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Abnormal occipital bone morphology

MedGen UID:
868565
•Concept ID:
C4022964
•
Anatomical Abnormality
Synonym: Abnormality of the occipital bone
 
HPO: HP:0012294

Definition

Abnormality of the occipital bone of the skull. [from HPO]

Professional guidelines

PubMed

Chiari Malformation (Update on Diagnosis and Treatment).
Rosenblum JS, Pomeraniec IJ, Heiss JD
Neurol Clin 2022 May;40(2):297-307. Epub 2022 Mar 31 doi: 10.1016/j.ncl.2021.11.007. PMID: 35465876Free PMC Article
Treatment of Syndromic Craniosynostosis by Anterior and Posterior Vault Distraction Osteogenesis (A-PVDO).
Shen W, Cui J, Chen J, Yi J, Kong L, Sun B
J Craniofac Surg 2022 Mar-Apr 01;33(2):654-656. doi: 10.1097/SCS.0000000000008289. PMID: 34690305
Craniovertebral junction anomalies: diagnosis and management.
Menezes AH
Semin Pediatr Neurol 1997 Sep;4(3):209-23. doi: 10.1016/s1071-9091(97)80038-1. PMID: 9323790

Recent clinical studies

Etiology

Morphology of the Occipital Bones and Foramen Magnum Resulting From Premature Minor Suture Fusion in Crouzon Syndrome.
Layton RG, Pontier JF, Bins GP, Sucher BJ, Runyan CM
Cleft Palate Craniofac J 2023 May;60(5):591-600. Epub 2022 Jan 19 doi: 10.1177/10556656211072762. PMID: 35044263
The foramen magnum in scaphocephaly.
Skadorwa T, Wierzbieniec O
Childs Nerv Syst 2022 Nov;38(11):2163-2170. Epub 2022 Aug 5 doi: 10.1007/s00381-022-05624-2. PMID: 35931858Free PMC Article
Iniencephaly.
Holmes LB, Toufaily MH, Westgate MN
Birth Defects Res 2018 Jan;110(2):128-133. doi: 10.1002/bdr2.1082. PMID: 29377645
The suboccipital ligament.
Alabaster K, Fred Bugg M, Splavski B, Boop FA, Arnautovic KI
J Neurosurg 2018 Jan;128(1):165-173. Epub 2017 Apr 14 doi: 10.3171/2016.10.JNS162161. PMID: 28409726
Occipital plagiocephaly.
David DJ, Menard RM
Br J Plast Surg 2000 Jul;53(5):367-77. doi: 10.1054/bjps.2000.3329. PMID: 10876272

Diagnosis

Chiari Malformation (Update on Diagnosis and Treatment).
Rosenblum JS, Pomeraniec IJ, Heiss JD
Neurol Clin 2022 May;40(2):297-307. Epub 2022 Mar 31 doi: 10.1016/j.ncl.2021.11.007. PMID: 35465876Free PMC Article
Occipital Encephalocele: Cause, Incidence, Neuroimaging and Surgical Management.
Markovic I, Bosnjakovic P, Milenkovic Z
Curr Pediatr Rev 2020;16(3):200-205. doi: 10.2174/1573396315666191018161535. PMID: 31656152Free PMC Article
Occipital plagiocephaly.
David DJ, Menard RM
Br J Plast Surg 2000 Jul;53(5):367-77. doi: 10.1054/bjps.2000.3329. PMID: 10876272
Asterion region synostosis.
Jimenez DF, Barone CM, Argamaso RV, Goodrich JT, Shprintzen RJ
Cleft Palate Craniofac J 1994 Mar;31(2):136-41. doi: 10.1597/1545-1569_1994_031_0136_ars_2.3.co_2. PMID: 8186221
Lambdoid synostosis.
Vander Kolk CA, Carson BS
Clin Plast Surg 1994 Oct;21(4):575-84. PMID: 7813157

Therapy

IgG4-Related Disease of the Craniovertebral Junction.
Park BJ, Starks R, Kirby P, Menezes AH, Dlouhy BJ
World Neurosurg 2020 Feb;134:264-271. Epub 2019 Nov 8 doi: 10.1016/j.wneu.2019.10.195. PMID: 31712115
Chiari malformation type I: related conditions.
deSouza RM, Zador Z, Frim DM
Neurol Res 2011 Apr;33(3):278-84. doi: 10.1179/016164111X12962202723922. PMID: 21513648
Cyclosporin and organ specific toxicity: clinical aspects, pharmacogenetics and perspectives.
Magnasco A, Rossi A, Catarsi P, Gusmano R, Ginevri F, Perfumo F, Ghiggeri GM
Curr Clin Pharmacol 2008 Sep;3(3):166-73. doi: 10.2174/157488408785747674. PMID: 18781903
Methyl methacrylate cranioplasty.
Azmi A, Latiff AZ, Johari A
Med J Malaysia 2004 Aug;59(3):418-21. PMID: 15727391
Common surgical pitfalls in the skull.
Keskil S, Gözil R, Calgüner E
Surg Neurol 2003 Mar;59(3):228-31; discussion 231. doi: 10.1016/s0090-3019(02)01038-8. PMID: 12681561

Prognosis

Natural History of Chiari 1 Deformity.
Venkatakrishna SSB, McClure ME, Andronikou S
J Comput Assist Tomogr 2023 Mar-Apr 01;47(2):301-306. Epub 2022 Dec 13 doi: 10.1097/RCT.0000000000001404. PMID: 36728736
Occipital Encephalocele: Cause, Incidence, Neuroimaging and Surgical Management.
Markovic I, Bosnjakovic P, Milenkovic Z
Curr Pediatr Rev 2020;16(3):200-205. doi: 10.2174/1573396315666191018161535. PMID: 31656152Free PMC Article
Occipital condyle morphometry and incidence of condylus tertius: phylogenetic and clinical significance.
Saralaya VV, Murlimanju BV, Vaderav R, Tonse M, Prameela MD, Jiji PJ
Clin Ter 2012 Nov;163(6):479-82. PMID: 23306741
Unusual venous sinuses.
Srijit D, Shipra P
Bratisl Lek Listy 2007;108(2):104-6. PMID: 17685011
Nasal encephaloceles.
Hoving EW
Childs Nerv Syst 2000 Nov;16(10-11):702-6. doi: 10.1007/s003810000339. PMID: 11151720

Clinical prediction guides

Natural History of Chiari 1 Deformity.
Venkatakrishna SSB, McClure ME, Andronikou S
J Comput Assist Tomogr 2023 Mar-Apr 01;47(2):301-306. Epub 2022 Dec 13 doi: 10.1097/RCT.0000000000001404. PMID: 36728736
Morphology of the Occipital Bones and Foramen Magnum Resulting From Premature Minor Suture Fusion in Crouzon Syndrome.
Layton RG, Pontier JF, Bins GP, Sucher BJ, Runyan CM
Cleft Palate Craniofac J 2023 May;60(5):591-600. Epub 2022 Jan 19 doi: 10.1177/10556656211072762. PMID: 35044263
The foramen magnum in scaphocephaly.
Skadorwa T, Wierzbieniec O
Childs Nerv Syst 2022 Nov;38(11):2163-2170. Epub 2022 Aug 5 doi: 10.1007/s00381-022-05624-2. PMID: 35931858Free PMC Article
Three-Dimensional Morphology and Configuration Analyses of the Craniovertebral Junction in Children with Hemifacial Microsomia.
Xu X, Chen X, Zhao SB, Jin JL, Tang XJ, Yin L, Liu W, Li C, Feng S, Zhang ZY
Spine (Phila Pa 1976) 2022 Jun 1;47(11):817-824. Epub 2022 Feb 22 doi: 10.1097/BRS.0000000000004346. PMID: 35193998
Vermian fossa or median occipital fossa revisited: Prevalence and clinical anatomy.
Kunc V, Fabik J, Kubickova B, Kachlik D
Ann Anat 2020 May;229:151458. Epub 2020 Jan 31 doi: 10.1016/j.aanat.2020.151458. PMID: 32014471

Recent systematic reviews

Pathogenesis and treatment of a giant occipital bone defect with meningoencephalocele in an NF1 child: case report and review of the literature.
Antico A, Vitulli F, Rossi A, Gaggero G, Piatelli G, Consales A
Childs Nerv Syst 2024 Jan;40(1):27-39. Epub 2023 Nov 23 doi: 10.1007/s00381-023-06232-4. PMID: 37993698
Posterior Fossa Dimensions of Chiari Malformation Patients Compared with Normal Subjects: Systematic Review and Meta-Analysis.
Botelho RV, Heringer LC, Botelho PB, Lopes RA, Waisberg J
World Neurosurg 2020 Jun;138:521-529.e2. Epub 2020 Mar 7 doi: 10.1016/j.wneu.2020.02.182. PMID: 32156591
First trimester detection of fetal open spina bifida using BS/BSOB ratio.
Sirico A, Raffone A, Lanzone A, Saccone G, Travaglino A, Sarno L, Rizzo G, Zullo F, Maruotti GM
Arch Gynecol Obstet 2020 Feb;301(2):333-340. Epub 2019 Dec 24 doi: 10.1007/s00404-019-05422-3. PMID: 31875250
Dural arteriovenous fistulas of the hypoglossal canal: systematic review on imaging anatomy, clinical findings, and endovascular management.
Spittau B, Millán DS, El-Sherifi S, Hader C, Singh TP, Motschall E, Vach W, Urbach H, Meckel S
J Neurosurg 2015 Apr;122(4):883-903. Epub 2014 Nov 21 doi: 10.3171/2014.10.JNS14377. PMID: 25415064

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