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Benign neoplasm of nasal cavity

MedGen UID:
83859
•Concept ID:
C0347215
•
Neoplastic Process
Synonyms: Benign Nasal Cavity Neoplasm; benign nasal cavity neoplasm; Benign Nasal Cavity Tumor; benign nasal cavity tumor; benign nasal cavity tumour; Benign Neoplasm of Nasal Cavity; benign neoplasm of nasal cavity; Benign Neoplasm of the Nasal Cavity; benign neoplasm of the nasal cavity; Benign tumor of nasal cavity; Benign Tumor of Nasal Cavity; benign tumor of nasal cavity; Benign Tumor of the Nasal Cavity; benign tumor of the nasal cavity; benign tumour of nasal cavity; benign tumour of the nasal cavity; nasal cavity benign neoplasm
SNOMED CT: Benign tumor of nasal cavity (92241005); Benign neoplasm of nasal cavity (92241005)
 
Monarch Initiative: MONDO:0021475

Definition

A neoplasm that arises from the nasal cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include Schneiderian papilloma and salivary gland-type adenoma. [from NCI]

Professional guidelines

PubMed

The contemporary management of cancers of the sinonasal tract in adults.
Thawani R, Kim MS, Arastu A, Feng Z, West MT, Taflin NF, Thein KZ, Li R, Geltzeiler M, Lee N, Fuller CD, Grandis JR, Floudas CS, Heinrich MC, Hanna E, Chandra RA
CA Cancer J Clin 2023 Jan;73(1):72-112. Epub 2022 Aug 2 doi: 10.3322/caac.21752. PMID: 35916666Free PMC Article
Current opinions on diagnosis and treatment of adenoid cystic carcinoma.
Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update.
Biau J, Lapeyre M, Troussier I, Budach W, Giralt J, Grau C, Kazmierska J, Langendijk JA, Ozsahin M, O'Sullivan B, Bourhis J, Grégoire V
Radiother Oncol 2019 May;134:1-9. Epub 2019 Jan 30 doi: 10.1016/j.radonc.2019.01.018. PMID: 31005201

Recent clinical studies

Etiology

Update on olfactory neuroblastoma.
Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A
Virchows Arch 2024 Apr;484(4):567-585. Epub 2024 Feb 22 doi: 10.1007/s00428-024-03758-z. PMID: 38386106
Histopathologic features of nasal glial heterotopia (nasal glioma).
Gilani A, Kleinschmidt-DeMasters BK
Childs Nerv Syst 2022 Jan;38(1):63-75. Epub 2021 Sep 25 doi: 10.1007/s00381-021-05369-4. PMID: 34562130
Introduction.
Bishop JA
Semin Diagn Pathol 2016 Mar;33(2):61. Epub 2015 Dec 29 doi: 10.1053/j.semdp.2015.12.002. PMID: 26754864
Infrasellar craniopharyngioma.
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920
Esthesioneuroblastoma.
Elkon D, Hightower SI, Lim ML, Cantrell RW, Constable WC
Cancer 1979 Sep;44(3):1087-94. doi: 10.1002/1097-0142(197909)44:3<1087::aid-cncr2820440343>3.0.co;2-a. PMID: 383268

Diagnosis

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Nasal Cavity, Paranasal Sinuses and Skull Base.
Thompson LDR, Bishop JA
Head Neck Pathol 2022 Mar;16(1):1-18. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01406-5. PMID: 35312976Free PMC Article
Leiomyosarcoma of the Nasal Cavity.
Saadoun R, Obermueller T, Franke M, Schell A, Mückner K, Riemann R
Ear Nose Throat J 2022 Jun;101(5):NP218-NP221. Epub 2020 Sep 21 doi: 10.1177/0145561320961204. PMID: 32951455
Olfactory Neuroblastoma.
Veyrat M, Vérillaud B, Fiaux-Camous D, Froelich S, Bresson D, Nicolai P, Herman P
Adv Otorhinolaryngol 2020;84:154-167. Epub 2020 Jul 30 doi: 10.1159/000457935. PMID: 32731231
Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options.
Fiani B, Quadri SA, Cathel A, Farooqui M, Ramachandran A, Siddiqi I, Ghanchi H, Zafar A, Berman BW, Siddiqi J
World Neurosurg 2019 Jun;126:194-211. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.03.014. PMID: 30862589
Sinonasal angioleiomyoma.
Lau YW, Vikneswaran T, Tan TY, Tang IP
Med J Malaysia 2016 Jun;71(3):154-5. PMID: 27495895

Therapy

Pediatric pituitary adenomas.
Walz PC, Drapeau A, Shaikhouni A, Eide J, Rugino AJ, Mohyeldin A, Carrau R, Prevedello D
Childs Nerv Syst 2019 Nov;35(11):2107-2118. Epub 2019 Jul 13 doi: 10.1007/s00381-019-04293-y. PMID: 31302729
Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options.
Fiani B, Quadri SA, Cathel A, Farooqui M, Ramachandran A, Siddiqi I, Ghanchi H, Zafar A, Berman BW, Siddiqi J
World Neurosurg 2019 Jun;126:194-211. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.03.014. PMID: 30862589
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article
Esthesioneuroblastoma.
Klepin HD, McMullen KP, Lesser GJ
Curr Treat Options Oncol 2005 Nov;6(6):509-18. doi: 10.1007/s11864-005-0029-7. PMID: 16242055
Malignant craniopharyngioma.
Kristopaitis T, Thomas C, Petruzzelli GJ, Lee JM
Arch Pathol Lab Med 2000 Sep;124(9):1356-60. doi: 10.5858/2000-124-1356-MC. PMID: 10975938

Prognosis

Olfactory Neuroblastoma.
Veyrat M, Vérillaud B, Fiaux-Camous D, Froelich S, Bresson D, Nicolai P, Herman P
Adv Otorhinolaryngol 2020;84:154-167. Epub 2020 Jul 30 doi: 10.1159/000457935. PMID: 32731231
Sinonasal angioleiomyoma.
Lau YW, Vikneswaran T, Tan TY, Tang IP
Med J Malaysia 2016 Jun;71(3):154-5. PMID: 27495895
Introduction.
Bishop JA
Semin Diagn Pathol 2016 Mar;33(2):61. Epub 2015 Dec 29 doi: 10.1053/j.semdp.2015.12.002. PMID: 26754864
Of mice and men: olfactory neuroblastoma among animals and humans.
Lubojemska A, Borejko M, Czapiewski P, Dziadziuszko R, Biernat W
Vet Comp Oncol 2016 Sep;14(3):e70-82. Epub 2014 Jul 12 doi: 10.1111/vco.12102. PMID: 25041470
Infrasellar craniopharyngioma.
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920

Clinical prediction guides

Update on olfactory neuroblastoma.
Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A
Virchows Arch 2024 Apr;484(4):567-585. Epub 2024 Feb 22 doi: 10.1007/s00428-024-03758-z. PMID: 38386106
Histopathologic features of nasal glial heterotopia (nasal glioma).
Gilani A, Kleinschmidt-DeMasters BK
Childs Nerv Syst 2022 Jan;38(1):63-75. Epub 2021 Sep 25 doi: 10.1007/s00381-021-05369-4. PMID: 34562130
Of mice and men: olfactory neuroblastoma among animals and humans.
Lubojemska A, Borejko M, Czapiewski P, Dziadziuszko R, Biernat W
Vet Comp Oncol 2016 Sep;14(3):e70-82. Epub 2014 Jul 12 doi: 10.1111/vco.12102. PMID: 25041470
Infrasellar craniopharyngioma.
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920
Nasal angiomyolipoma.
Erkiliç S, Koçer NE, Mumbuç S, Kanlikama M
Acta Otolaryngol 2005 Apr;125(4):446-8. doi: 10.1080/00016480510029419. PMID: 15823821

Recent systematic reviews

Overall and disease-specific survival of sinonasal adenoid cystic carcinoma: a systematic review and meta-analysis.
Mauthe T, Holzmann D, Soyka MB, Mueller SA, Balermpas P, Held U, Freiberger SN, Rupp NJ, Meerwein CM
Rhinology 2023 Dec 1;61(6):508-518. doi: 10.4193/Rhin23.204. PMID: 37703531
Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review.
Runge A, Randhawa A, Mayo-Patiño M, Santer M, Hartl R, Dejaco D, Eloy JA
Am J Rhinol Allergy 2023 Sep;37(5):586-592. Epub 2023 Apr 24 doi: 10.1177/19458924231170464. PMID: 37093753
Expert Consensus Statement: Management of Dysphagia in Head and Neck Cancer Patients.
Kuhn MA, Gillespie MB, Ishman SL, Ishii LE, Brody R, Cohen E, Dhar SI, Hutcheson K, Jefferson G, Johnson F, Rameau A, Sher D, Starmer H, Strohl M, Ulmer K, Vaitaitis V, Begum S, Batjargal M, Dhepyasuwan N
Otolaryngol Head Neck Surg 2023 Apr;168(4):571-592. doi: 10.1002/ohn.302. PMID: 36965195
Sino-nasal hemangiopericytoma: a case series and systematic literature review.
Warman M, Syn-Hershko A, Cohen O, Tzipin Y, Lahav Y, Tessler I
Eur Arch Otorhinolaryngol 2022 Aug;279(8):3989-3996. Epub 2022 Feb 1 doi: 10.1007/s00405-021-07239-w. PMID: 35103868
Characteristics and management of sinonasal paragangliomas: a systematic review.
Nguyen BK, Patel NM, Arianpour K, Svider PF, Folbe AJ, Hsueh WD, Eloy JA
Int Forum Allergy Rhinol 2019 Apr;9(4):413-426. Epub 2018 Dec 20 doi: 10.1002/alr.22261. PMID: 30570216

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