PMID: 36435432
Cell therapy for posttraumatic shoulder osteonecrosis.
Hernigou J, Bastard C, Dubory A, Zilber S, Flouzat Lachaniette CH, Rouard H, Hernigou P
Morphologie 2021 Jun;105(349):162-169. Epub 2020 Dec 9 doi: 10.1016/j.morpho.2020.11.006. PMID: 33309197
Results of partial resurfacing of humeral head in patients with avascular necrosis.
Ranalletta M, Bertona A, Tanoira I, Rossi LA, Bongiovanni S, Maignón GD
Rev Esp Cir Ortop Traumatol (Engl Ed) 2019 Jan-Feb;63(1):29-34. Epub 2018 Nov 30 doi: 10.1016/j.recot.2018.08.001. PMID: 30503809
Glenohumeral Osteoarthritis in the Young Patient.
Saltzman BM, Leroux TS, Verma NN, Romeo AA
J Am Acad Orthop Surg 2018 Sep 1;26(17):e361-e370. doi: 10.5435/JAAOS-D-16-00657. PMID: 30095514
Osteonecrosis of the humeral head.
Harreld KL, Marker DR, Wiesler ER, Shafiq B, Mont MA
J Am Acad Orthop Surg 2009 Jun;17(6):345-55. doi: 10.5435/00124635-200906000-00003. PMID: 19474444

Recent systematic reviews

Risk factors for osteonecrosis of the humeral head after internal fixation of proximal humeral fractures: a systematic review and meta-analysis.
Ou Z, Feng Q, Peng L, Zhou M, Rai S, Tang X
Arch Orthop Trauma Surg 2024 Jan;144(1):31-40. Epub 2023 Aug 11 doi: 10.1007/s00402-023-05020-8. PMID: 37566131
Core decompression is superior to nonoperative management for humeral head osteonecrosis: a systematic review.
Dubin JA, Mirkin Y, Sax OC, Monarrez R, Chen Z, Bains SS, Hameed D, Mont MA
J Shoulder Elbow Surg 2023 Oct;32(10):2192-2200. Epub 2023 May 31 doi: 10.1016/j.jse.2023.04.024. PMID: 37268284
Outcomes and complications after arthroplasty in patients with osteonecrosis of humeral head- systematic review.
Na SS, Kim DH, Choi BC, Cho CH
J Orthop Sci 2023 Jul;28(4):772-777. Epub 2022 Apr 28 doi: 10.1016/j.jos.2022.04.002. PMID: 35490079
Effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture: an update systematic review and meta-analysis.
Shi X, Liu H, Xing R, Mei W, Zhang L, Ding L, Huang Z, Wang P
J Orthop Surg Res 2019 Aug 30;14(1):285. doi: 10.1186/s13018-019-1345-0. PMID: 31470878Free PMC Article
Surgical management of osteonecrosis of the humeral head: a systematic review.
Franceschi F, Franceschetti E, Paciotti M, Torre G, Samuelsson K, Papalia R, Karlsson J, Denaro V
Knee Surg Sports Traumatol Arthrosc 2017 Oct;25(10):3270-3278. Epub 2016 May 19 doi: 10.1007/s00167-016-4169-z. PMID: 27198139

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...