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Neutrophilic eccrine hidradenitis

MedGen UID:
57922
•Concept ID:
C0162504
•
Disease or Syndrome
Synonyms: Eccrine Hidradenitides, Neutrophilic; Eccrine Hidradenitis, Neutrophilic; Hidradenitides, Neutrophilic Eccrine; Hidradenitis, Neutrophilic Eccrine; Neutrophilic Eccrine Hidradenitides; Neutrophilic Eccrine Hidradenitis
SNOMED CT: Neutrophilic eccrine hidradenitis (238754005)

Definition

Painful red or pink edematous nodules most commonly found on the palmar and/or plantar regions. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeutrophilic eccrine hidradenitis

Professional guidelines

PubMed

Characterization and Management of Amicrobial Pustulosis of the Folds, Aseptic Abscess Syndrome, Behçet Disease, Neutrophilic Eccrine Hidradenitis, and Pyostomatitis Vegetans-Pyodermatitis Vegetans.
Nguyen GH, Camilleri MJ, Wetter DA
Dermatol Clin 2024 Apr;42(2):231-245. Epub 2024 Jan 12 doi: 10.1016/j.det.2023.12.003. PMID: 38423684
Clinical Management of Cutaneous Adverse Events in Patients on Chemotherapy: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology.
Sanmartín O, Beato C, Suh-Oh HJ, Aragón I, España A, Majem M, Segura S, Gúrpide A, Botella R, Grávalos C
Actas Dermosifiliogr (Engl Ed) 2019 Jul-Aug;110(6):448-459. Epub 2019 Apr 19 doi: 10.1016/j.ad.2019.01.011. PMID: 31010573

Recent clinical studies

Etiology

Neutrophilic eccrine hidradenitis: a retrospective study.
Isaq NA, Anand N, Camilleri MJ, Mohandesi NA, Alavi A
Int J Dermatol 2023 Sep;62(9):1142-1146. Epub 2023 Jun 23 doi: 10.1111/ijd.16765. PMID: 37350432
Neutrophilic dermatoses.
Delaleu J, Lepelletier C, Calugareanu A, De Masson A, Charvet E, Petit A, Giurgea I, Amselem S, Karabina S, Jachiet M, Mahevas T, Ram-Wolff C, Vignon-Pennamen MD, Bagot M, Battistella M, Bouaziz JD
Rev Med Interne 2022 Dec;43(12):727-738. Epub 2022 Jul 20 doi: 10.1016/j.revmed.2022.06.007. PMID: 35870984
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease.
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M
J Am Acad Dermatol 2018 Dec;79(6):987-1006. Epub 2018 Apr 11 doi: 10.1016/j.jaad.2017.11.064. PMID: 29653210
Neutrophilic dermatoses: a broad spectrum of disease.
Filosa A, Filosa G
G Ital Dermatol Venereol 2018 Apr;153(2):265-272. Epub 2018 Jan 24 doi: 10.23736/S0392-0488.18.05841-8. PMID: 29368857
Neutrophilic dermatoses: Kids are not just little people.
Lee GL, Chen AY
Clin Dermatol 2017 Nov-Dec;35(6):541-554. Epub 2017 Aug 3 doi: 10.1016/j.clindermatol.2017.08.005. PMID: 29191346

Diagnosis

Neutrophilic eccrine hidradenitis: a retrospective study.
Isaq NA, Anand N, Camilleri MJ, Mohandesi NA, Alavi A
Int J Dermatol 2023 Sep;62(9):1142-1146. Epub 2023 Jun 23 doi: 10.1111/ijd.16765. PMID: 37350432
Neutrophilic dermatoses.
Delaleu J, Lepelletier C, Calugareanu A, De Masson A, Charvet E, Petit A, Giurgea I, Amselem S, Karabina S, Jachiet M, Mahevas T, Ram-Wolff C, Vignon-Pennamen MD, Bagot M, Battistella M, Bouaziz JD
Rev Med Interne 2022 Dec;43(12):727-738. Epub 2022 Jul 20 doi: 10.1016/j.revmed.2022.06.007. PMID: 35870984
Neutrophilic Eccrine Hidradenitis.
Beatty CJ, Ghareeb ER
N Engl J Med 2021 Aug 5;385(6):e19. doi: 10.1056/NEJMicm2101571. PMID: 34347955
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease.
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M
J Am Acad Dermatol 2018 Dec;79(6):987-1006. Epub 2018 Apr 11 doi: 10.1016/j.jaad.2017.11.064. PMID: 29653210
Neutrophilic dermatoses: a broad spectrum of disease.
Filosa A, Filosa G
G Ital Dermatol Venereol 2018 Apr;153(2):265-272. Epub 2018 Jan 24 doi: 10.23736/S0392-0488.18.05841-8. PMID: 29368857

Therapy

Neutrophilic Eccrine Hidradenitis.
Beatty CJ, Ghareeb ER
N Engl J Med 2021 Aug 5;385(6):e19. doi: 10.1056/NEJMicm2101571. PMID: 34347955
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease.
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M
J Am Acad Dermatol 2018 Dec;79(6):987-1006. Epub 2018 Apr 11 doi: 10.1016/j.jaad.2017.11.064. PMID: 29653210
Neutrophilic eccrine hidradenitis.
Thorisdottir K, Tomecki KJ, Bergfeld WF, Andresen SW
J Am Acad Dermatol 1993 May;28(5 Pt 1):775-7. doi: 10.1016/0190-9622(93)70090-g. PMID: 8496425
Recurrent neutrophilic eccrine hidradenitis.
Bernstein EF, Spielvogel RL, Topolsky DL
Br J Dermatol 1992 Nov;127(5):529-33. doi: 10.1111/j.1365-2133.1992.tb14854.x. PMID: 1467295
Neutrophilic eccrine hidradenitis.
Vion B, Alvero H
Dermatologica 1991;183(1):70-2. doi: 10.1159/000247641. PMID: 1769425

Prognosis

Neutrophilic eccrine hidradenitis: a retrospective study.
Isaq NA, Anand N, Camilleri MJ, Mohandesi NA, Alavi A
Int J Dermatol 2023 Sep;62(9):1142-1146. Epub 2023 Jun 23 doi: 10.1111/ijd.16765. PMID: 37350432
Clinical Management of Cutaneous Adverse Events in Patients on Chemotherapy: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology.
Sanmartín O, Beato C, Suh-Oh HJ, Aragón I, España A, Majem M, Segura S, Gúrpide A, Botella R, Grávalos C
Actas Dermosifiliogr (Engl Ed) 2019 Jul-Aug;110(6):448-459. Epub 2019 Apr 19 doi: 10.1016/j.ad.2019.01.011. PMID: 31010573
Neutrophilic dermatoses: Kids are not just little people.
Lee GL, Chen AY
Clin Dermatol 2017 Nov-Dec;35(6):541-554. Epub 2017 Aug 3 doi: 10.1016/j.clindermatol.2017.08.005. PMID: 29191346
Palmoplantar eccrine hidradenitis: three new cases and review.
Landau M, Metzker A, Gat A, Ben-Amitai D, Brenner S
Pediatr Dermatol 1998 Mar-Apr;15(2):97-102. doi: 10.1046/j.1525-1470.1998.1998015097.x. PMID: 9572690
Dapsone in prevention of recurrent neutrophilic eccrine hidradenitis.
Shear NH, Knowles SR, Shapiro L, Poldre P
J Am Acad Dermatol 1996 Nov;35(5 Pt 2):819-22. doi: 10.1016/s0190-9622(96)90092-4. PMID: 8912594

Clinical prediction guides

Neutrophilic eccrine hidradenitis in non-small cell lung cancer.
Lee SG, In SG, Shin JH, Choi GS, Kim YC
Int J Dermatol 2007 Jan;46(1):59-60. doi: 10.1111/j.1365-4632.2006.02606.x. PMID: 17214722
Imatinib mesylate and dermatology part 2: a review of the cutaneous side effects of imatinib mesylate.
Scheinfeld N
J Drugs Dermatol 2006 Mar;5(3):228-31. PMID: 16573254
Nonneoplastic disorders of the eccrine glands.
Wenzel FG, Horn TD
J Am Acad Dermatol 1998 Jan;38(1):1-17; quiz 18-20. doi: 10.1016/s0190-9622(98)70532-8. PMID: 9448199
Recurrent palmoplantar hidradenitis in children.
Rabinowitz LG, Cintra ML, Hood AF, Esterly NB
Arch Dermatol 1995 Jul;131(7):817-20. PMID: 7611798
Neutrophilic eccrine hidradenitis.
Vion B, Alvero H
Dermatologica 1991;183(1):70-2. doi: 10.1159/000247641. PMID: 1769425

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