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Recurrent Childhood Non-Hodgkin Lymphoma

MedGen UID:: 857343
•Concept ID:: C3897749
•: Neoplastic Process

Definition

The reemergence of non-Hodgkin lymphoma in childhood after a period of remission. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRecurrent Childhood Non-Hodgkin Lymphoma

Hematopoietic and Lymphoid System Disorder
- Hematologic disorder
  - Hematologic neoplasm
    - Lymphoma
      - Non-Hodgkin lymphoma
        Childhood Non-Hodgkin Lymphoma
        Recurrent Childhood Non-Hodgkin Lymphoma
        Recurrent Childhood Anaplastic Large Cell Lymphoma
        Recurrent Childhood Burkitt Lymphoma
        Recurrent Childhood Grade III Lymphomatoid Granulomatosis
        Recurrent Childhood Lymphoblastic Lymphoma

Professional guidelines

PubMed

Pharmacotherapeutic Management of Pediatric Lymphoma.

Mauz-Körholz C, Ströter N, Baumann J, Botzen A, Körholz K, Körholz D
Paediatr Drugs 2018 Feb;20(1):43-57. doi: 10.1007/s40272-017-0265-x. PMID: 29127674

Treatment of pediatric lymphoma in Japan: Current status and plans for the future.

Kobayashi R, Sunami S, Mitsui T, Nakazawa A, Koga Y, Mori T, Tanaka F, Ueyama J, Osumi T, Fukano R, Ohki K, Sekimizu M, Mori T; Lymphoma Committee; Japanese Pediatric Leukemia/Lymphoma Study Group
Pediatr Int 2015 Aug;57(4):523-34. doi: 10.1111/ped.12725. PMID: 26096060

Management of pediatric non-Hodgkin's lymphoma.

Blay JY, Louis D, Bouffet E, Thiesse P, Biron P, Favrot MC, Brunat-Mentigny M, Philip T
Blood Rev 1991 Jun;5(2):90-7. doi: 10.1016/0268-960x(91)90040-j. PMID: 1912759

See all (23)

Recent clinical studies

Etiology

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.

Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573 Free PMC Article

The epidemiology of osteosarcoma.

Ottaviani G, Jaffe N
Cancer Treat Res 2009;152:3-13. doi: 10.1007/978-1-4419-0284-9_1. PMID: 20213383

Infective dermatitis.

Trope BM, Lenzi ME
Clin Dermatol 2009 May-Jun;27(3):281-4. doi: 10.1016/j.clindermatol.2008.10.007. PMID: 19362690

Chlorambucil-induced seizures.

Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

Lymphoblastic leukaemia and non-Hodgkin's lymphoma.

Lilleyman JS, Pinkerton CR
Br Med Bull 1996 Oct;52(4):742-63. doi: 10.1093/oxfordjournals.bmb.a011580. PMID: 9039729

See all (140)

Diagnosis

Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities.

Burkhardt B, Hermiston ML
Br J Haematol 2019 Jun;185(6):1158-1170. Epub 2019 Feb 27 doi: 10.1111/bjh.15793. PMID: 30809797

Adult-Onset Atopic Dermatitis.

Silverberg JI
J Allergy Clin Immunol Pract 2019 Jan;7(1):28-33. doi: 10.1016/j.jaip.2018.09.029. PMID: 30598180

Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma.

Miles RR, Shah RK, Frazer JK
Br J Haematol 2016 May;173(4):582-96. Epub 2016 Mar 11 doi: 10.1111/bjh.14011. PMID: 26969846 Free PMC Article

Infective dermatitis.

Trope BM, Lenzi ME
Clin Dermatol 2009 May-Jun;27(3):281-4. doi: 10.1016/j.clindermatol.2008.10.007. PMID: 19362690

Chlorambucil-induced seizures.

Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

See all (144)

Therapy

Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR).

Whitlock JA, Malvar J, Dalla-Pozza L, Goldberg JM, Silverman LB, Ziegler DS, Attarbaschi A, Brown PA, Gardner RA, Gaynon PS, Hutchinson R, Huynh VT, Jeha S, Marcus L, Messinger Y, Schultz KR, Cassar J, Locatelli F, Zwaan CM, Wood BL, Sposto R, Gore L
Pediatr Blood Cancer 2022 Nov;69(11):e29901. Epub 2022 Aug 21 doi: 10.1002/pbc.29901. PMID: 35989458

Bispecific anti-CD20, anti-CD19 CAR T cells for relapsed B cell malignancies: a phase 1 dose escalation and expansion trial.

Shah NN, Johnson BD, Schneider D, Zhu F, Szabo A, Keever-Taylor CA, Krueger W, Worden AA, Kadan MJ, Yim S, Cunningham A, Hamadani M, Fenske TS, Dropulić B, Orentas R, Hari P
Nat Med 2020 Oct;26(10):1569-1575. Epub 2020 Oct 5 doi: 10.1038/s41591-020-1081-3. PMID: 33020647

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.

Pharmacotherapeutic Management of Pediatric Lymphoma.

Mauz-Körholz C, Ströter N, Baumann J, Botzen A, Körholz K, Körholz D
Paediatr Drugs 2018 Feb;20(1):43-57. doi: 10.1007/s40272-017-0265-x. PMID: 29127674

Chlorambucil-induced seizures.

Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

See all (123)

Prognosis

Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR).

Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities.

Burkhardt B, Hermiston ML
Br J Haematol 2019 Jun;185(6):1158-1170. Epub 2019 Feb 27 doi: 10.1111/bjh.15793. PMID: 30809797

Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma.

Miles RR, Shah RK, Frazer JK
Br J Haematol 2016 May;173(4):582-96. Epub 2016 Mar 11 doi: 10.1111/bjh.14011. PMID: 26969846 Free PMC Article

The epidemiology of osteosarcoma.

Ottaviani G, Jaffe N
Cancer Treat Res 2009;152:3-13. doi: 10.1007/978-1-4419-0284-9_1. PMID: 20213383

Lymphoblastic leukaemia and non-Hodgkin's lymphoma.

Lilleyman JS, Pinkerton CR
Br Med Bull 1996 Oct;52(4):742-63. doi: 10.1093/oxfordjournals.bmb.a011580. PMID: 9039729

See all (134)

Clinical prediction guides

Outcome and prognostic factors in childhood B non-Hodgkin lymphoma from India: Report by the Indian Pediatric Oncology Group (InPOG-NHL-16-01 study).

Rahiman EA, Bakhshi S, Deepam Pushpam, Ramamoorthy J, Das A, Ghara N, Kalra M, Kapoor G, Meena JP, Siddaigarhi S, Thulkar S, Sharma MC, Srinivasan R, Trehan A
Pediatr Hematol Oncol 2022 Aug;39(5):391-405. Epub 2022 Jan 3 doi: 10.1080/08880018.2021.2002485. PMID: 34978257

Analysis of clinicopathological and cytogenetic differences between B-lymphoblastic lymphoma and B-lymphoblastic leukemia in childhood.

Knez V, Bao L, Carstens B, Liang X
Leuk Lymphoma 2020 Sep;61(9):2129-2135. Epub 2020 May 19 doi: 10.1080/10428194.2020.1761970. PMID: 32427530

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.

Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma.

Miles RR, Shah RK, Frazer JK
Br J Haematol 2016 May;173(4):582-96. Epub 2016 Mar 11 doi: 10.1111/bjh.14011. PMID: 26969846 Free PMC Article

Chlorambucil-induced seizures.

Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

See all (56)