U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Chronic viral hepatitis

MedGen UID:
82915
•Concept ID:
C0276623
•
Disease or Syndrome
Synonym: Chronic Viral Hepatitis
SNOMED CT: Chronic viral hepatitis (10295004)

Definition

Chronic hepatitis caused by viruses, most commonly hepatitis viruses B and C. [from NCI]

Professional guidelines

PubMed

Treatment and prevention of viral hepatitis in pregnancy.
Dionne-Odom J, Cozzi GD, Franco RA, Njei B, Tita ATN
Am J Obstet Gynecol 2022 Mar;226(3):335-346. Epub 2021 Sep 10 doi: 10.1016/j.ajog.2021.09.002. PMID: 34516961Free PMC Article
Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease.
Urban S, Neumann-Haefelin C, Lampertico P
Gut 2021 Sep;70(9):1782-1794. Epub 2021 Jun 8 doi: 10.1136/gutjnl-2020-323888. PMID: 34103404Free PMC Article
Viral Hepatitis: Etiology, Epidemiology, Transmission, Diagnostics, Treatment, and Prevention.
Lanini S, Ustianowski A, Pisapia R, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):1045-1062. doi: 10.1016/j.idc.2019.08.004. PMID: 31668190

Recent clinical studies

Etiology

Hepatocellular Carcinoma in Chronic Viral Hepatitis: Where Do We Stand?
Russo FP, Zanetto A, Pinto E, Battistella S, Penzo B, Burra P, Farinati F
Int J Mol Sci 2022 Jan 2;23(1) doi: 10.3390/ijms23010500. PMID: 35008926Free PMC Article
Chronic Viral Hepatitis and Metabolic Syndrome/Cardiovascular Risk.
Jarcuska P, Abdel-Razik A, Flisiak R, Singh RB
Can J Gastroenterol Hepatol 2018;2018:7369314. Epub 2018 Nov 4 doi: 10.1155/2018/7369314. PMID: 30519548Free PMC Article
Hepatitis A and B Infections.
Thuener J
Prim Care 2017 Dec;44(4):621-629. Epub 2017 Oct 5 doi: 10.1016/j.pop.2017.07.005. PMID: 29132524
Viral hepatitis and liver cancer.
Ringelhan M, McKeating JA, Protzer U
Philos Trans R Soc Lond B Biol Sci 2017 Oct 19;372(1732) doi: 10.1098/rstb.2016.0274. PMID: 28893941Free PMC Article
HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B.
Nassal M
Gut 2015 Dec;64(12):1972-84. Epub 2015 Jun 5 doi: 10.1136/gutjnl-2015-309809. PMID: 26048673

Diagnosis

Staging Fibrosis in Chronic Viral Hepatitis.
Cardoso AC, Figueiredo-Mendes C, Villela-Nogueira CA, Marcellin P
Viruses 2022 Mar 23;14(4) doi: 10.3390/v14040660. PMID: 35458391Free PMC Article
Current status of hepatitis delta.
Papatheodoridi M, Papatheodoridis GV
Curr Opin Pharmacol 2021 Jun;58:62-67. Epub 2021 Apr 22 doi: 10.1016/j.coph.2021.03.008. PMID: 33895531
Hepatitis B and C.
Mysore KR, Leung DH
Clin Liver Dis 2018 Nov;22(4):703-722. Epub 2018 Aug 22 doi: 10.1016/j.cld.2018.06.002. PMID: 30266158
Hepatitis B and C.
Karnsakul W, Schwarz KB
Pediatr Clin North Am 2017 Jun;64(3):641-658. doi: 10.1016/j.pcl.2017.01.007. PMID: 28502443Free PMC Article
Acute-on-chronic liver failure: an update.
Hernaez R, Solà E, Moreau R, Ginès P
Gut 2017 Mar;66(3):541-553. Epub 2017 Jan 4 doi: 10.1136/gutjnl-2016-312670. PMID: 28053053Free PMC Article

Therapy

Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis.
Cui A, Li B, Wallace MS, Gonye ALK, Oetheimer C, Patel H, Tonnerre P, Holmes JA, Lieb D, Yao BS, Ma A, Roberts K, Damasio M, Chen JH, Piou D, Carlton-Smith C, Brown J, Mylvaganam R, Hon Fung JM, Sade-Feldman M, Aneja J, Gustafson J, Epstein ET, Salloum S, Brisac C, Thabet A, Kim AY, Lauer GM, Hacohen N, Chung RT, Alatrakchi N
J Hepatol 2024 Feb;80(2):251-267. Epub 2023 Mar 25 doi: 10.1016/j.jhep.2023.02.040. PMID: 36972796
Viral hepatitis: Past, present, and future.
Odenwald MA, Paul S
World J Gastroenterol 2022 Apr 14;28(14):1405-1429. doi: 10.3748/wjg.v28.i14.1405. PMID: 35582678Free PMC Article
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
Hepatitis B and C.
Karnsakul W, Schwarz KB
Pediatr Clin North Am 2017 Jun;64(3):641-658. doi: 10.1016/j.pcl.2017.01.007. PMID: 28502443Free PMC Article
Milk thistle in liver diseases: past, present, future.
Abenavoli L, Capasso R, Milic N, Capasso F
Phytother Res 2010 Oct;24(10):1423-32. doi: 10.1002/ptr.3207. PMID: 20564545

Prognosis

Novel function of MOTS-c in mitochondrial remodelling contributes to its antiviral role during HBV infection.
Lin C, Luo L, Xun Z, Zhu C, Huang Y, Ye Y, Zhang J, Chen T, Wu S, Zhan F, Yang B, Liu C, Ran N, Ou Q
Gut 2024 Jan 5;73(2):338-349. doi: 10.1136/gutjnl-2023-330389. PMID: 37788894
Hepatocellular Carcinoma in Chronic Viral Hepatitis: Where Do We Stand?
Russo FP, Zanetto A, Pinto E, Battistella S, Penzo B, Burra P, Farinati F
Int J Mol Sci 2022 Jan 2;23(1) doi: 10.3390/ijms23010500. PMID: 35008926Free PMC Article
Viral hepatitis and pregnancy.
Terrault NA, Levy MT, Cheung KW, Jourdain G
Nat Rev Gastroenterol Hepatol 2021 Feb;18(2):117-130. Epub 2020 Oct 12 doi: 10.1038/s41575-020-00361-w. PMID: 33046891
Predicting Survival After Hepatocellular Carcinoma Resection Using Deep Learning on Histological Slides.
Saillard C, Schmauch B, Laifa O, Moarii M, Toldo S, Zaslavskiy M, Pronier E, Laurent A, Amaddeo G, Regnault H, Sommacale D, Ziol M, Pawlotsky JM, Mulé S, Luciani A, Wainrib G, Clozel T, Courtiol P, Calderaro J
Hepatology 2020 Dec;72(6):2000-2013. doi: 10.1002/hep.31207. PMID: 32108950
Acute-on-chronic liver failure: an update.
Hernaez R, Solà E, Moreau R, Ginès P
Gut 2017 Mar;66(3):541-553. Epub 2017 Jan 4 doi: 10.1136/gutjnl-2016-312670. PMID: 28053053Free PMC Article

Clinical prediction guides

Novel function of MOTS-c in mitochondrial remodelling contributes to its antiviral role during HBV infection.
Lin C, Luo L, Xun Z, Zhu C, Huang Y, Ye Y, Zhang J, Chen T, Wu S, Zhan F, Yang B, Liu C, Ran N, Ou Q
Gut 2024 Jan 5;73(2):338-349. doi: 10.1136/gutjnl-2023-330389. PMID: 37788894
T and NK Cell-Based Immunotherapy in Chronic Viral Hepatitis and Hepatocellular Carcinoma.
Fisicaro P, Boni C
Cells 2022 Jan 6;11(2) doi: 10.3390/cells11020180. PMID: 35053296Free PMC Article
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
Predicting Survival After Hepatocellular Carcinoma Resection Using Deep Learning on Histological Slides.
Saillard C, Schmauch B, Laifa O, Moarii M, Toldo S, Zaslavskiy M, Pronier E, Laurent A, Amaddeo G, Regnault H, Sommacale D, Ziol M, Pawlotsky JM, Mulé S, Luciani A, Wainrib G, Clozel T, Courtiol P, Calderaro J
Hepatology 2020 Dec;72(6):2000-2013. doi: 10.1002/hep.31207. PMID: 32108950
Acute-on-chronic liver failure: an update.
Hernaez R, Solà E, Moreau R, Ginès P
Gut 2017 Mar;66(3):541-553. Epub 2017 Jan 4 doi: 10.1136/gutjnl-2016-312670. PMID: 28053053Free PMC Article

Recent systematic reviews

Chronic Viral Hepatitis Is Associated with Colorectal Neoplasia: A Systematic Review and Meta-Analysis.
Hong SW, Choi WM, Hwang HW, Kim DS, Yoon J, Lee JW, Shim JH, Yang DH, Myung SJ, Yang SK, Byeon JS
Dig Dis Sci 2021 Nov;66(11):3715-3724. Epub 2021 Jan 12 doi: 10.1007/s10620-020-06745-x. PMID: 33433792
eHealth Technologies for Screening, Diagnosis, and Management of Viral Hepatitis: A Systematic Review.
Haridy J, Iyngkaran G, Nicoll A, Hebbard G, Tse E, Fazio T
Clin Gastroenterol Hepatol 2021 Jun;19(6):1139-1150.e30. Epub 2020 Sep 5 doi: 10.1016/j.cgh.2020.09.011. PMID: 32896632
Chronic hepatitis D and hepatocellular carcinoma: A systematic review and meta-analysis of observational studies.
Alfaiate D, Clément S, Gomes D, Goossens N, Negro F
J Hepatol 2020 Sep;73(3):533-539. Epub 2020 Mar 6 doi: 10.1016/j.jhep.2020.02.030. PMID: 32151618
Systematic review: chronic viral hepatitis and metabolic derangement.
Wang CC, Cheng PN, Kao JH
Aliment Pharmacol Ther 2020 Jan;51(2):216-230. Epub 2019 Nov 20 doi: 10.1111/apt.15575. PMID: 31746482
Erectile dysfunction in patients with chronic viral hepatitis: a systematic review of the literature.
Fusco F, D'Anzeo G, Rossi A, Sciorio C, Buonomo AR, d'Emmanuele di Villa Bianca R, Borgia G, Mirone V, Gentile I
Expert Opin Pharmacother 2013 Dec;14(18):2533-44. Epub 2013 Nov 12 doi: 10.1517/14656566.2013.850073. PMID: 24215104

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...