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Systemic Arterial Hypertensive Disorder

MedGen UID:
761998
•Concept ID:
C3541293
•
Disease or Syndrome

Definition

Any condition resulting in systemically elevated blood pressure that is attributed to an arterial source. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSystemic Arterial Hypertensive Disorder

Professional guidelines

PubMed

State-of-the-art evidence in the treatment of systemic sclerosis.
Pope JE, Denton CP, Johnson SR, Fernandez-Codina A, Hudson M, Nevskaya T
Nat Rev Rheumatol 2023 Apr;19(4):212-226. Epub 2023 Feb 27 doi: 10.1038/s41584-023-00909-5. PMID: 36849541Free PMC Article
Update of EULAR recommendations for the treatment of systemic sclerosis.
Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y, Distler O, Clements P, Cutolo M, Czirjak L, Damjanov N, Del Galdo F, Denton CP, Distler JHW, Foeldvari I, Figelstone K, Frerix M, Furst DE, Guiducci S, Hunzelmann N, Khanna D, Matucci-Cerinic M, Herrick AL, van den Hoogen F, van Laar JM, Riemekasten G, Silver R, Smith V, Sulli A, Tarner I, Tyndall A, Welling J, Wigley F, Valentini G, Walker UA, Zulian F, Müller-Ladner U; EUSTAR Coauthors
Ann Rheum Dis 2017 Aug;76(8):1327-1339. Epub 2016 Nov 9 doi: 10.1136/annrheumdis-2016-209909. PMID: 27941129
2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative.
van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Müller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Ellen Csuka M, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE
Ann Rheum Dis 2013 Nov;72(11):1747-55. doi: 10.1136/annrheumdis-2013-204424. PMID: 24092682

Recent clinical studies

Etiology

Pulmonary hypertension - the latest updates for physicians.
Virsinskaite R, Karia N, Kotecha T, Schreiber BE, Coghlan JG, Knight DS
Clin Med (Lond) 2023 Sep;23(5):449-454. doi: 10.7861/clinmed.2023-23.5.Cardio4. PMID: 37775164Free PMC Article
Vascular mechanisms and molecular targets in hypertensive pregnancy and preeclampsia.
Qu H, Khalil RA
Am J Physiol Heart Circ Physiol 2020 Sep 1;319(3):H661-H681. Epub 2020 Aug 7 doi: 10.1152/ajpheart.00202.2020. PMID: 32762557Free PMC Article
Sodium Intake and Hypertension.
Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G
Nutrients 2019 Aug 21;11(9) doi: 10.3390/nu11091970. PMID: 31438636Free PMC Article
Cerebral Haemodynamics: Effects of Systemic Arterial Pulsatile Function and Hypertension.
Avolio A, Kim MO, Adji A, Gangoda S, Avadhanam B, Tan I, Butlin M
Curr Hypertens Rep 2018 Mar 19;20(3):20. doi: 10.1007/s11906-018-0822-x. PMID: 29556793
Exertional dyspnoea in pulmonary arterial hypertension.
Dumitrescu D, Sitbon O, Weatherald J, Howard LS
Eur Respir Rev 2017 Sep 30;26(145) Epub 2017 Sep 6 doi: 10.1183/16000617.0039-2017. PMID: 28877974Free PMC Article

Diagnosis

Pulmonary hypertension - the latest updates for physicians.
Virsinskaite R, Karia N, Kotecha T, Schreiber BE, Coghlan JG, Knight DS
Clin Med (Lond) 2023 Sep;23(5):449-454. doi: 10.7861/clinmed.2023-23.5.Cardio4. PMID: 37775164Free PMC Article
BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.
Cuthbertson I, Morrell NW, Caruso P
Circ Res 2023 Jan 6;132(1):109-126. Epub 2023 Jan 5 doi: 10.1161/CIRCRESAHA.122.321554. PMID: 36603064
The physiological basis of pulmonary arterial hypertension.
Naeije R, Richter MJ, Rubin LJ
Eur Respir J 2022 Jun;59(6) Epub 2022 Jun 16 doi: 10.1183/13993003.02334-2021. PMID: 34737219Free PMC Article
Sodium Intake and Hypertension.
Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G
Nutrients 2019 Aug 21;11(9) doi: 10.3390/nu11091970. PMID: 31438636Free PMC Article
Definitions and diagnosis of pulmonary hypertension.
Hoeper MM, Bogaard HJ, Condliffe R, Frantz R, Khanna D, Kurzyna M, Langleben D, Manes A, Satoh T, Torres F, Wilkins MR, Badesch DB
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D42-50. doi: 10.1016/j.jacc.2013.10.032. PMID: 24355641

Therapy

Different exercise training modalities produce similar endothelial function improvements in individuals with prehypertension or hypertension: a randomized clinical trial Exercise, endothelium and blood pressure.
Pedralli ML, Marschner RA, Kollet DP, Neto SG, Eibel B, Tanaka H, Lehnen AM
Sci Rep 2020 May 6;10(1):7628. doi: 10.1038/s41598-020-64365-x. PMID: 32376984Free PMC Article
Sodium Intake and Hypertension.
Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G
Nutrients 2019 Aug 21;11(9) doi: 10.3390/nu11091970. PMID: 31438636Free PMC Article
Phosphodiesterase 5 inhibitors for pulmonary hypertension.
Barnes H, Brown Z, Burns A, Williams T
Cochrane Database Syst Rev 2019 Jan 31;1(1):CD012621. doi: 10.1002/14651858.CD012621.pub2. PMID: 30701543Free PMC Article
Renal Denervation.
Hameed MA, Dasgupta I
Adv Exp Med Biol 2017;956:261-277. doi: 10.1007/5584_2016_148. PMID: 27815927
Obstructive sleep apnea: a cardiometabolic risk in obesity and the metabolic syndrome.
Drager LF, Togeiro SM, Polotsky VY, Lorenzi-Filho G
J Am Coll Cardiol 2013 Aug 13;62(7):569-76. Epub 2013 Jun 12 doi: 10.1016/j.jacc.2013.05.045. PMID: 23770180Free PMC Article

Prognosis

Pulmonary hypertension - the latest updates for physicians.
Virsinskaite R, Karia N, Kotecha T, Schreiber BE, Coghlan JG, Knight DS
Clin Med (Lond) 2023 Sep;23(5):449-454. doi: 10.7861/clinmed.2023-23.5.Cardio4. PMID: 37775164Free PMC Article
BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.
Cuthbertson I, Morrell NW, Caruso P
Circ Res 2023 Jan 6;132(1):109-126. Epub 2023 Jan 5 doi: 10.1161/CIRCRESAHA.122.321554. PMID: 36603064
RV pressure overload: from hypertrophy to failure.
van der Bruggen CEE, Tedford RJ, Handoko ML, van der Velden J, de Man FS
Cardiovasc Res 2017 Oct 1;113(12):1423-1432. doi: 10.1093/cvr/cvx145. PMID: 28957530
Exertional dyspnoea in pulmonary arterial hypertension.
Dumitrescu D, Sitbon O, Weatherald J, Howard LS
Eur Respir Rev 2017 Sep 30;26(145) Epub 2017 Sep 6 doi: 10.1183/16000617.0039-2017. PMID: 28877974Free PMC Article
Pediatric pulmonary hypertension.
Ivy DD, Abman SH, Barst RJ, Berger RM, Bonnet D, Fleming TR, Haworth SG, Raj JU, Rosenzweig EB, Schulze Neick I, Steinhorn RH, Beghetti M
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D117-26. doi: 10.1016/j.jacc.2013.10.028. PMID: 24355636

Clinical prediction guides

BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.
Cuthbertson I, Morrell NW, Caruso P
Circ Res 2023 Jan 6;132(1):109-126. Epub 2023 Jan 5 doi: 10.1161/CIRCRESAHA.122.321554. PMID: 36603064
RV pressure overload: from hypertrophy to failure.
van der Bruggen CEE, Tedford RJ, Handoko ML, van der Velden J, de Man FS
Cardiovasc Res 2017 Oct 1;113(12):1423-1432. doi: 10.1093/cvr/cvx145. PMID: 28957530
microRNA and Pulmonary Hypertension.
Boucherat O, Potus F, Bonnet S
Adv Exp Med Biol 2015;888:237-52. doi: 10.1007/978-3-319-22671-2_12. PMID: 26663186
Nephrolithiasis and hypertension: possible links and clinical implications.
Cupisti A, D'Alessandro C, Samoni S, Meola M, Egidi MF
J Nephrol 2014 Oct;27(5):477-82. Epub 2014 Feb 28 doi: 10.1007/s40620-014-0068-x. PMID: 24577680
Definitions and diagnosis of pulmonary hypertension.
Hoeper MM, Bogaard HJ, Condliffe R, Frantz R, Khanna D, Kurzyna M, Langleben D, Manes A, Satoh T, Torres F, Wilkins MR, Badesch DB
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D42-50. doi: 10.1016/j.jacc.2013.10.032. PMID: 24355641

Recent systematic reviews

Pregnancy in patients with systemic lupus erythematosus: a systematic review.
Zhang S, Han X, Liu W, Wen Q, Wang J
Arch Gynecol Obstet 2023 Jul;308(1):63-71. Epub 2022 Aug 1 doi: 10.1007/s00404-022-06718-7. PMID: 35913558
Cardiovascular Changes in Menopause.
Nair AR, Pillai AJ, Nair N
Curr Cardiol Rev 2021;17(4):e230421187681. doi: 10.2174/1573403X16666201106141811. PMID: 33155924Free PMC Article
Phosphodiesterase 5 inhibitors for pulmonary hypertension.
Barnes H, Brown Z, Burns A, Williams T
Cochrane Database Syst Rev 2019 Jan 31;1(1):CD012621. doi: 10.1002/14651858.CD012621.pub2. PMID: 30701543Free PMC Article
Update of EULAR recommendations for the treatment of systemic sclerosis.
Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y, Distler O, Clements P, Cutolo M, Czirjak L, Damjanov N, Del Galdo F, Denton CP, Distler JHW, Foeldvari I, Figelstone K, Frerix M, Furst DE, Guiducci S, Hunzelmann N, Khanna D, Matucci-Cerinic M, Herrick AL, van den Hoogen F, van Laar JM, Riemekasten G, Silver R, Smith V, Sulli A, Tarner I, Tyndall A, Welling J, Wigley F, Valentini G, Walker UA, Zulian F, Müller-Ladner U; EUSTAR Coauthors
Ann Rheum Dis 2017 Aug;76(8):1327-1339. Epub 2016 Nov 9 doi: 10.1136/annrheumdis-2016-209909. PMID: 27941129
Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Chen W, Thomas J, Sadatsafavi M, FitzGerald JM
Lancet Respir Med 2015 Aug;3(8):631-9. Epub 2015 Jul 22 doi: 10.1016/S2213-2600(15)00241-6. PMID: 26208998

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