U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal pericardium morphology

MedGen UID:
871268
•Concept ID:
C4025754
•
Anatomical Abnormality
Synonym: Abnormality of the pericardium
 
HPO: HP:0001697

Definition

An abnormality of the pericardium, i.e., of the fluid filled sac that surrounds the heart and the proximal ends of the aorta, vena cava, and the pulmonary artery. [from HPO]

Professional guidelines

PubMed

Case series, contemporary review and imaging guided diagnostic and management approach of congenital pericardial defects.
Khayata M, Alkharabsheh S, Shah NP, Verma BR, Gentry JL, Summers M, Xu B, Asher C, Klein AL
Open Heart 2020;7(1):e001103. Epub 2020 Jan 8 doi: 10.1136/openhrt-2019-001103. PMID: 32076559Free PMC Article
Congenital Absence of the Pericardium: A Systematic Approach to Diagnosis and Management.
Xu B, Betancor J, Asher C, Rosario A, Klein A
Cardiology 2017;136(4):270-278. Epub 2016 Dec 7 doi: 10.1159/000452441. PMID: 27923231
Pericardial disease: diagnosis and management.
Khandaker MH, Espinosa RE, Nishimura RA, Sinak LJ, Hayes SN, Melduni RM, Oh JK
Mayo Clin Proc 2010 Jun;85(6):572-93. doi: 10.4065/mcp.2010.0046. PMID: 20511488Free PMC Article

Recent clinical studies

Etiology

The Role of Inflammation in Epicardial Adipose Tissue in Heart Diseases.
Matloch Z, Cinkajzlova A, Mraz M, Haluzik M
Curr Pharm Des 2018;24(3):297-309. doi: 10.2174/1381612824666180110102125. PMID: 29318960
Congenital Abnormalities of the Pericardium.
Parmar YJ, Shah AB, Poon M, Kronzon I
Cardiol Clin 2017 Nov;35(4):601-614. doi: 10.1016/j.ccl.2017.07.012. PMID: 29025550
Coronary arterial development: a review of normal and congenitally anomalous patterns.
Lluri G, Aboulhosn J
Clin Cardiol 2014 Feb;37(2):126-30. Epub 2014 Jan 7 doi: 10.1002/clc.22237. PMID: 24399787Free PMC Article
Childhood obesity and cardiovascular dysfunction.
Cote AT, Harris KC, Panagiotopoulos C, Sandor GG, Devlin AM
J Am Coll Cardiol 2013 Oct 8;62(15):1309-19. Epub 2013 Aug 14 doi: 10.1016/j.jacc.2013.07.042. PMID: 23954339
Bilateral congenital diaphragmatic hernia.
Neville HL, Jaksic T, Wilson JM, Lally PA, Hardin WD Jr, Hirschl RB, Lally KP; Congenital Diaphragmatic Hernia Study Group
J Pediatr Surg 2003 Mar;38(3):522-4. doi: 10.1053/jpsu.2003.50092. PMID: 12632380

Diagnosis

Imaging of Pericardial Disease.
Kligerman S
Radiol Clin North Am 2019 Jan;57(1):179-199. doi: 10.1016/j.rcl.2018.09.001. PMID: 30454812
Congenital Abnormalities of the Pericardium.
Parmar YJ, Shah AB, Poon M, Kronzon I
Cardiol Clin 2017 Nov;35(4):601-614. doi: 10.1016/j.ccl.2017.07.012. PMID: 29025550
Pathophysiology of the Pericardium.
Hoit BD
Prog Cardiovasc Dis 2017 Jan-Feb;59(4):341-348. Epub 2016 Dec 1 doi: 10.1016/j.pcad.2016.11.001. PMID: 27916673
Pericardial diseases.
Dudzinski DM, Mak GS, Hung JW
Curr Probl Cardiol 2012 Mar;37(3):75-118. doi: 10.1016/j.cpcardiol.2011.10.002. PMID: 22289657
MR imaging of the pericardium.
Misselt AJ, Harris SR, Glockner J, Feng D, Syed IS, Araoz PA
Magn Reson Imaging Clin N Am 2008 May;16(2):185-99, vii. doi: 10.1016/j.mric.2008.02.011. PMID: 18474326

Therapy

ACR Appropriateness Criteria® Dyspnea-Suspected Cardiac Origin (Ischemia Already Excluded): 2021 Update.
Expert Panel on Cardiac Imaging, Bolen MA, Bin Saeedan MN, Rajiah P, Ahmad S, Dibble EH, Diercks DB, El-Sherief AH, Farzaneh-Far A, Francois CJ, Galizia MS, Hanneman K, Inacio JR, Johri AM, Khosa F, Krishnamurthy R, Lenge de Rosen V, Singh SP, Teng K, Villines TC, Young PM, Zimmerman SL, Abbara S
J Am Coll Radiol 2022 May;19(5S):S37-S52. doi: 10.1016/j.jacr.2022.02.014. PMID: 35550804
Histology of Pericardial Tissue Substitutes Used in Congenital Heart Surgery.
Majeed A, Baird C, Borisuk MJ, Sanders SP, Padera RF Jr
Pediatr Dev Pathol 2016 Sep/Oct;19(5):383-388. Epub 2015 Oct 22 doi: 10.2350/15-08-1696-OA.1. PMID: 26492092
Fibrosis, Connexin-43, and Conduction Abnormalities in the Brugada Syndrome.
Nademanee K, Raju H, de Noronha SV, Papadakis M, Robinson L, Rothery S, Makita N, Kowase S, Boonmee N, Vitayakritsirikul V, Ratanarapee S, Sharma S, van der Wal AC, Christiansen M, Tan HL, Wilde AA, Nogami A, Sheppard MN, Veerakul G, Behr ER
J Am Coll Cardiol 2015 Nov 3;66(18):1976-1986. doi: 10.1016/j.jacc.2015.08.862. PMID: 26516000Free PMC Article
Tuberculous effusive-constrictive pericarditis.
Russell JB, Syed FF, Ntsekhe M, Mayosi BM, Moosa S, Tshifularo M, Smedema JP
Cardiovasc J Afr 2008 Jul-Aug;19(4):200-1. PMID: 18776964
Cardiac effects of noncardiac neoplasms.
Schoen FJ, Berger BM, Guerina NG
Cardiol Clin 1984 Nov;2(4):657-70. PMID: 6400009

Prognosis

Current advances in cardiac magnetic resonance imaging in systemic sclerosis.
Agoston-Coldea L, Zlibut A, Revnic R, Florea M, Muntean L
Eur Rev Med Pharmacol Sci 2021 May;25(10):3718-3736. doi: 10.26355/eurrev_202105_25940. PMID: 34109581
Multimodality Imaging for the Assessment of Pericardial Diseases.
Chetrit M, Xu B, Verma BR, Klein AL
Curr Cardiol Rep 2019 Apr 16;21(5):41. doi: 10.1007/s11886-019-1115-y. PMID: 30993456
Role of non-invasive imaging in the work-up of cardiomyopathies.
Tummala LS, Young RK, Singh T, Jani S, Srichai MB
Curr Atheroscler Rep 2015 Mar;17(3):486. doi: 10.1007/s11883-014-0486-1. PMID: 25637041
Coronary arterial development: a review of normal and congenitally anomalous patterns.
Lluri G, Aboulhosn J
Clin Cardiol 2014 Feb;37(2):126-30. Epub 2014 Jan 7 doi: 10.1002/clc.22237. PMID: 24399787Free PMC Article
Cardiovascular magnetic resonance in pericardial diseases.
Bogaert J, Francone M
J Cardiovasc Magn Reson 2009 May 4;11(1):14. doi: 10.1186/1532-429X-11-14. PMID: 19413898Free PMC Article

Clinical prediction guides

Recurrent Tumor Suppressor Alterations in Primary Pericardial Mesothelioma.
Schaefer IM, Mariño-Enríquez A, Hammer MM, Padera RF, Sholl LM
Mod Pathol 2023 Sep;36(9):100237. Epub 2023 Jun 8 doi: 10.1016/j.modpat.2023.100237. PMID: 37295554Free PMC Article
The Chicken as a Model Organism to Study Heart Development.
Wittig JG, Münsterberg A
Cold Spring Harb Perspect Biol 2020 Aug 3;12(8) doi: 10.1101/cshperspect.a037218. PMID: 31767650Free PMC Article
Extrapelvic endometriosis: a rare entity or an under diagnosed condition?
Machairiotis N, Stylianaki A, Dryllis G, Zarogoulidis P, Kouroutou P, Tsiamis N, Katsikogiannis N, Sarika E, Courcoutsakis N, Tsiouda T, Gschwendtner A, Zarogoulidis K, Sakkas L, Baliaka A, Machairiotis C
Diagn Pathol 2013 Dec 2;8:194. doi: 10.1186/1746-1596-8-194. PMID: 24294950Free PMC Article
Childhood obesity and cardiovascular dysfunction.
Cote AT, Harris KC, Panagiotopoulos C, Sandor GG, Devlin AM
J Am Coll Cardiol 2013 Oct 8;62(15):1309-19. Epub 2013 Aug 14 doi: 10.1016/j.jacc.2013.07.042. PMID: 23954339
Cardiovascular magnetic resonance in pericardial diseases.
Bogaert J, Francone M
J Cardiovasc Magn Reson 2009 May 4;11(1):14. doi: 10.1186/1532-429X-11-14. PMID: 19413898Free PMC Article

Recent systematic reviews

The Outcomes of Surgical Separation in Thoracopagus Twins with Conjoined Hearts: An Analysis of the Literature.
Collins RT 2nd, O'Connor MJ
Pediatr Cardiol 2021 Apr;42(4):875-882. Epub 2021 Apr 15 doi: 10.1007/s00246-021-02555-8. PMID: 33856497
The Spectrum of Pericardial Involvement in Giant Cell Arteritis and Polymyalgia Rheumatica: A Systematic Review of Literature.
Fayyaz B, Rehman HJ
J Clin Rheumatol 2021 Jan 1;27(1):5-10. doi: 10.1097/RHU.0000000000001140. PMID: 31483352
A systematic review of the efficacy and safety of intrapericardial fibrinolysis in patients with pericardial effusion.
Wiyeh AB, Ochodo EA, Wiysonge CS, Kakia A, Awotedu AA, Ristic A, Mayosi BM
Int J Cardiol 2018 Jan 1;250:223-228. Epub 2017 Nov 6 doi: 10.1016/j.ijcard.2017.10.049. PMID: 29107356
Does echocardiography play a role in the clinical diagnosis of congenital absence of pericardium? A case presentation and a systematic review.
Centola M, Longo M, De Marco F, Cremonesi G, Marconi M, Danzi GB
J Cardiovasc Med (Hagerstown) 2009 Sep;10(9):687-92. doi: 10.2459/JCM.0b013e32832b3d4a. PMID: 19448561

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...