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Toxic polyneuropathy

MedGen UID:
78747
•Concept ID:
C0270934
•
Disease or Syndrome
Synonyms: Polyneuropathy due to toxic agents; Toxic Polyneuropathy
SNOMED CT: Toxic polyneuropathy (45600000); Polyneuropathy due to toxic agents (45600000)

Definition

Polyneuropathy that is caused by exposure to toxins. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVToxic polyneuropathy

Professional guidelines

PubMed

POEMS syndrome: 2021 Update on diagnosis, risk-stratification, and management.
Dispenzieri A
Am J Hematol 2021 Jul 1;96(7):872-888. Epub 2021 May 31 doi: 10.1002/ajh.26240. PMID: 34000085
Diagnosis and management of sensory polyneuropathy.
Gwathmey KG, Pearson KT
BMJ 2019 May 8;365:l1108. doi: 10.1136/bmj.l1108. PMID: 31068323
POEMS Syndrome: 2019 Update on diagnosis, risk-stratification, and management.
Dispenzieri A
Am J Hematol 2019 Jul;94(7):812-827. Epub 2019 May 23 doi: 10.1002/ajh.25495. PMID: 31012139

Recent clinical studies

Etiology

Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy.
Beutler AS, Kulkarni AA, Kanwar R, Klein CJ, Therneau TM, Qin R, Banck MS, Boora GK, Ruddy KJ, Wu Y, Smalley RL, Cunningham JM, Le-Lindqwister NA, Beyerlein P, Schroth GP, Windebank AJ, Züchner S, Loprinzi CL
Ann Neurol 2014 Nov;76(5):727-37. Epub 2014 Sep 17 doi: 10.1002/ana.24265. PMID: 25164601Free PMC Article
Increased expression of glial cell line-derived neurotrophic factor mRNA in muscle biopsies from patients with amyotrophic lateral sclerosis.
Grundström E, Askmark H, Lindeberg J, Nygren I, Ebendal T, Aquilonius SM
J Neurol Sci 1999 Jan 15;162(2):169-73. doi: 10.1016/s0022-510x(98)00333-5. PMID: 10202982
Peripheral nervous system and spinal cord involvement in lymphoma.
Correale J, Monteverde DA, Bueri JA, Reich EG
Acta Neurol Scand 1991 Jan;83(1):45-51. doi: 10.1111/j.1600-0404.1991.tb03957.x. PMID: 1849335
Toxic polyneuropathy of shoe workers in Italy. A clinical, neurophysiological and follow-up study.
Passero S, Battistini N, Cioni R, Giannini F, Paradiso C, Battista F, Carboncini F, Sartorelli E
Ital J Neurol Sci 1983 Dec;4(4):463-72. doi: 10.1007/BF02125628. PMID: 6674248
Toxic polyneuropathy of shoe-industry workers. A study of 122 cases.
Cianchetti C, Abbritti G, Perticoni G, Siracusa A, Curradi F
J Neurol Neurosurg Psychiatry 1976 Dec;39(12):1151-61. doi: 10.1136/jnnp.39.12.1151. PMID: 1011025Free PMC Article

Diagnosis

Peripheral neuropathy: an underreported neurologic manifestation of inflammatory bowel disease.
García-Cabo C, Morís G
Eur J Intern Med 2015 Sep;26(7):468-75. Epub 2015 Jul 23 doi: 10.1016/j.ejim.2015.07.013. PMID: 26211733
Incidence of polyneuropathy in Utrecht, the Netherlands.
Visser NA, Notermans NC, Linssen RS, van den Berg LH, Vrancken AF
Neurology 2015 Jan 20;84(3):259-64. Epub 2014 Dec 12 doi: 10.1212/WNL.0000000000001160. PMID: 25503982
Toxic polyneuropathy of shoe workers in Italy. A clinical, neurophysiological and follow-up study.
Passero S, Battistini N, Cioni R, Giannini F, Paradiso C, Battista F, Carboncini F, Sartorelli E
Ital J Neurol Sci 1983 Dec;4(4):463-72. doi: 10.1007/BF02125628. PMID: 6674248
Occupational peripheral neuropathies.
Lotti M, Becker CE, Aminoff MJ
West J Med 1982 Dec;137(6):493-8. PMID: 6299013Free PMC Article
Toxic polyneuropathy due to methyl n-butyl ketone. An industrial outbreak.
Allen N, Mendell JR, Billmaier DJ, Fontaine RE, O'Neill J
Arch Neurol 1975 Apr;32(4):209-18. doi: 10.1001/archneur.1975.00490460025001. PMID: 164846

Therapy

Peripheral neuropathy: an underreported neurologic manifestation of inflammatory bowel disease.
García-Cabo C, Morís G
Eur J Intern Med 2015 Sep;26(7):468-75. Epub 2015 Jul 23 doi: 10.1016/j.ejim.2015.07.013. PMID: 26211733
Toxicity of maduramicin.
Sharma N, Bhalla A, Varma S, Jain S, Singh S
Emerg Med J 2005 Dec;22(12):880-2. doi: 10.1136/emj.2004.020883. PMID: 16299200Free PMC Article
Shoe-makers' polyneuropathy in Italy: the aetiological problem.
Abbritti G, Siracusa A, Cianchetti C, Coli A, Curradi F, Perticoni GF, De Rosa F
Br J Ind Med 1976 May;33(2):92-9. doi: 10.1136/oem.33.2.92. PMID: 1276096Free PMC Article
Toxic polyneuropathy due to methyl n-butyl ketone. An industrial outbreak.
Allen N, Mendell JR, Billmaier DJ, Fontaine RE, O'Neill J
Arch Neurol 1975 Apr;32(4):209-18. doi: 10.1001/archneur.1975.00490460025001. PMID: 164846
Toxic polyneuropathy produced by methyl N-butyl ketone.
Mendell JR, Saida K, Ganansia MF, Jackson DB, Weiss H, Gardier RW, Chrisman C, Allen N, Couri D, O'Neill J, Marks B, Hetland L
Science 1974 Aug 30;185(4153):787-9. doi: 10.1126/science.185.4153.787. PMID: 4367263

Prognosis

Incidence of polyneuropathy in Utrecht, the Netherlands.
Visser NA, Notermans NC, Linssen RS, van den Berg LH, Vrancken AF
Neurology 2015 Jan 20;84(3):259-64. Epub 2014 Dec 12 doi: 10.1212/WNL.0000000000001160. PMID: 25503982
Toxicity of maduramicin.
Sharma N, Bhalla A, Varma S, Jain S, Singh S
Emerg Med J 2005 Dec;22(12):880-2. doi: 10.1136/emj.2004.020883. PMID: 16299200Free PMC Article
Chronic polyneuropathies in Vest-Agder, Norway.
Mygland A, Monstad P
Eur J Neurol 2001 Mar;8(2):157-65. doi: 10.1046/j.1468-1331.2001.00187.x. PMID: 11284994
Toxic polyneuropathy of shoe workers in Italy. A clinical, neurophysiological and follow-up study.
Passero S, Battistini N, Cioni R, Giannini F, Paradiso C, Battista F, Carboncini F, Sartorelli E
Ital J Neurol Sci 1983 Dec;4(4):463-72. doi: 10.1007/BF02125628. PMID: 6674248
Toxic polyneuropathy due to methyl n-butyl ketone. An industrial outbreak.
Allen N, Mendell JR, Billmaier DJ, Fontaine RE, O'Neill J
Arch Neurol 1975 Apr;32(4):209-18. doi: 10.1001/archneur.1975.00490460025001. PMID: 164846

Clinical prediction guides

Chronic polyneuropathies in Vest-Agder, Norway.
Mygland A, Monstad P
Eur J Neurol 2001 Mar;8(2):157-65. doi: 10.1046/j.1468-1331.2001.00187.x. PMID: 11284994
Toxic polyneuropathy of shoe workers in Italy. A clinical, neurophysiological and follow-up study.
Passero S, Battistini N, Cioni R, Giannini F, Paradiso C, Battista F, Carboncini F, Sartorelli E
Ital J Neurol Sci 1983 Dec;4(4):463-72. doi: 10.1007/BF02125628. PMID: 6674248
Toxic polyneuropathy due to n-hexane.
Scelsi R, Poggi P, Fera L, Gonella G
J Neurol Sci 1980 Jul;47(1):7-19. doi: 10.1016/0022-510x(80)90021-0. PMID: 6251172
Toxic polyneuropathy of shoe-industry workers. A study of 122 cases.
Cianchetti C, Abbritti G, Perticoni G, Siracusa A, Curradi F
J Neurol Neurosurg Psychiatry 1976 Dec;39(12):1151-61. doi: 10.1136/jnnp.39.12.1151. PMID: 1011025Free PMC Article
Toxic polyneuropathy produced by methyl N-butyl ketone.
Mendell JR, Saida K, Ganansia MF, Jackson DB, Weiss H, Gardier RW, Chrisman C, Allen N, Couri D, O'Neill J, Marks B, Hetland L
Science 1974 Aug 30;185(4153):787-9. doi: 10.1126/science.185.4153.787. PMID: 4367263

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