U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Proliferating trichilemmal cyst

MedGen UID:
754766
Concept ID:
C2959585
Neoplastic Process
Synonyms: Pilar Cyst; Pilar cyst; Pilar Tumor; Pilar tumor; Pilar tumour; Proliferating pilar cyst; proliferating pilar cyst; proliferating pilar cystic tumor; proliferating pilar cystic tumour; Proliferating Pilar Tumor; proliferating Pilar tumor; proliferating Pilar tumour; Proliferating Trichilemmal Cyst; proliferating trichilemmal cyst; Proliferating trichilemmal tumor; Proliferating Trichilemmal Tumor; proliferating trichilemmal tumor; proliferating trichilemmal tumour; Proliferating tricholemmal cyst; Proliferating Tricholemmal Tumor; proliferating Tricholemmal tumor; proliferating Tricholemmal tumour
SNOMED CT: Pilar tumor (128638007); Proliferating trichilemmal tumor (446023005); Pilar cyst (419093005); Proliferating trichilemmal cyst (254678009); Proliferating pilar cyst (254678009); Proliferating trichilemmal cyst (446023005); Proliferating tricholemmal cyst (446023005)
 
Monarch Initiative: MONDO:0018850
Orphanet: ORPHA492

Definition

A rare large, multinodular, usually benign, tumor that is generally located in the posterior part of the scalp in aged women (over 50 years). It first appears as a painless nodule that later grows into a solid or partially cystic tumor that is mobile over the underlying subcutaneous tissues. It can present ulceration, inflammation or even bleeding and can cause necrosis of the adjacent tissues. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProliferating trichilemmal cyst

Professional guidelines

PubMed

Seidenari S, Pellacani G, Nasti S, Tomasi A, Pastorino L, Ghiorzo P, Ruini C, Bianchi-Scarrà G, Pollio A, Mandel VD, Ponti G
Clin Genet 2013 Jul;84(1):65-9. Epub 2012 Nov 8 doi: 10.1111/cge.12040. PMID: 23061468

Recent clinical studies

Etiology

Tellechea O, Cardoso JC, Reis JP, Ramos L, Gameiro AR, Coutinho I, Baptista AP
An Bras Dermatol 2015 Nov-Dec;90(6):780-96; quiz 797-8. doi: 10.1590/abd1806-4841.20154114. PMID: 26734858Free PMC Article
Takata M, Quinn AG, Hashimoto K, Rees JL
J Invest Dermatol 1996 May;106(5):1141-4. doi: 10.1111/1523-1747.ep12340190. PMID: 8618054

Diagnosis

Valerio E, Parro FHS, Macedo MP, Pinto CAL
An Bras Dermatol 2019;94(4):452-454. Epub 2019 Oct 17 doi: 10.1590/abd1806-4841.20198199. PMID: 31644620Free PMC Article
Garetto F, Morozzo G, Morozzo U, Rosato L
G Ital Dermatol Venereol 2018 Feb;153(1):107-110. Epub 2015 Oct 1 doi: 10.23736/S0392-0488.17.04882-9. PMID: 26426376
Tellechea O, Cardoso JC, Reis JP, Ramos L, Gameiro AR, Coutinho I, Baptista AP
An Bras Dermatol 2015 Nov-Dec;90(6):780-96; quiz 797-8. doi: 10.1590/abd1806-4841.20154114. PMID: 26734858Free PMC Article
Khaled A, Kourda M, Fazaa B, Kourda J, Ben Jilani S, Kamoun MR, Zermani R
Pathologica 2011 Jun;103(3):73-6. PMID: 22007570
Weiss J, Heine M, Grimmel M, Jung EG
J Am Acad Dermatol 1995 May;32(5 Pt 2):870-3. doi: 10.1016/0190-9622(95)91550-8. PMID: 7722047

Prognosis

Leyendecker P, de Cambourg G, Mahé A, Imperiale A, Blondet C
Clin Nucl Med 2015 Jul;40(7):598-9. doi: 10.1097/RLU.0000000000000742. PMID: 25706794
Vandeweyer E, Renard N
Acta Chir Belg 2003 Oct;103(5):507-10. doi: 10.1080/00015458.2003.11679477. PMID: 14653038
Stavrianeas NG, Katoulis AC, Stratigeas NP, Karagianni IN, Patertou-Stavrianea M, Varelzidis AG
Dermatology 1997;195(2):155-8. doi: 10.1159/000245721. PMID: 9310725
Weiss J, Heine M, Grimmel M, Jung EG
J Am Acad Dermatol 1995 May;32(5 Pt 2):870-3. doi: 10.1016/0190-9622(95)91550-8. PMID: 7722047
Brownstein MH, Arluk DJ
Cancer 1981 Sep 1;48(5):1207-14. doi: 10.1002/1097-0142(19810901)48:5<1207::aid-cncr2820480526>3.0.co;2-1. PMID: 6268280

Clinical prediction guides

Juan David DO, María de Los Ángeles VA, Claudia Ileana SC, María Elisa VM
Dermatol Surg 2023 Aug 1;49(8):759-761. Epub 2023 Jul 3 doi: 10.1097/DSS.0000000000003848. PMID: 37399135
Lee DY, Han KM, Yoon JS
Medicine (Baltimore) 2023 Jun 23;102(25):e34035. doi: 10.1097/MD.0000000000034035. PMID: 37352060Free PMC Article
Kang SJ, Wojno TH, Grossniklaus HE
Am J Ophthalmol 2007 Jun;143(6):1065-7. doi: 10.1016/j.ajo.2007.02.027. PMID: 17524785
Poiares Baptista A, Garcia E Silva L, Born MC
J Cutan Pathol 1983 Jun;10(3):178-87. doi: 10.1111/j.1600-0560.1983.tb00324.x. PMID: 6863684
Brownstein MH, Arluk DJ
Cancer 1981 Sep 1;48(5):1207-14. doi: 10.1002/1097-0142(19810901)48:5<1207::aid-cncr2820480526>3.0.co;2-1. PMID: 6268280

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...