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Bradyphrenia

MedGen UID:
640666
Concept ID:
C0554976
Mental or Behavioral Dysfunction
Synonyms: Mental slowness; Slowed thinking; Slowed thoughts; Slowness of thought
SNOMED CT: Bradyphrenia (285242009)
 
HPO: HP:0031843

Definition

Abnormal slowness of thought processes. [from HPO]

Term Hierarchy

Conditions with this feature

Intellectual disability, autosomal dominant 56
MedGen UID:
1638835
Concept ID:
C4693389
Mental or Behavioral Dysfunction

Professional guidelines

PubMed

Heinonen EH, Rinne UK
Acta Neurol Scand Suppl 1989;126:103-11. doi: 10.1111/j.1600-0404.1989.tb01789.x. PMID: 2515715

Recent clinical studies

Etiology

Schönecker S, Palleis C, Franzmeier N, Katzdobler S, Ferschmann C, Schuster S, Finze A, Scheifele M, Prix C, Fietzek U, Weidinger E, Nübling G, Vöglein J, Patt M, Barthel H, Sabri O, Danek A, Höglinger GU, Brendel M, Levin J; for German Imaging Initiative for Tauopathies GII4T
Neuroimage Clin 2023;38:103402. Epub 2023 Apr 11 doi: 10.1016/j.nicl.2023.103402. PMID: 37087820Free PMC Article
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Bonelli RM, Cummings JL
Neurologist 2008 Mar;14(2):100-7. doi: 10.1097/NRL.0b013e31815b0de2. PMID: 18332839
Darvesh S, Freedman M
Brain Cogn 1996 Jul;31(2):230-49. doi: 10.1006/brcg.1996.0043. PMID: 8812000
Mayeux R, Stern Y, Sano M, Cote L, Williams JB
Neurology 1987 Jul;37(7):1130-4. doi: 10.1212/wnl.37.7.1130. PMID: 2439947

Diagnosis

Schönecker S, Palleis C, Franzmeier N, Katzdobler S, Ferschmann C, Schuster S, Finze A, Scheifele M, Prix C, Fietzek U, Weidinger E, Nübling G, Vöglein J, Patt M, Barthel H, Sabri O, Danek A, Höglinger GU, Brendel M, Levin J; for German Imaging Initiative for Tauopathies GII4T
Neuroimage Clin 2023;38:103402. Epub 2023 Apr 11 doi: 10.1016/j.nicl.2023.103402. PMID: 37087820Free PMC Article
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
DeSousa EA, Albert RH, Kalman B
Am J Alzheimers Dis Other Demen 2002 Jan-Feb;17(1):23-9. doi: 10.1177/153331750201700104. PMID: 11831417Free PMC Article
Turner MA, Moran NF, Kopelman MD
Br J Psychiatry 2002 Feb;180:148-51. doi: 10.1192/bjp.180.2.148. PMID: 11823326
Bowes SG, O'Neill CJ, Dobbs RJ, Dobbs SM, Charlett A
Age Ageing 1994 Jan;23(1):1-2. doi: 10.1093/ageing/23.1.1. PMID: 8010163

Therapy

Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Chen J, Ma W, Zhang Y, Yang LQ, Zhang Z, Wu X, Deng Z
J Nerv Ment Dis 2014 Aug;202(8):594-602. doi: 10.1097/NMD.0000000000000167. PMID: 25010105
Kehagia AA, Barker RA, Robbins TW
Lancet Neurol 2010 Dec;9(12):1200-1213. Epub 2010 Sep 27 doi: 10.1016/S1474-4422(10)70212-X. PMID: 20880750
Narabayashi H
Stereotact Funct Neurosurg 1998;70(2-4):114-21. doi: 10.1159/000029606. PMID: 9780407
Heinonen EH, Rinne UK
Acta Neurol Scand Suppl 1989;126:103-11. doi: 10.1111/j.1600-0404.1989.tb01789.x. PMID: 2515715

Prognosis

Schönecker S, Palleis C, Franzmeier N, Katzdobler S, Ferschmann C, Schuster S, Finze A, Scheifele M, Prix C, Fietzek U, Weidinger E, Nübling G, Vöglein J, Patt M, Barthel H, Sabri O, Danek A, Höglinger GU, Brendel M, Levin J; for German Imaging Initiative for Tauopathies GII4T
Neuroimage Clin 2023;38:103402. Epub 2023 Apr 11 doi: 10.1016/j.nicl.2023.103402. PMID: 37087820Free PMC Article
Vlagsma TT, Koerts J, Tucha O, Dijkstra HT, Duits AA, van Laar T, Spikman JM
J Clin Exp Neuropsychol 2016 Oct;38(8):844-52. Epub 2016 May 1 doi: 10.1080/13803395.2016.1167840. PMID: 27132647
Cheong R, Wilson RK, Cortese IC, Newman-Toker DE
Subst Abus 2006 Dec;27(4):63-7. doi: 10.1300/j465v27n04_08. PMID: 17347127
DeSousa EA, Albert RH, Kalman B
Am J Alzheimers Dis Other Demen 2002 Jan-Feb;17(1):23-9. doi: 10.1177/153331750201700104. PMID: 11831417Free PMC Article
Paulsen JS, Salmon DP, Thal LJ, Romero R, Weisstein-Jenkins C, Galasko D, Hofstetter CR, Thomas R, Grant I, Jeste DV
Neurology 2000 May 23;54(10):1965-71. doi: 10.1212/wnl.54.10.1965. PMID: 10822438

Clinical prediction guides

Schönecker S, Palleis C, Franzmeier N, Katzdobler S, Ferschmann C, Schuster S, Finze A, Scheifele M, Prix C, Fietzek U, Weidinger E, Nübling G, Vöglein J, Patt M, Barthel H, Sabri O, Danek A, Höglinger GU, Brendel M, Levin J; for German Imaging Initiative for Tauopathies GII4T
Neuroimage Clin 2023;38:103402. Epub 2023 Apr 11 doi: 10.1016/j.nicl.2023.103402. PMID: 37087820Free PMC Article
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Vlagsma TT, Koerts J, Tucha O, Dijkstra HT, Duits AA, van Laar T, Spikman JM
J Clin Exp Neuropsychol 2016 Oct;38(8):844-52. Epub 2016 May 1 doi: 10.1080/13803395.2016.1167840. PMID: 27132647
Gray C, Cantagallo A, Della Sala S, Basaglia N
Brain Inj 1998 May;12(5):429-41. doi: 10.1080/026990598122548. PMID: 9591145
Brown RG, Marsden CD
Trends Neurosci 1990 Jan;13(1):21-9. doi: 10.1016/0166-2236(90)90058-i. PMID: 1688671

Recent systematic reviews

Verbraeken R, Luykx JJ
BMC Psychiatry 2018 Oct 29;18(1):350. doi: 10.1186/s12888-018-1935-0. PMID: 30373550Free PMC Article

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