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Spontaneous pain sensation

MedGen UID:
869264
•Concept ID:
C4023690
•
Sign or Symptom
HPO: HP:0010833

Definition

Spontaneous pain is a kind of neuropathic pain which occurs without an identifiable trigger. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpontaneous pain sensation

Professional guidelines

PubMed

Pain assessment and management in Italian Haemophilia Centres.
Di Minno MND, Santoro C, Corcione A, Di Minno G, Martinelli M, Mancuso ME, Acone B, Molinari AC, Passeri EV, Rocino A, Santoro RC, Tagliaferri A, Mattia C; HAEMODOL Study Group (Appendix 1)
Blood Transfus 2021 Jul;19(4):335-342. Epub 2020 Nov 27 doi: 10.2450/2020.0085-20. PMID: 33263519Free PMC Article
Peyronie's disease: Contemporary evaluation and management.
Ziegelmann MJ, Bajic P, Levine LA
Int J Urol 2020 Jun;27(6):504-516. Epub 2020 Apr 6 doi: 10.1111/iju.14230. PMID: 32253786
Burning mouth syndrome: a review of etiology, diagnosis, and management.
Teruel A, Patel S
Gen Dent 2019 Mar-Apr;67(2):24-29. PMID: 30875303

Recent clinical studies

Etiology

Prevention of post-herpetic neuralgia using transcutaneous electrical nerve stimulation.
Stepanović A, Kolšek M, Kersnik J, Erčulj V
Wien Klin Wochenschr 2015 May;127(9-10):369-74. Epub 2014 Dec 4 doi: 10.1007/s00508-014-0669-3. PMID: 25471002
Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study.
Predel HG, Giannetti B, Koll R, Bulitta M, Staiger C
Phytomedicine 2005 Nov;12(10):707-14. doi: 10.1016/j.phymed.2005.06.001. PMID: 16323288
Perioperative intravenous adenosine infusion to extend postoperative analgesia in brachial plexus block.
Apan A, Ozcan S, Buyukkocak U, Anbarci O, Basar H
Eur J Anaesthesiol 2003 Nov;20(11):916-9. doi: 10.1017/s0265021503001479. PMID: 14649345
Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.
Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group
Diabetes Care 2001 Oct;24(10):1776-82. doi: 10.2337/diacare.24.10.1776. PMID: 11574441

Therapy

Prevention of post-herpetic neuralgia using transcutaneous electrical nerve stimulation.
Stepanović A, Kolšek M, Kersnik J, Erčulj V
Wien Klin Wochenschr 2015 May;127(9-10):369-74. Epub 2014 Dec 4 doi: 10.1007/s00508-014-0669-3. PMID: 25471002
Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study.
Predel HG, Giannetti B, Koll R, Bulitta M, Staiger C
Phytomedicine 2005 Nov;12(10):707-14. doi: 10.1016/j.phymed.2005.06.001. PMID: 16323288
Perioperative intravenous adenosine infusion to extend postoperative analgesia in brachial plexus block.
Apan A, Ozcan S, Buyukkocak U, Anbarci O, Basar H
Eur J Anaesthesiol 2003 Nov;20(11):916-9. doi: 10.1017/s0265021503001479. PMID: 14649345
Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.
Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group
Diabetes Care 2001 Oct;24(10):1776-82. doi: 10.2337/diacare.24.10.1776. PMID: 11574441
Capsaicin-induced central facilitation of a nociceptive flexion reflex in humans.
Grönroos M, Pertovaara A
Neurosci Lett 1993 Sep 3;159(1-2):215-8. doi: 10.1016/0304-3940(93)90837-b. PMID: 8264971

Prognosis

Prevention of post-herpetic neuralgia using transcutaneous electrical nerve stimulation.
Stepanović A, Kolšek M, Kersnik J, Erčulj V
Wien Klin Wochenschr 2015 May;127(9-10):369-74. Epub 2014 Dec 4 doi: 10.1007/s00508-014-0669-3. PMID: 25471002
Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.
Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group
Diabetes Care 2001 Oct;24(10):1776-82. doi: 10.2337/diacare.24.10.1776. PMID: 11574441

Clinical prediction guides

Prevention of post-herpetic neuralgia using transcutaneous electrical nerve stimulation.
Stepanović A, Kolšek M, Kersnik J, Erčulj V
Wien Klin Wochenschr 2015 May;127(9-10):369-74. Epub 2014 Dec 4 doi: 10.1007/s00508-014-0669-3. PMID: 25471002
Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study.
Predel HG, Giannetti B, Koll R, Bulitta M, Staiger C
Phytomedicine 2005 Nov;12(10):707-14. doi: 10.1016/j.phymed.2005.06.001. PMID: 16323288
Perioperative intravenous adenosine infusion to extend postoperative analgesia in brachial plexus block.
Apan A, Ozcan S, Buyukkocak U, Anbarci O, Basar H
Eur J Anaesthesiol 2003 Nov;20(11):916-9. doi: 10.1017/s0265021503001479. PMID: 14649345

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