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Small cell osteogenic sarcoma

MedGen UID:
83532
•Concept ID:
C0279622
•
Neoplastic Process
Synonyms: Round cell osteosarcoma; round cell osteosarcoma; SCOS; Small Cell Osteogenic Sarcoma; small cell osteogenic sarcoma; Small cell osteosarcoma; Small Cell Osteosarcoma; small cell osteosarcoma
SNOMED CT: Round cell osteosarcoma (12302002); Small cell osteosarcoma (12302002)
 
Monarch Initiative: MONDO:0002630

Definition

An osteosarcoma usually arising from the metaphysis of long bones. It is characterized by the presence of small cells and osteoid production. The prognosis is usually unfavorable. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall cell osteogenic sarcoma

Professional guidelines

PubMed

Regulation of Molecular Targets in Osteosarcoma Treatment.
Celik B, Cicek K, Leal AF, Tomatsu S
Int J Mol Sci 2022 Oct 20;23(20) doi: 10.3390/ijms232012583. PMID: 36293439Free PMC Article
Ossifying fibromyxoid tumor: morphology, genetics, and differential diagnosis.
Schneider N, Fisher C, Thway K
Ann Diagn Pathol 2016 Feb;20:52-8. Epub 2015 Dec 2 doi: 10.1016/j.anndiagpath.2015.11.002. PMID: 26732302
Diagnosis and treatment of Ewing's sarcoma.
Iwamoto Y
Jpn J Clin Oncol 2007 Feb;37(2):79-89. Epub 2007 Feb 1 doi: 10.1093/jjco/hyl142. PMID: 17272319

Recent clinical studies

Diagnosis

Small cell osteogenic sarcoma of the ribs: cytological, immunohistochemical, and ultrastructural study with literature review.
Park SH, Kim I
Ultrastruct Pathol 1999 Mar-Apr;23(2):133-40. doi: 10.1080/019131299281770. PMID: 10369106
FNA biopsy of small round cell tumors of childhood: cytomorphologic features and the role of ancillary studies.
Silverman JF, Joshi VV
Diagn Cytopathol 1994;10(3):245-55. doi: 10.1002/dc.2840100312. PMID: 8050333
Cytogenetic and pathologic aspects of Ewing's sarcoma and neuroectodermal tumors.
Stephenson CF, Bridge JA, Sandberg AA
Hum Pathol 1992 Nov;23(11):1270-7. doi: 10.1016/0046-8177(92)90295-e. PMID: 1330877

Prognosis

FNA biopsy of small round cell tumors of childhood: cytomorphologic features and the role of ancillary studies.
Silverman JF, Joshi VV
Diagn Cytopathol 1994;10(3):245-55. doi: 10.1002/dc.2840100312. PMID: 8050333
Cytogenetic and pathologic aspects of Ewing's sarcoma and neuroectodermal tumors.
Stephenson CF, Bridge JA, Sandberg AA
Hum Pathol 1992 Nov;23(11):1270-7. doi: 10.1016/0046-8177(92)90295-e. PMID: 1330877

Clinical prediction guides

FNA biopsy of small round cell tumors of childhood: cytomorphologic features and the role of ancillary studies.
Silverman JF, Joshi VV
Diagn Cytopathol 1994;10(3):245-55. doi: 10.1002/dc.2840100312. PMID: 8050333

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