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Abnormal electrophysiology of sinoatrial node origin

MedGen UID:
868812
Concept ID:
C4023222
Anatomical Abnormality
HPO: HP:0011702

Definition

An abnormality of the sinoatrial (SA) node in the right atrium. THe SA node acts as the pacemaker of the heart. [from HPO]

Term Hierarchy

Conditions with this feature

Intellectual disability, keratoconus, febrile seizures, and sinoatrial block
MedGen UID:
324455
Concept ID:
C1836202
Disease or Syndrome
Sinus node disease and myopia
MedGen UID:
401121
Concept ID:
C1866960
Disease or Syndrome

Recent clinical studies

Etiology

Carlson SK, Patel AR, Chang PM
Card Electrophysiol Clin 2017 Jun;9(2):177-187. Epub 2017 Mar 22 doi: 10.1016/j.ccep.2017.02.002. PMID: 28457234
Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413
Gonzalez RP, Scheinman MM, Lesh MD, Helmy I, Torres V, Van Hare GF
Am Heart J 1994 Jul;128(1):147-56. doi: 10.1016/0002-8703(94)90021-3. PMID: 8017268
Cassidy DM, Vassallo JA, Buxton AE, Doherty JU, Marchlinski FE, Josephson ME
Am J Cardiol 1985 Mar 1;55(6):713-6. doi: 10.1016/0002-9149(85)90142-0. PMID: 3976514
Lüderitz B
Pacing Clin Electrophysiol 1982 Jul;5(4):548-60. doi: 10.1111/j.1540-8159.1982.tb02277.x. PMID: 6180398

Diagnosis

Nagarakanti R, Saksena S
J Interv Card Electrophysiol 2016 Jun;46(1):55-61. Epub 2015 Nov 25 doi: 10.1007/s10840-015-0072-7. PMID: 26607480
Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413
Cossú SF, Steinberg JS
Prog Cardiovasc Dis 1998 Jul-Aug;41(1):51-63. doi: 10.1016/s0033-0620(98)80022-4. PMID: 9717859
Byrum CJ, Bove EL, Sondheimer HM, Kavey RE, Blackman MS
Am J Cardiol 1987 Aug 1;60(4):346-50. doi: 10.1016/0002-9149(87)90240-2. PMID: 3618494
Lüderitz B
Pacing Clin Electrophysiol 1982 Jul;5(4):548-60. doi: 10.1111/j.1540-8159.1982.tb02277.x. PMID: 6180398

Therapy

Cossú SF, Steinberg JS
Prog Cardiovasc Dis 1998 Jul-Aug;41(1):51-63. doi: 10.1016/s0033-0620(98)80022-4. PMID: 9717859
Gonzalez RP, Scheinman MM, Lesh MD, Helmy I, Torres V, Van Hare GF
Am Heart J 1994 Jul;128(1):147-56. doi: 10.1016/0002-8703(94)90021-3. PMID: 8017268
Lüderitz B
Pacing Clin Electrophysiol 1982 Jul;5(4):548-60. doi: 10.1111/j.1540-8159.1982.tb02277.x. PMID: 6180398

Prognosis

Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413
Gonzalez RP, Scheinman MM, Lesh MD, Helmy I, Torres V, Van Hare GF
Am Heart J 1994 Jul;128(1):147-56. doi: 10.1016/0002-8703(94)90021-3. PMID: 8017268
Cassidy DM, Vassallo JA, Buxton AE, Doherty JU, Marchlinski FE, Josephson ME
Am J Cardiol 1985 Mar 1;55(6):713-6. doi: 10.1016/0002-9149(85)90142-0. PMID: 3976514

Clinical prediction guides

Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413

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