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Hypoplasia of the small intestine

MedGen UID:
870831
•Concept ID:
C4025291
•
Anatomical Abnormality
Synonym: Underdeveloped small intestine
 
HPO: HP:0004790

Definition

Underdevelopment of the small intestine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoplasia of the small intestine

Conditions with this feature

Acrocephalopolydactyly
MedGen UID:
501209
•Concept ID:
C3495588
•
Disease or Syndrome
Acrocephalopolydactylous dysplasia, or Elejalde syndrome, is a lethal multiple congenital disorder characterized by increased birth weight, globular body with thick skin, organomegaly, and fibrosis in multiple tissues (summary by Phadke et al., 2011).
See: Condition Record
Acrocephalopolydactyly

Professional guidelines

PubMed

Small Intestinal Bacterial Overgrowth-Pathophysiology and Its Implications for Definition and Management.
Bushyhead D, Quigley EMM
Gastroenterology 2022 Sep;163(3):593-607. Epub 2022 Apr 7 doi: 10.1053/j.gastro.2022.04.002. PMID: 35398346
Emergency Medicine Evaluation and Management of Small Bowel Obstruction: Evidence-Based Recommendations.
Long B, Robertson J, Koyfman A
J Emerg Med 2019 Feb;56(2):166-176. Epub 2018 Dec 6 doi: 10.1016/j.jemermed.2018.10.024. PMID: 30527563
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845

Recent clinical studies

Etiology

Small Intestinal Bacterial Overgrowth-Pathophysiology and Its Implications for Definition and Management.
Bushyhead D, Quigley EMM
Gastroenterology 2022 Sep;163(3):593-607. Epub 2022 Apr 7 doi: 10.1053/j.gastro.2022.04.002. PMID: 35398346
Reference curves for the normal fetal small bowel and colon diameters; their usefulness in fetuses with suspected dilated bowel.
Lap CC, Voskuilen CS, Pistorius LR, Mulder EJH, Visser GHA, Manten GTR
J Matern Fetal Neonatal Med 2020 Feb;33(4):633-638. Epub 2019 Jan 6 doi: 10.1080/14767058.2018.1498837. PMID: 29985072
Assessment of Crohn's disease-associated small bowel strictures and fibrosis on cross-sectional imaging: a systematic review.
Bettenworth D, Bokemeyer A, Baker M, Mao R, Parker CE, Nguyen T, Ma C, Panés J, Rimola J, Fletcher JG, Jairath V, Feagan BG, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium.
Gut 2019 Jun;68(6):1115-1126. Epub 2019 Apr 3 doi: 10.1136/gutjnl-2018-318081. PMID: 30944110Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Malignant tumours of the small intestine.
Reynolds I, Healy P, Mcnamara DA
Surgeon 2014 Oct;12(5):263-70. Epub 2014 Mar 14 doi: 10.1016/j.surge.2014.02.003. PMID: 24637026

Diagnosis

Intestinal Atresias.
Rich BS, Bornstein E, Dolgin SE
Pediatr Rev 2022 May 1;43(5):266-274. doi: 10.1542/pir.2021-005177. PMID: 35490204
Small Intestinal Bacterial Overgrowth-Pathophysiology and Its Implications for Definition and Management.
Bushyhead D, Quigley EMM
Gastroenterology 2022 Sep;163(3):593-607. Epub 2022 Apr 7 doi: 10.1053/j.gastro.2022.04.002. PMID: 35398346
Small and Large Intestine (I): Malabsorption of Nutrients.
Montoro-Huguet MA, Belloc B, Domínguez-Cajal M
Nutrients 2021 Apr 11;13(4) doi: 10.3390/nu13041254. PMID: 33920345Free PMC Article
Emergency Medicine Evaluation and Management of Small Bowel Obstruction: Evidence-Based Recommendations.
Long B, Robertson J, Koyfman A
J Emerg Med 2019 Feb;56(2):166-176. Epub 2018 Dec 6 doi: 10.1016/j.jemermed.2018.10.024. PMID: 30527563
Small intestinal bacterial overgrowth syndrome.
Bures J, Cyrany J, Kohoutova D, Förstl M, Rejchrt S, Kvetina J, Vorisek V, Kopacova M
World J Gastroenterol 2010 Jun 28;16(24):2978-90. doi: 10.3748/wjg.v16.i24.2978. PMID: 20572300Free PMC Article

Therapy

AGA Clinical Practice Update on Small Intestinal Bacterial Overgrowth: Expert Review.
Quigley EMM, Murray JA, Pimentel M
Gastroenterology 2020 Oct;159(4):1526-1532. Epub 2020 Jul 15 doi: 10.1053/j.gastro.2020.06.090. PMID: 32679220
Medical and surgical management of short bowel syndrome.
Billiauws L, Maggiori L, Joly F, Panis Y
J Visc Surg 2018 Sep;155(4):283-291. Epub 2018 Jul 21 doi: 10.1016/j.jviscsurg.2017.12.012. PMID: 30041905
Heavy Chain Disease of the Small Bowel.
Bianchi G, Sohani AR
Curr Gastroenterol Rep 2018 Jan 25;20(1):3. doi: 10.1007/s11894-018-0608-y. PMID: 29372346
ACG clinical guidelines: diagnosis and management of celiac disease.
Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA; American College of Gastroenterology
Am J Gastroenterol 2013 May;108(5):656-76; quiz 677. Epub 2013 Apr 23 doi: 10.1038/ajg.2013.79. PMID: 23609613Free PMC Article
Whipple's disease.
Ratnaike RN
Postgrad Med J 2000 Dec;76(902):760-6. doi: 10.1136/pmj.76.902.760. PMID: 11085766Free PMC Article

Prognosis

Reference curves for the normal fetal small bowel and colon diameters; their usefulness in fetuses with suspected dilated bowel.
Lap CC, Voskuilen CS, Pistorius LR, Mulder EJH, Visser GHA, Manten GTR
J Matern Fetal Neonatal Med 2020 Feb;33(4):633-638. Epub 2019 Jan 6 doi: 10.1080/14767058.2018.1498837. PMID: 29985072
Assessment of Crohn's disease-associated small bowel strictures and fibrosis on cross-sectional imaging: a systematic review.
Bettenworth D, Bokemeyer A, Baker M, Mao R, Parker CE, Nguyen T, Ma C, Panés J, Rimola J, Fletcher JG, Jairath V, Feagan BG, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium.
Gut 2019 Jun;68(6):1115-1126. Epub 2019 Apr 3 doi: 10.1136/gutjnl-2018-318081. PMID: 30944110Free PMC Article
Microscopic enteritis: Bucharest consensus.
Rostami K, Aldulaimi D, Holmes G, Johnson MW, Robert M, Srivastava A, Fléjou JF, Sanders DS, Volta U, Derakhshan MH, Going JJ, Becheanu G, Catassi C, Danciu M, Materacki L, Ghafarzadegan K, Ishaq S, Rostami-Nejad M, Peña AS, Bassotti G, Marsh MN, Villanacci V
World J Gastroenterol 2015 Mar 7;21(9):2593-604. doi: 10.3748/wjg.v21.i9.2593. PMID: 25759526Free PMC Article
Malignant tumours of the small intestine.
Reynolds I, Healy P, Mcnamara DA
Surgeon 2014 Oct;12(5):263-70. Epub 2014 Mar 14 doi: 10.1016/j.surge.2014.02.003. PMID: 24637026
Small intestinal bacterial overgrowth syndrome.
Bures J, Cyrany J, Kohoutova D, Förstl M, Rejchrt S, Kvetina J, Vorisek V, Kopacova M
World J Gastroenterol 2010 Jun 28;16(24):2978-90. doi: 10.3748/wjg.v16.i24.2978. PMID: 20572300Free PMC Article

Clinical prediction guides

Crohn's disease.
Dolinger M, Torres J, Vermeire S
Lancet 2024 Mar 23;403(10432):1177-1191. Epub 2024 Mar 1 doi: 10.1016/S0140-6736(23)02586-2. PMID: 38437854
Reference curves for the normal fetal small bowel and colon diameters; their usefulness in fetuses with suspected dilated bowel.
Lap CC, Voskuilen CS, Pistorius LR, Mulder EJH, Visser GHA, Manten GTR
J Matern Fetal Neonatal Med 2020 Feb;33(4):633-638. Epub 2019 Jan 6 doi: 10.1080/14767058.2018.1498837. PMID: 29985072
Capsule endoscopy for small-intestinal disorders: Current status.
Hosoe N, Takabayashi K, Ogata H, Kanai T
Dig Endosc 2019 Sep;31(5):498-507. Epub 2019 Feb 10 doi: 10.1111/den.13346. PMID: 30656743
Microscopic enteritis: Bucharest consensus.
Rostami K, Aldulaimi D, Holmes G, Johnson MW, Robert M, Srivastava A, Fléjou JF, Sanders DS, Volta U, Derakhshan MH, Going JJ, Becheanu G, Catassi C, Danciu M, Materacki L, Ghafarzadegan K, Ishaq S, Rostami-Nejad M, Peña AS, Bassotti G, Marsh MN, Villanacci V
World J Gastroenterol 2015 Mar 7;21(9):2593-604. doi: 10.3748/wjg.v21.i9.2593. PMID: 25759526Free PMC Article
The use of SmartPill for gastric monitoring.
Hasler WL
Expert Rev Gastroenterol Hepatol 2014 Aug;8(6):587-600. Epub 2014 May 31 doi: 10.1586/17474124.2014.922869. PMID: 24881810

Recent systematic reviews

Endoscopic Evaluation of the Ileal Pouch.
Shen B
Dis Colon Rectum 2024 Jun 1;67(S1):S52-S69. Epub 2024 Jan 25 doi: 10.1097/DCR.0000000000003269. PMID: 38276962
Assessment of Crohn's disease-associated small bowel strictures and fibrosis on cross-sectional imaging: a systematic review.
Bettenworth D, Bokemeyer A, Baker M, Mao R, Parker CE, Nguyen T, Ma C, Panés J, Rimola J, Fletcher JG, Jairath V, Feagan BG, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium.
Gut 2019 Jun;68(6):1115-1126. Epub 2019 Apr 3 doi: 10.1136/gutjnl-2018-318081. PMID: 30944110Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Imaging spectrum of nonneoplastic duodenal diseases.
Srisajjakul S, Prapaisilp P, Bangchokdee S
Clin Imaging 2016 Nov-Dec;40(6):1173-1181. Epub 2016 Aug 6 doi: 10.1016/j.clinimag.2016.08.007. PMID: 27572283
Accuracy of prenatal ultrasound in detecting jejunal and ileal atresia: systematic review and meta-analysis.
Virgone C, D'antonio F, Khalil A, Jonh R, Manzoli L, Giuliani S
Ultrasound Obstet Gynecol 2015 May;45(5):523-9. doi: 10.1002/uog.14651. PMID: 25157626

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