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Intracranial Hemorrhage Related to Birth

MedGen UID:
858300
•Concept ID:
C3898706
•
Finding

Definition

Bleeding within the skull of a newborn infant occurring during labor and/or delivery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial Hemorrhage Related to Birth

Professional guidelines

PubMed

Aneurysmal subarachnoid hemorrhage in pregnancy: National trends of treatment, predictors, and outcomes.
Khatibi K, Saber H, Patel S, Mejia LLP, Kaneko N, Szeder V, Nour M, Jahan R, Tateshima S, Colby G, Duckwiler G, Afshar Y
PLoS One 2023;18(5):e0285082. Epub 2023 May 4 doi: 10.1371/journal.pone.0285082. PMID: 37141265Free PMC Article
The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: Management of infants and neonates with tetralogy of Fallot.
Expert Consensus Panel:, Miller JR, Stephens EH, Goldstone AB, Glatz AC, Kane L, Van Arsdell GS, Stellin G, Barron DJ, d'Udekem Y, Benson L, Quintessenza J, Ohye RG, Talwar S, Fremes SE, Emani SM, Eghtesady P
J Thorac Cardiovasc Surg 2023 Jan;165(1):221-250. Epub 2022 Oct 26 doi: 10.1016/j.jtcvs.2022.07.025. PMID: 36522807
Consensus statement on abusive head trauma in infants and young children.
Choudhary AK, Servaes S, Slovis TL, Palusci VJ, Hedlund GL, Narang SK, Moreno JA, Dias MS, Christian CW, Nelson MD Jr, Silvera VM, Palasis S, Raissaki M, Rossi A, Offiah AC
Pediatr Radiol 2018 Aug;48(8):1048-1065. Epub 2018 May 23 doi: 10.1007/s00247-018-4149-1. PMID: 29796797

Recent clinical studies

Etiology

Emicizumab prophylaxis in infants with hemophilia A (HAVEN 7): primary analysis of a phase 3b open-label trial.
Pipe SW, Collins P, Dhalluin C, Kenet G, Schmitt C, Buri M, Jiménez-Yuste V, Peyvandi F, Young G, Oldenburg J, Mancuso ME, Kavakli K, Kiialainen A, Deb S, Niggli M, Chang T, Lehle M, Fijnvandraat K
Blood 2024 Apr 4;143(14):1355-1364. doi: 10.1182/blood.2023021832. PMID: 38127586Free PMC Article
The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: Management of infants and neonates with tetralogy of Fallot.
Expert Consensus Panel:, Miller JR, Stephens EH, Goldstone AB, Glatz AC, Kane L, Van Arsdell GS, Stellin G, Barron DJ, d'Udekem Y, Benson L, Quintessenza J, Ohye RG, Talwar S, Fremes SE, Emani SM, Eghtesady P
J Thorac Cardiovasc Surg 2023 Jan;165(1):221-250. Epub 2022 Oct 26 doi: 10.1016/j.jtcvs.2022.07.025. PMID: 36522807
Birth-related subdural hemorrhage: prevalence and imaging morphology.
Nikam RM, Kandula VV, Yue X, Krishnan V, Kumbhar SS, Averill LW, Paudyal B, Choudhary AK
Pediatr Radiol 2021 May;51(6):939-946. Epub 2021 Apr 8 doi: 10.1007/s00247-021-05060-5. PMID: 33830289
The Impact of Prematurity on Social and Emotional Development.
Leon Hernandez A
Clin Perinatol 2018 Sep;45(3):547-555. Epub 2018 Jul 2 doi: 10.1016/j.clp.2018.05.010. PMID: 30144854
Neonatal alloimmune thrombocytopenic purpura.
Deaver JE, Leppert PC, Zaroulis CG
Am J Perinatol 1986 Apr;3(2):127-31. doi: 10.1055/s-2007-999848. PMID: 3516167

Diagnosis

Birth-related subdural hemorrhage: prevalence and imaging morphology.
Nikam RM, Kandula VV, Yue X, Krishnan V, Kumbhar SS, Averill LW, Paudyal B, Choudhary AK
Pediatr Radiol 2021 May;51(6):939-946. Epub 2021 Apr 8 doi: 10.1007/s00247-021-05060-5. PMID: 33830289
The Impact of Prematurity on Social and Emotional Development.
Leon Hernandez A
Clin Perinatol 2018 Sep;45(3):547-555. Epub 2018 Jul 2 doi: 10.1016/j.clp.2018.05.010. PMID: 30144854
Consensus statement on abusive head trauma in infants and young children.
Choudhary AK, Servaes S, Slovis TL, Palusci VJ, Hedlund GL, Narang SK, Moreno JA, Dias MS, Christian CW, Nelson MD Jr, Silvera VM, Palasis S, Raissaki M, Rossi A, Offiah AC
Pediatr Radiol 2018 Aug;48(8):1048-1065. Epub 2018 May 23 doi: 10.1007/s00247-018-4149-1. PMID: 29796797
Circulatory Management Focusing on Preventing Intraventricular Hemorrhage and Pulmonary Hemorrhage in Preterm Infants.
Su BH, Lin HY, Huang FK, Tsai ML, Huang YT
Pediatr Neonatol 2016 Dec;57(6):453-462. Epub 2016 Feb 4 doi: 10.1016/j.pedneo.2016.01.001. PMID: 26993561
Neonatal alloimmune thrombocytopenic purpura.
Deaver JE, Leppert PC, Zaroulis CG
Am J Perinatol 1986 Apr;3(2):127-31. doi: 10.1055/s-2007-999848. PMID: 3516167

Therapy

Emicizumab prophylaxis in infants with hemophilia A (HAVEN 7): primary analysis of a phase 3b open-label trial.
Pipe SW, Collins P, Dhalluin C, Kenet G, Schmitt C, Buri M, Jiménez-Yuste V, Peyvandi F, Young G, Oldenburg J, Mancuso ME, Kavakli K, Kiialainen A, Deb S, Niggli M, Chang T, Lehle M, Fijnvandraat K
Blood 2024 Apr 4;143(14):1355-1364. doi: 10.1182/blood.2023021832. PMID: 38127586Free PMC Article
The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: Management of infants and neonates with tetralogy of Fallot.
Expert Consensus Panel:, Miller JR, Stephens EH, Goldstone AB, Glatz AC, Kane L, Van Arsdell GS, Stellin G, Barron DJ, d'Udekem Y, Benson L, Quintessenza J, Ohye RG, Talwar S, Fremes SE, Emani SM, Eghtesady P
J Thorac Cardiovasc Surg 2023 Jan;165(1):221-250. Epub 2022 Oct 26 doi: 10.1016/j.jtcvs.2022.07.025. PMID: 36522807
Splenic rupture and intracranial haemorrhage in a haemophilic neonate: case report and literature review.
Adamu I, Asarian A, Xiao P
Afr J Paediatr Surg 2012 May-Aug;9(2):163-5. doi: 10.4103/0189-6725.99408. PMID: 22878771
Surfactant therapy and intracranial hemorrhage: review of the literature and results of new analyses.
Gunkel JH, Banks PL
Pediatrics 1993 Dec;92(6):775-86. PMID: 8233736
Neonatal alloimmune thrombocytopenic purpura.
Deaver JE, Leppert PC, Zaroulis CG
Am J Perinatol 1986 Apr;3(2):127-31. doi: 10.1055/s-2007-999848. PMID: 3516167

Prognosis

Aneurysmal subarachnoid hemorrhage in pregnancy: National trends of treatment, predictors, and outcomes.
Khatibi K, Saber H, Patel S, Mejia LLP, Kaneko N, Szeder V, Nour M, Jahan R, Tateshima S, Colby G, Duckwiler G, Afshar Y
PLoS One 2023;18(5):e0285082. Epub 2023 May 4 doi: 10.1371/journal.pone.0285082. PMID: 37141265Free PMC Article
Incidence and Time Trends of Pregnancy-Related Stroke Between 2010 and 2018: The Nationwide CONCEPTION Study.
Martin A, Lailler G, Béjot Y, Gabet A, Grave C, Regnault N, Chatignoux E, Moutengou E, Deneux-Tharaux C, Kretz S, Mounier-Vehier C, Tsatsaris V, Plu-Bureau G, Blacher J, Olié V
Neurology 2022 Oct 11;99(15):e1598-e1608. Epub 2022 Aug 29 doi: 10.1212/WNL.0000000000200944. PMID: 36038274Free PMC Article
Incidence and mortality rates of intracranial hemorrhage in hemophilia: a systematic review and meta-analysis.
Zwagemaker AF, Gouw SC, Jansen JS, Vuong C, Coppens M, Hu Q, Feng X, Kim SK, Van der Bom JG, Fijnvandraat K
Blood 2021 Dec 30;138(26):2853-2873. doi: 10.1182/blood.2021011849. PMID: 34411236
Intracranial hemorrhage in term neonates.
Hong HS, Lee JY
Childs Nerv Syst 2018 Jun;34(6):1135-1143. Epub 2018 Apr 10 doi: 10.1007/s00381-018-3788-8. PMID: 29637304Free PMC Article
Fetal alloimmune thrombocytopenia.
Bussel JB, Zabusky MR, Berkowitz RL, McFarland JG
N Engl J Med 1997 Jul 3;337(1):22-6. doi: 10.1056/NEJM199707033370104. PMID: 9203427

Clinical prediction guides

The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: Management of infants and neonates with tetralogy of Fallot.
Expert Consensus Panel:, Miller JR, Stephens EH, Goldstone AB, Glatz AC, Kane L, Van Arsdell GS, Stellin G, Barron DJ, d'Udekem Y, Benson L, Quintessenza J, Ohye RG, Talwar S, Fremes SE, Emani SM, Eghtesady P
J Thorac Cardiovasc Surg 2023 Jan;165(1):221-250. Epub 2022 Oct 26 doi: 10.1016/j.jtcvs.2022.07.025. PMID: 36522807
Incidence and Time Trends of Pregnancy-Related Stroke Between 2010 and 2018: The Nationwide CONCEPTION Study.
Martin A, Lailler G, Béjot Y, Gabet A, Grave C, Regnault N, Chatignoux E, Moutengou E, Deneux-Tharaux C, Kretz S, Mounier-Vehier C, Tsatsaris V, Plu-Bureau G, Blacher J, Olié V
Neurology 2022 Oct 11;99(15):e1598-e1608. Epub 2022 Aug 29 doi: 10.1212/WNL.0000000000200944. PMID: 36038274Free PMC Article
Birth-related subdural hemorrhage: prevalence and imaging morphology.
Nikam RM, Kandula VV, Yue X, Krishnan V, Kumbhar SS, Averill LW, Paudyal B, Choudhary AK
Pediatr Radiol 2021 May;51(6):939-946. Epub 2021 Apr 8 doi: 10.1007/s00247-021-05060-5. PMID: 33830289
Intracranial hemorrhage in term neonates.
Hong HS, Lee JY
Childs Nerv Syst 2018 Jun;34(6):1135-1143. Epub 2018 Apr 10 doi: 10.1007/s00381-018-3788-8. PMID: 29637304Free PMC Article
Fetal alloimmune thrombocytopenia.
Bussel JB, Zabusky MR, Berkowitz RL, McFarland JG
N Engl J Med 1997 Jul 3;337(1):22-6. doi: 10.1056/NEJM199707033370104. PMID: 9203427

Recent systematic reviews

Premature and Extracorporeal Life Support: Is it Time? A Systematic Review.
Burgos CM, Frenckner B, Broman LM
ASAIO J 2022 May 1;68(5):633-645. Epub 2021 Sep 24 doi: 10.1097/MAT.0000000000001555. PMID: 34593681
Incidence and mortality rates of intracranial hemorrhage in hemophilia: a systematic review and meta-analysis.
Zwagemaker AF, Gouw SC, Jansen JS, Vuong C, Coppens M, Hu Q, Feng X, Kim SK, Van der Bom JG, Fijnvandraat K
Blood 2021 Dec 30;138(26):2853-2873. doi: 10.1182/blood.2021011849. PMID: 34411236
Global incidence of intraventricular hemorrhage among extremely preterm infants: a systematic literature review.
Siffel C, Kistler KD, Sarda SP
J Perinat Med 2021 Nov 25;49(9):1017-1026. Epub 2021 Mar 19 doi: 10.1515/jpm-2020-0331. PMID: 33735943
Effectiveness of prothrombin complex concentrate (PCC) in neonates and infants with bleeding or risk of bleeding: a systematic review and meta-analysis.
Zeng L, Choonara I, Zhang L, Li Y, Shi J
Eur J Pediatr 2017 May;176(5):581-589. Epub 2017 Mar 9 doi: 10.1007/s00431-017-2877-0. PMID: 28281092
Renal dysfunction and thrombolytic therapy in patients with acute ischemic stroke: a systematic review and meta-analysis.
Hao Z, Yang C, Liu M, Wu B
Medicine (Baltimore) 2014 Dec;93(28):e286. doi: 10.1097/MD.0000000000000286. PMID: 25526464Free PMC Article

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