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Gottron papules

MedGen UID:
602613
•Concept ID:
C0423781
•
Finding
Synonym: Gottron's papules
SNOMED CT: Gottron papules (247455006); Gottron's papules (247455006)
 
HPO: HP:0025508

Definition

Violaceous papules overlying the dorsal and lateral aspects of the metacarpophalangeal and proximal interphalangeal joints. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGottron papules

Professional guidelines

PubMed

Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
The diagnosis and classification of amyopathic dermatomyositis: a historical review and assessment of existing criteria.
Concha JSS, Tarazi M, Kushner CJ, Gaffney RG, Werth VP
Br J Dermatol 2019 May;180(5):1001-1008. Epub 2019 Feb 25 doi: 10.1111/bjd.17536. PMID: 30561064Free PMC Article
Innate immune-response mechanisms in dermatomyositis: an update on pathogenesis, diagnosis and treatment.
Hornung T, Wenzel J
Drugs 2014 Jun;74(9):981-98. doi: 10.1007/s40265-014-0240-6. PMID: 24939511

Recent clinical studies

Etiology

Clinical risk factors in patients with interstitial lung disease associated with anti-MDA5 autoantibodies.
Ramos-Martinez E, Rodríguez-Vega EA, Rivera-Matias PA, Falfán-Valencia R, Pérez-Rubio G, Mejia M, González-Pérez MI, Buendia-Roldán I, Mateos-Toledo HN, Serrano JR
Med Clin (Barc) 2023 Dec 22;161(12):515-522. Epub 2023 Aug 9 doi: 10.1016/j.medcli.2023.07.013. PMID: 37567825
The clinical features of juvenile dermatomyositis: A single-centre inception cohort.
Cancarini P, Nozawa T, Whitney K, Bell-Peter A, Marcuz JA, Taddio A, Guo J, Dover S, Feldman BM
Semin Arthritis Rheum 2022 Dec;57:152104. Epub 2022 Sep 25 doi: 10.1016/j.semarthrit.2022.152104. PMID: 36183479
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
Inverse Gottron papules in juvenile dermatomyositis: an under recognized clinical entity.
Jindal AK, Guleria S, Pilania RK, Bishnoi A, Vinay K, Dogra S, Suri D, Rawat A, Singh S
Rheumatol Int 2018 Jun;38(6):1153-1160. Epub 2018 May 2 doi: 10.1007/s00296-018-4038-9. PMID: 29721695
Gottron Papules and Gottron Sign with Ulceration: A Distinctive Cutaneous Feature in a Subset of Patients with Classic Dermatomyositis and Clinically Amyopathic Dermatomyositis.
Cao H, Xia Q, Pan M, Zhao X, Li X, Shi R, Zhou M, Ding X, Kuwana M, Zheng J
J Rheumatol 2016 Sep;43(9):1735-42. Epub 2016 Jun 15 doi: 10.3899/jrheum.160024. PMID: 27307530

Diagnosis

The clinical features of juvenile dermatomyositis: A single-centre inception cohort.
Cancarini P, Nozawa T, Whitney K, Bell-Peter A, Marcuz JA, Taddio A, Guo J, Dover S, Feldman BM
Semin Arthritis Rheum 2022 Dec;57:152104. Epub 2022 Sep 25 doi: 10.1016/j.semarthrit.2022.152104. PMID: 36183479
Skin Manifestation Associated With Multicentric Reticulohistiocytosis.
Yamamoto T
J Clin Rheumatol 2022 Jan 1;28(1):e234-e239. doi: 10.1097/RHU.0000000000001679. PMID: 33337805
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
The diagnosis and classification of amyopathic dermatomyositis: a historical review and assessment of existing criteria.
Concha JSS, Tarazi M, Kushner CJ, Gaffney RG, Werth VP
Br J Dermatol 2019 May;180(5):1001-1008. Epub 2019 Feb 25 doi: 10.1111/bjd.17536. PMID: 30561064Free PMC Article
Palmar Gottron papules and Gottron sign.
Vinay K, Dogra S
J Clin Rheumatol 2015 Apr;21(3):164. doi: 10.1097/RHU.0000000000000239. PMID: 25807098

Therapy

The clinical features of juvenile dermatomyositis: A single-centre inception cohort.
Cancarini P, Nozawa T, Whitney K, Bell-Peter A, Marcuz JA, Taddio A, Guo J, Dover S, Feldman BM
Semin Arthritis Rheum 2022 Dec;57:152104. Epub 2022 Sep 25 doi: 10.1016/j.semarthrit.2022.152104. PMID: 36183479
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
Juvenile dermatomyositis with IgA nephropathy: case-based review.
Mantoo MR, Tripathy SK, Phulware RH, Bagri NK, Hari P, Barwad A
Rheumatol Int 2019 Mar;39(3):577-581. Epub 2018 Dec 14 doi: 10.1007/s00296-018-4229-4. PMID: 30552457
Palmar Gottron papules and Gottron sign.
Vinay K, Dogra S
J Clin Rheumatol 2015 Apr;21(3):164. doi: 10.1097/RHU.0000000000000239. PMID: 25807098
Innate immune-response mechanisms in dermatomyositis: an update on pathogenesis, diagnosis and treatment.
Hornung T, Wenzel J
Drugs 2014 Jun;74(9):981-98. doi: 10.1007/s40265-014-0240-6. PMID: 24939511

Prognosis

The clinical features of juvenile dermatomyositis: A single-centre inception cohort.
Cancarini P, Nozawa T, Whitney K, Bell-Peter A, Marcuz JA, Taddio A, Guo J, Dover S, Feldman BM
Semin Arthritis Rheum 2022 Dec;57:152104. Epub 2022 Sep 25 doi: 10.1016/j.semarthrit.2022.152104. PMID: 36183479
Respiratory symptoms as initial manifestations of interstitial lung disease in clinically amyopathic juvenile dermatomyositis: a case report with literature review.
Xia J, Jiang G, Jin T, Shen Q, Ma Y, Wang L, Qian L
BMC Pediatr 2021 Nov 3;21(1):488. doi: 10.1186/s12887-021-02958-9. PMID: 34732158Free PMC Article
Inverse Gottron papules in juvenile dermatomyositis: an under recognized clinical entity.
Jindal AK, Guleria S, Pilania RK, Bishnoi A, Vinay K, Dogra S, Suri D, Rawat A, Singh S
Rheumatol Int 2018 Jun;38(6):1153-1160. Epub 2018 May 2 doi: 10.1007/s00296-018-4038-9. PMID: 29721695
The epidemiology of dermatomyositis in northwestern Thrace region in Turkey: epidemiology of dermatomyositis in Turkey.
Balci MA, Donmez S, Saritas F, Bas V, Pamuk ON
Rheumatol Int 2017 Sep;37(9):1519-1525. Epub 2017 Apr 6 doi: 10.1007/s00296-017-3710-9. PMID: 28386737
Gottron Papules and Gottron Sign with Ulceration: A Distinctive Cutaneous Feature in a Subset of Patients with Classic Dermatomyositis and Clinically Amyopathic Dermatomyositis.
Cao H, Xia Q, Pan M, Zhao X, Li X, Shi R, Zhou M, Ding X, Kuwana M, Zheng J
J Rheumatol 2016 Sep;43(9):1735-42. Epub 2016 Jun 15 doi: 10.3899/jrheum.160024. PMID: 27307530

Clinical prediction guides

Characteristics of patients with juvenile dermatomyositis from 2001-2021 at a tertiary care center.
Simmons E, Kazmi M, Wilson M, Kiuru M, Tartar DM
Dermatol Online J 2022 Dec 15;28(6) doi: 10.5070/D328659719. PMID: 36809089
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
Erythroderma and extensive poikiloderma - a rare initial presentation of dermatomyositis: a case report.
Herath HMMTB, Keragala BSDP, Pahalagamage SP, Janappriya GHCC, Kulatunga A, Gunasekera CN
J Med Case Rep 2018 Mar 24;12(1):83. doi: 10.1186/s13256-018-1618-y. PMID: 29571300Free PMC Article
Gottron Papules and Gottron Sign with Ulceration: A Distinctive Cutaneous Feature in a Subset of Patients with Classic Dermatomyositis and Clinically Amyopathic Dermatomyositis.
Cao H, Xia Q, Pan M, Zhao X, Li X, Shi R, Zhou M, Ding X, Kuwana M, Zheng J
J Rheumatol 2016 Sep;43(9):1735-42. Epub 2016 Jun 15 doi: 10.3899/jrheum.160024. PMID: 27307530
Paraneoplastic dermatomyositis: a study of 12 cases.
Requena C, Alfaro A, Traves V, Nagore E, Llombart B, Serra C, Martorell A, Guillén C, Sanmartín O
Actas Dermosifiliogr 2014 Sep;105(7):675-82. Epub 2014 Jan 30 doi: 10.1016/j.ad.2013.11.007. PMID: 24484630

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