U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Polyp of ethmoidal sinus

MedGen UID:
82675
•Concept ID:
C0264248
•
Neoplastic Process
Synonyms: Ethmoid Sinus Polyp; ethmoid sinus polyp; Ethmoidal polyp; Ethmoidal Polyp; ethmoidal polyp; Ethmoidal Sinus Polyp; ethmoidal sinus polyp; Polyp of Ethmoid Sinus; polyp of ethmoid sinus; Polyp of Ethmoidal Sinus; polyp of ethmoidal sinus; Polyp of the Ethmoid Sinus; polyp of the ethmoid sinus; Polyp of the Ethmoidal Sinus; polyp of the ethmoidal sinus
SNOMED CT: Ethmoidal polyp (23966000); Polyp of ethmoidal sinus (23966000)
 
Monarch Initiative: MONDO:0021418

Definition

A polyp that arises from the ethmoid sinus mucosa. It is characterized by the presence of edematous tissue infiltrated by inflammatory cells, including eosinophils. Causes include allergic rhinitis, chronic sinusitis, and cystic fibrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolyp of ethmoidal sinus

Professional guidelines

PubMed

Evaluation of the PROPEL(®) mini sinus implant for the treatment of frontal sinus disease.
Santarelli GD, Han JK
Expert Opin Drug Deliv 2016 Dec;13(12):1789-1793. Epub 2016 Nov 6 doi: 10.1080/17425247.2016.1250740. PMID: 27758142
Nasal polyposis: an overview of differential diagnosis and treatment.
Cingi C, Demirbas D, Ural A
Recent Pat Inflamm Allergy Drug Discov 2011 Sep;5(3):241-52. doi: 10.2174/187221311797264900. PMID: 21834752
Recognition and management of sinusitis.
Evans KL
Drugs 1998 Jul;56(1):59-71. doi: 10.2165/00003495-199856010-00006. PMID: 9664199

Recent clinical studies

Etiology

Mechanisms and biomarkers of inflammatory endotypes in chronic rhinosinusitis without nasal polyps.
Klingler AI, Stevens WW, Tan BK, Peters AT, Poposki JA, Grammer LC, Welch KC, Smith SS, Conley DB, Kern RC, Schleimer RP, Kato A
J Allergy Clin Immunol 2021 Apr;147(4):1306-1317. Epub 2020 Dec 14 doi: 10.1016/j.jaci.2020.11.037. PMID: 33326802Free PMC Article
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study.
Tokunaga T, Sakashita M, Haruna T, Asaka D, Takeno S, Ikeda H, Nakayama T, Seki N, Ito S, Murata J, Sakuma Y, Yoshida N, Terada T, Morikura I, Sakaida H, Kondo K, Teraguchi K, Okano M, Otori N, Yoshikawa M, Hirakawa K, Haruna S, Himi T, Ikeda K, Ishitoya J, Iino Y, Kawata R, Kawauchi H, Kobayashi M, Yamasoba T, Miwa T, Urashima M, Tamari M, Noguchi E, Ninomiya T, Imoto Y, Morikawa T, Tomita K, Takabayashi T, Fujieda S
Allergy 2015 Aug;70(8):995-1003. Epub 2015 May 26 doi: 10.1111/all.12644. PMID: 25945591Free PMC Article
Chapter 8: Rhinosinusitis.
Georgy MS, Peters AT
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:24-27. doi: 10.2500/aap.2012.33.3538. PMID: 22794681
Rhinitis medicamentosa.
Toohill RJ, Lehman RH, Grossman TW, Belson TP
Laryngoscope 1981 Oct;91(10):1614-21. doi: 10.1288/00005537-198110000-00005. PMID: 6169966

Diagnosis

Chronic nasal dysfunction.
Jankowski R, Nguyen DT, Russel A, Toussaint B, Gallet P, Rumeau C
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Feb;135(1):41-49. Epub 2017 Dec 14 doi: 10.1016/j.anorl.2017.11.006. PMID: 29249643
Chronic Rhinosinusitis with Nasal Polyps.
Stevens WW, Schleimer RP, Kern RC
J Allergy Clin Immunol Pract 2016 Jul-Aug;4(4):565-72. doi: 10.1016/j.jaip.2016.04.012. PMID: 27393770Free PMC Article
Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study.
Tokunaga T, Sakashita M, Haruna T, Asaka D, Takeno S, Ikeda H, Nakayama T, Seki N, Ito S, Murata J, Sakuma Y, Yoshida N, Terada T, Morikura I, Sakaida H, Kondo K, Teraguchi K, Okano M, Otori N, Yoshikawa M, Hirakawa K, Haruna S, Himi T, Ikeda K, Ishitoya J, Iino Y, Kawata R, Kawauchi H, Kobayashi M, Yamasoba T, Miwa T, Urashima M, Tamari M, Noguchi E, Ninomiya T, Imoto Y, Morikawa T, Tomita K, Takabayashi T, Fujieda S
Allergy 2015 Aug;70(8):995-1003. Epub 2015 May 26 doi: 10.1111/all.12644. PMID: 25945591Free PMC Article
Chapter 8: Rhinosinusitis.
Georgy MS, Peters AT
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:24-27. doi: 10.2500/aap.2012.33.3538. PMID: 22794681
Rhinitis medicamentosa.
Toohill RJ, Lehman RH, Grossman TW, Belson TP
Laryngoscope 1981 Oct;91(10):1614-21. doi: 10.1288/00005537-198110000-00005. PMID: 6169966

Therapy

Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP.
Guo CL, Liu FF, Wang DY, Liu Z
Curr Allergy Asthma Rep 2023 Dec;23(12):703-713. Epub 2023 Nov 21 doi: 10.1007/s11882-023-01114-w. PMID: 37987873
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
On ciprofloxacin concentration in chronic rhinosinusitis.
Gameiro Dos Santos J, Figueirinhas R, Liberal JP, Almeida JC, Sousa J, Falcão A, Vicente C, Paço J, Sousa CA
Acta Otorrinolaringol Esp (Engl Ed) 2018 Jan-Feb;69(1):35-41. Epub 2017 Aug 30 doi: 10.1016/j.otorri.2017.06.008. PMID: 28859993
Steroid-dependent anosmia.
Jafek BW, Moran DT, Eller PM, Rowley JC 3rd, Jafek TB
Arch Otolaryngol Head Neck Surg 1987 May;113(5):547-9. doi: 10.1001/archotol.1987.01860050093023. PMID: 3566932
Rhinitis medicamentosa.
Toohill RJ, Lehman RH, Grossman TW, Belson TP
Laryngoscope 1981 Oct;91(10):1614-21. doi: 10.1288/00005537-198110000-00005. PMID: 6169966

Prognosis

Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP.
Guo CL, Liu FF, Wang DY, Liu Z
Curr Allergy Asthma Rep 2023 Dec;23(12):703-713. Epub 2023 Nov 21 doi: 10.1007/s11882-023-01114-w. PMID: 37987873
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
Revision endoscopic sinonasal surgery.
Cantillano P, Rubio F, Naser A, Nazar R
Acta Otorrinolaringol Esp 2017 Jan-Feb;68(1):1-8. Epub 2016 May 17 doi: 10.1016/j.otorri.2016.02.006. PMID: 27206393
Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study.
Tokunaga T, Sakashita M, Haruna T, Asaka D, Takeno S, Ikeda H, Nakayama T, Seki N, Ito S, Murata J, Sakuma Y, Yoshida N, Terada T, Morikura I, Sakaida H, Kondo K, Teraguchi K, Okano M, Otori N, Yoshikawa M, Hirakawa K, Haruna S, Himi T, Ikeda K, Ishitoya J, Iino Y, Kawata R, Kawauchi H, Kobayashi M, Yamasoba T, Miwa T, Urashima M, Tamari M, Noguchi E, Ninomiya T, Imoto Y, Morikawa T, Tomita K, Takabayashi T, Fujieda S
Allergy 2015 Aug;70(8):995-1003. Epub 2015 May 26 doi: 10.1111/all.12644. PMID: 25945591Free PMC Article
Steroid-dependent anosmia.
Jafek BW, Moran DT, Eller PM, Rowley JC 3rd, Jafek TB
Arch Otolaryngol Head Neck Surg 1987 May;113(5):547-9. doi: 10.1001/archotol.1987.01860050093023. PMID: 3566932

Clinical prediction guides

Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP.
Guo CL, Liu FF, Wang DY, Liu Z
Curr Allergy Asthma Rep 2023 Dec;23(12):703-713. Epub 2023 Nov 21 doi: 10.1007/s11882-023-01114-w. PMID: 37987873
The relationship of sinus opacification, olfaction and dupilumab efficacy in patients with CRSwNP.
Lee SE, Amin N, Mannent LP, Bachert C, Gross G, Cho SH, Praestgaard A, Siddiqui S, Nash S, Kamat S, Khan AH, Jacob Nara JA
Rhinology 2023 Dec 1;61(6):531-540. doi: 10.4193/Rhin22.220. PMID: 37453138
Woakes' syndrome.
El Fakiri MM, Lakhdar Y, Raji A
BMJ Case Rep 2019 Mar 31;12(3) doi: 10.1136/bcr-2018-229021. PMID: 30936362Free PMC Article
Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study.
Tokunaga T, Sakashita M, Haruna T, Asaka D, Takeno S, Ikeda H, Nakayama T, Seki N, Ito S, Murata J, Sakuma Y, Yoshida N, Terada T, Morikura I, Sakaida H, Kondo K, Teraguchi K, Okano M, Otori N, Yoshikawa M, Hirakawa K, Haruna S, Himi T, Ikeda K, Ishitoya J, Iino Y, Kawata R, Kawauchi H, Kobayashi M, Yamasoba T, Miwa T, Urashima M, Tamari M, Noguchi E, Ninomiya T, Imoto Y, Morikawa T, Tomita K, Takabayashi T, Fujieda S
Allergy 2015 Aug;70(8):995-1003. Epub 2015 May 26 doi: 10.1111/all.12644. PMID: 25945591Free PMC Article
Mucoceles of the frontal sinus. Clinical and therapeutical considerations.
Gavioli C, Grasso DL, Carinci F, Amoroso C, Pastore A
Minerva Stomatol 2002 Sep;51(9):385-90. PMID: 12473975

Recent systematic reviews

Efficacy of steroid-eluting stents in management of chronic rhinosinusitis after endoscopic sinus surgery: updated meta-analysis.
Goshtasbi K, Abouzari M, Abiri A, Yasaka T, Sahyouni R, Bitner B, Tajudeen BA, Kuan EC
Int Forum Allergy Rhinol 2019 Dec;9(12):1443-1450. Epub 2019 Sep 20 doi: 10.1002/alr.22443. PMID: 31539461Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...