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Abnormal nasal base norphology

MedGen UID:
868324
•Concept ID:
C4022718
•
Anatomical Abnormality
Synonyms: Abnormal nasal base; Abnormality of base of nose; Anomaly of base of nose; Anomaly of nasal base; Deformity of base of nose; Deformity of nasal base; Malformation of base of nose; Malformation of nasal base
 
HPO: HP:0012808

Definition

An anomaly of the nasal base, which can be conceived of as an imaginary line between the most lateral points of the external inferior attachments of the alae nasi to the face. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal nasal base norphology

Professional guidelines

PubMed

Practical multidisciplinary framework for the assessment and management of patients with unexplained chronic aerodigestive symptoms.
Quigley N, Mistry SG, Vasant DH, Vasani S
BMJ Open Gastroenterol 2023 Nov 23;10(1) doi: 10.1136/bmjgast-2022-000883. PMID: 37996120Free PMC Article
Smell and Taste Disorders in Primary Care.
Savard DJ, Ursua FG, Gaddey HL
Am Fam Physician 2023 Sep;108(3):240-248. PMID: 37725455
Best Practices for the Diagnosis and Evaluation of Infants With Robin Sequence: A Clinical Consensus Report.
Breugem CC, Evans KN, Poets CF, Suri S, Picard A, Filip C, Paes EC, Mehendale FV, Saal HM, Basart H, Murthy J, Joosten KF, Speleman L, Collares MV, van den Boogaard MJ, Muradin M, Andersson ME, Kogo M, Farlie PG, Don Griot P, Mossey PA, Slator R, Abadie V, Hong P
JAMA Pediatr 2016 Sep 1;170(9):894-902. doi: 10.1001/jamapediatrics.2016.0796. PMID: 27429161

Recent clinical studies

Etiology

Stability of nasal symmetry following primary cleft lip and nasal repair: five years of follow-up.
Alkebsi K, Sakran KA, Abdo Y, Shi B, Li C
Int J Oral Maxillofac Surg 2023 Apr;52(4):451-459. Epub 2022 Aug 13 doi: 10.1016/j.ijom.2022.07.011. PMID: 35973881
Three-Dimensional Analysis of Definitive Secondary Unilateral Cleft Rhinoplasty Using Cartilage Graft.
Hantawornchaikit T, Arayasantiparb R, Kc K, Boonsiriseth K
Cleft Palate Craniofac J 2022 Aug;59(8):1072-1078. Epub 2021 Aug 17 doi: 10.1177/10556656211034099. PMID: 34402317
Post-viral effects of COVID-19 in the olfactory system and their implications.
Xydakis MS, Albers MW, Holbrook EH, Lyon DM, Shih RY, Frasnelli JA, Pagenstecher A, Kupke A, Enquist LW, Perlman S
Lancet Neurol 2021 Sep;20(9):753-761. Epub 2021 Jul 30 doi: 10.1016/S1474-4422(21)00182-4. PMID: 34339626Free PMC Article
Innovations in Endonasal Sinus Surgery in Children.
Shay SG, Valika T, Chun R, Rastatter J
Otolaryngol Clin North Am 2019 Oct;52(5):875-890. Epub 2019 Jul 26 doi: 10.1016/j.otc.2019.06.003. PMID: 31353137
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416

Diagnosis

Imaging of Developmental Skull Base Abnormalities.
Siddiqui A, Connor SEJ
Neuroimaging Clin N Am 2021 Nov;31(4):621-647. doi: 10.1016/j.nic.2021.06.004. PMID: 34689936
Rhinogenic and sinus headache - Literature review.
Bernichi JV, Rizzo VL, Villa JF, Santos RF, Caparroz FA
Am J Otolaryngol 2021 Nov-Dec;42(6):103113. Epub 2021 Jun 17 doi: 10.1016/j.amjoto.2021.103113. PMID: 34175774
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Raine syndrome: an overview.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B
Eur J Med Genet 2014 Sep;57(9):536-42. Epub 2014 Jul 12 doi: 10.1016/j.ejmg.2014.07.001. PMID: 25019372
Gustatory rhinitis.
Georgalas C, Jovancevic L
Curr Opin Otolaryngol Head Neck Surg 2012 Feb;20(1):9-14. doi: 10.1097/MOO.0b013e32834dfb52. PMID: 22143339

Therapy

Rhinoplasty in Patients with Cleft Lip Nasal Deformity: Correcting the Alar Base.
DeVictor SR, Tollefson TT
Facial Plast Surg 2023 Dec;39(6):668-673. Epub 2023 Jul 11 doi: 10.1055/a-2127-3665. PMID: 37433309
Systematic Surgical Approach to Alar Base Surgery in Rhinoplasty.
Rohrich RJ, Savetsky IL, Suszynski TM, Mohan R, Avashia YJ
Plast Reconstr Surg 2020 Dec;146(6):1259-1267. doi: 10.1097/PRS.0000000000007385. PMID: 33234955
Gustatory rhinitis.
Georgalas C, Jovancevic L
Curr Opin Otolaryngol Head Neck Surg 2012 Feb;20(1):9-14. doi: 10.1097/MOO.0b013e32834dfb52. PMID: 22143339
Alar rim deformities.
Guyuron B
Plast Reconstr Surg 2001 Mar;107(3):856-63. doi: 10.1097/00006534-200103000-00032. PMID: 11304615
Sella-Nasion line revisited.
Sarhan OA
J Oral Rehabil 1995 Dec;22(12):905-8. doi: 10.1111/j.1365-2842.1995.tb00239.x. PMID: 9217302

Prognosis

Stability of nasal symmetry following primary cleft lip and nasal repair: five years of follow-up.
Alkebsi K, Sakran KA, Abdo Y, Shi B, Li C
Int J Oral Maxillofac Surg 2023 Apr;52(4):451-459. Epub 2022 Aug 13 doi: 10.1016/j.ijom.2022.07.011. PMID: 35973881
Post-viral effects of COVID-19 in the olfactory system and their implications.
Xydakis MS, Albers MW, Holbrook EH, Lyon DM, Shih RY, Frasnelli JA, Pagenstecher A, Kupke A, Enquist LW, Perlman S
Lancet Neurol 2021 Sep;20(9):753-761. Epub 2021 Jul 30 doi: 10.1016/S1474-4422(21)00182-4. PMID: 34339626Free PMC Article
Choanal Atresia and Other Neonatal Nasal Anomalies.
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Advanced airway management strategies for severe OSAS and craniofacial anomalies.
Gungor A
Am J Otolaryngol 2017 Jan-Feb;38(1):77-81. Epub 2016 Sep 28 doi: 10.1016/j.amjoto.2016.09.016. PMID: 27756487
Raine syndrome: an overview.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B
Eur J Med Genet 2014 Sep;57(9):536-42. Epub 2014 Jul 12 doi: 10.1016/j.ejmg.2014.07.001. PMID: 25019372

Clinical prediction guides

Lip-Shortening Surgery.
Gatti JE
Plast Reconstr Surg 2023 Oct 1;152(4):765-772. Epub 2023 Mar 7 doi: 10.1097/PRS.0000000000010361. PMID: 36877617
Three-Dimensional Analysis of Definitive Secondary Unilateral Cleft Rhinoplasty Using Cartilage Graft.
Hantawornchaikit T, Arayasantiparb R, Kc K, Boonsiriseth K
Cleft Palate Craniofac J 2022 Aug;59(8):1072-1078. Epub 2021 Aug 17 doi: 10.1177/10556656211034099. PMID: 34402317
Cranial Pair 0: The Nervus Terminalis.
Peña-Melián Á, Cabello-de la Rosa JP, Gallardo-Alcañiz MJ, Vaamonde-Gamo J, Relea-Calatayud F, González-López L, Villanueva-Anguita P, Flores-Cuadrado A, Saiz-Sánchez D, Martínez-Marcos A
Anat Rec (Hoboken) 2019 Mar;302(3):394-404. Epub 2018 May 17 doi: 10.1002/ar.23826. PMID: 29663690
Johanson-Blizzard syndrome.
Almashraki N, Abdulnabee MZ, Sukalo M, Alrajoudi A, Sharafadeen I, Zenker M
World J Gastroenterol 2011 Oct 7;17(37):4247-50. doi: 10.3748/wjg.v17.i37.4247. PMID: 22072859Free PMC Article
Development of the facial midline.
Carstens MH
J Craniofac Surg 2002 Jan;13(1):129-87; discussion 188-90. doi: 10.1097/00001665-200201000-00032. PMID: 11887012

Recent systematic reviews

Systematic Review and Critical Appraisal of the Evidence Base for Nasoalveolar Molding (NAM).
Dunworth K, Porras Fimbres D, Trotta R, Hollins A, Shammas R, Allori AC, Santiago PE
Cleft Palate Craniofac J 2024 Apr;61(4):654-677. Epub 2022 Nov 4 doi: 10.1177/10556656221136325. PMID: 36330703
Empty Nose Syndrome Pathophysiology: A Systematic Review.
Kanjanawasee D, Campbell RG, Rimmer J, Alvarado R, Kanjanaumporn J, Snidvongs K, Kalish L, Harvey RJ, Sacks R
Otolaryngol Head Neck Surg 2022 Sep;167(3):434-451. Epub 2021 Oct 19 doi: 10.1177/01945998211052919. PMID: 34665687
Endonasal Endoscopic Surgery for Pediatric Sellar and Suprasellar Lesions: A Systematic Review and Meta-analysis.
Lee JA, Cooper RL, Nguyen SA, Schlosser RJ, Gudis DA
Otolaryngol Head Neck Surg 2020 Aug;163(2):284-292. Epub 2020 Mar 24 doi: 10.1177/0194599820913637. PMID: 32204653
Pediatric rhinoplasty: A discussion of perioperative considerations and systematic review.
Gupta A, Svider PF, Rayess H, Sheyn A, Folbe AJ, Eloy JA, Zuliani G, Carron MA
Int J Pediatr Otorhinolaryngol 2017 Jan;92:11-16. Epub 2016 Oct 26 doi: 10.1016/j.ijporl.2016.10.027. PMID: 28012510
A systematic review of the oral and craniofacial manifestations of cri du chat syndrome.
Corcuera-Flores JR, Casttellanos-Cosano L, Torres-Lagares D, Serrera-Figallo MÁ, Rodríguez-Caballero Á, Machuca-Portillo G
Clin Anat 2016 Jul;29(5):555-60. Epub 2015 Dec 21 doi: 10.1002/ca.22654. PMID: 26457586

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