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Otitis media with effusion

MedGen UID:
629314
•Concept ID:
C0456498
•
Finding
Synonyms: Fluid behind eardrum; OME; otitis media with effusion; secretory otitis Media; serous otitis Media
 
HPO: HP:0031353
Monarch Initiative: MONDO:0005892

Definition

Otitis media characterized by thick or sticky fluid behind the tympanic membrane. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOtitis media with effusion

Professional guidelines

PubMed

Clinical Practice Guideline: Tympanostomy Tubes in Children (Update).
Rosenfeld RM, Tunkel DE, Schwartz SR, Anne S, Bishop CE, Chelius DC, Hackell J, Hunter LL, Keppel KL, Kim AH, Kim TW, Levine JM, Maksimoski MT, Moore DJ, Preciado DA, Raol NP, Vaughan WK, Walker EA, Monjur TM
Otolaryngol Head Neck Surg 2022 Feb;166(1_suppl):S1-S55. doi: 10.1177/01945998211065662. PMID: 35138954
Panel 7: Otitis Media: Treatment and Complications.
Schilder AG, Marom T, Bhutta MF, Casselbrant ML, Coates H, Gisselsson-Solén M, Hall AJ, Marchisio P, Ruohola A, Venekamp RP, Mandel EM
Otolaryngol Head Neck Surg 2017 Apr;156(4_suppl):S88-S105. doi: 10.1177/0194599816633697. PMID: 28372534
Otitis media: diagnosis and treatment.
Harmes KM, Blackwood RA, Burrows HL, Cooke JM, Harrison RV, Passamani PP
Am Fam Physician 2013 Oct 1;88(7):435-40. PMID: 24134083

Curated

UK NICE Guideline (NG233), Otitis media with effusion in under 12s, 2023

Recent clinical studies

Etiology

Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan - 2022 update.
Hidaka H, Ito M, Ikeda R, Kamide Y, Kuroki H, Nakano A, Yoshida H, Takahashi H, Iino Y, Harabuchi Y, Kobayashi H
Auris Nasus Larynx 2023 Oct;50(5):655-699. Epub 2022 Dec 27 doi: 10.1016/j.anl.2022.12.004. PMID: 36577619
ADENOID SIZE IN CHILDREN WITH OTITIS MEDIA WITH EFFUSION.
Galić MZ, Klančnik M
Acta Clin Croat 2022 Feb;60(3):532-539. doi: 10.20471/acc.2021.60.03.25. PMID: 35282481Free PMC Article
International consensus (ICON) on management of otitis media with effusion in children.
Simon F, Haggard M, Rosenfeld RM, Jia H, Peer S, Calmels MN, Couloigner V, Teissier N
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Feb;135(1S):S33-S39. Epub 2018 Feb 3 doi: 10.1016/j.anorl.2017.11.009. PMID: 29398506
Otitis media with effusion.
Atkinson H, Wallis S, Coatesworth AP
Postgrad Med 2015 May;127(4):381-5. doi: 10.1080/00325481.2015.1028317. PMID: 25913597
Otitis media: diagnosis and treatment.
Harmes KM, Blackwood RA, Burrows HL, Cooke JM, Harrison RV, Passamani PP
Am Fam Physician 2013 Oct 1;88(7):435-40. PMID: 24134083

Diagnosis

Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan - 2022 update.
Hidaka H, Ito M, Ikeda R, Kamide Y, Kuroki H, Nakano A, Yoshida H, Takahashi H, Iino Y, Harabuchi Y, Kobayashi H
Auris Nasus Larynx 2023 Oct;50(5):655-699. Epub 2022 Dec 27 doi: 10.1016/j.anl.2022.12.004. PMID: 36577619
International consensus (ICON) on management of otitis media with effusion in children.
Simon F, Haggard M, Rosenfeld RM, Jia H, Peer S, Calmels MN, Couloigner V, Teissier N
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Feb;135(1S):S33-S39. Epub 2018 Feb 3 doi: 10.1016/j.anorl.2017.11.009. PMID: 29398506
Acute Otitis Media in Children.
Venekamp RP, Damoiseaux RA, Schilder AG
Am Fam Physician 2017 Jan 15;95(2):109-110. PMID: 28084706
Otitis media with effusion.
Atkinson H, Wallis S, Coatesworth AP
Postgrad Med 2015 May;127(4):381-5. doi: 10.1080/00325481.2015.1028317. PMID: 25913597
Otitis media: diagnosis and treatment.
Harmes KM, Blackwood RA, Burrows HL, Cooke JM, Harrison RV, Passamani PP
Am Fam Physician 2013 Oct 1;88(7):435-40. PMID: 24134083

Therapy

Tympanostomy Tubes or Medical Management for Recurrent Acute Otitis Media.
Hoberman A, Preciado D, Paradise JL, Chi DH, Haralam M, Block SL, Kearney DH, Bhatnagar S, Muñiz Pujalt GB, Shope TR, Martin JM, Felten DE, Kurs-Lasky M, Liu H, Yahner K, Jeong JH, Cohen NL, Czervionke B, Nagg JP, Dohar JE, Shaikh N
N Engl J Med 2021 May 13;384(19):1789-1799. doi: 10.1056/NEJMoa2027278. PMID: 33979487Free PMC Article
Antibiotics for otitis media with effusion in children.
Venekamp RP, Burton MJ, van Dongen TM, van der Heijden GJ, van Zon A, Schilder AG
Cochrane Database Syst Rev 2016 Jun 12;2016(6):CD009163. doi: 10.1002/14651858.CD009163.pub3. PMID: 27290722Free PMC Article
Interventions for adult Eustachian tube dysfunction: a systematic review.
Llewellyn A, Norman G, Harden M, Coatesworth A, Kimberling D, Schilder A, McDaid C
Health Technol Assess 2014 Jul;18(46):1-180, v-vi. doi: 10.3310/hta18460. PMID: 25029951Free PMC Article
Antibiotics for otitis media with effusion in children.
van Zon A, van der Heijden GJ, van Dongen TM, Burton MJ, Schilder AG
Cochrane Database Syst Rev 2012 Sep 12;(9):CD009163. doi: 10.1002/14651858.CD009163.pub2. PMID: 22972136
Antihistamines and/or decongestants for otitis media with effusion (OME) in children.
Griffin G, Flynn CA
Cochrane Database Syst Rev 2011 Sep 7;2011(9):CD003423. doi: 10.1002/14651858.CD003423.pub3. PMID: 21901683Free PMC Article

Prognosis

Prognostic factors of early-onset otitis media with effusion in children treated using tympanostomy.
Inoue M, Yamamoto K, Hirama M, Ogahara N, Takahashi M, Oridate N
Acta Otolaryngol 2021 Aug;141(8):742-748. Epub 2021 Aug 12 doi: 10.1080/00016489.2021.1956690. PMID: 34380359
Relation between adenoid size and otitis media with effusion.
Skoloudik L, Kalfert D, Valenta T, Chrobok V
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec;135(6):399-402. Epub 2018 Oct 2 doi: 10.1016/j.anorl.2017.11.011. PMID: 30290997
Otitis media with effusion after radiotherapy of the head and neck: a systematic review.
Christensen JG, Wessel I, Gothelf AB, Homøe P
Acta Oncol 2018 Aug;57(8):1011-1016. Epub 2018 Apr 26 doi: 10.1080/0284186X.2018.1468085. PMID: 29698103
Otitis media with effusion in children.
Williamson I
BMJ Clin Evid 2007 Aug 1;2007 PMID: 19454116Free PMC Article
Cleft palate and otitis media with effusion: a review.
Sheahan P, Blayney AW
Rev Laryngol Otol Rhinol (Bord) 2003;124(3):171-7. PMID: 14725133

Clinical prediction guides

Otitis Media and Tympanostomy Tubes.
Otteson T
Pediatr Clin North Am 2022 Apr;69(2):203-219. doi: 10.1016/j.pcl.2022.01.001. PMID: 35337534
Audiologic Profiles of Children With Otitis Media With Effusion.
Al-Salim S, Tempero RM, Johnson H, Merchant GR
Ear Hear 2021 Sep/Oct;42(5):1195-1207. doi: 10.1097/AUD.0000000000001038. PMID: 33974785Free PMC Article
Pseudo-sudden deafness.
Song JE, Sapthavee A, Cager GR, Saadia-Redleaf MI
Ann Otol Rhinol Laryngol 2012 Feb;121(2):96-9. doi: 10.1177/000348941212100204. PMID: 22397217
Tympanometry.
Onusko E
Am Fam Physician 2004 Nov 1;70(9):1713-20. PMID: 15554489
Otitis media.
Rovers MM, Schilder AG, Zielhuis GA, Rosenfeld RM
Lancet 2004 Feb 7;363(9407):465-73. doi: 10.1016/S0140-6736(04)15495-0. PMID: 14962529

Recent systematic reviews

Antibiotics for otitis media with effusion (OME) in children.
Mulvaney CA, Galbraith K, Webster KE, Rana M, Connolly R, Marom T, Daniel M, Venekamp RP, Schilder AG, MacKeith S
Cochrane Database Syst Rev 2023 Oct 23;10(10):CD015254. doi: 10.1002/14651858.CD015254.pub2. PMID: 37870130Free PMC Article
Adenoidectomy for otitis media with effusion (OME) in children.
MacKeith S, Mulvaney CA, Galbraith K, Webster KE, Paing A, Connolly R, Marom T, Daniel M, Venekamp RP, Schilder AG
Cochrane Database Syst Rev 2023 Oct 23;10(10):CD015252. doi: 10.1002/14651858.CD015252.pub2. PMID: 37870083Free PMC Article
Autoinflation for otitis media with effusion (OME) in children.
Webster KE, Mulvaney CA, Galbraith K, Rana M, Marom T, Daniel M, Venekamp RP, Schilder AG, MacKeith S
Cochrane Database Syst Rev 2023 Sep 26;9(9):CD015253. doi: 10.1002/14651858.CD015253.pub2. PMID: 37750500Free PMC Article
Hearing loss in children with otitis media with effusion: a systematic review.
Cai T, McPherson B
Int J Audiol 2017 Feb;56(2):65-76. Epub 2016 Nov 14 doi: 10.1080/14992027.2016.1250960. PMID: 27841699
Interventions for adult Eustachian tube dysfunction: a systematic review.
Llewellyn A, Norman G, Harden M, Coatesworth A, Kimberling D, Schilder A, McDaid C
Health Technol Assess 2014 Jul;18(46):1-180, v-vi. doi: 10.3310/hta18460. PMID: 25029951Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Guideline (NG233), Otitis media with effusion in under 12s, 2023

    Consumer resources

    Reviews

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