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Syringomyelia and Hydromyelia

MedGen UID:: 888087
•Concept ID:: C4053961
•: Disease or Syndrome

Definition

Syringomyelia associated with accumulation of cerebrospinal fluid in the spinal cord. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVSyringomyelia and Hydromyelia

Morphological central nervous system abnormality
- Abnormal neural tube morphology
  - Neural tube defect
    - Closed neural tube defect
      - Myelopathy
        Syringomyelia
        Syringomyelia and Hydromyelia

Professional guidelines

PubMed

Treatment of posttraumatic syringomyelia: evidence from a systematic review.

Kleindienst A, Laut FM, Roeckelein V, Buchfelder M, Dodoo-Schittko F
Acta Neurochir (Wien) 2020 Oct;162(10):2541-2556. Epub 2020 Aug 20 doi: 10.1007/s00701-020-04529-w. PMID: 32820376 Free PMC Article

Hydromyelia: clinical presentation and comparison of modalities of treatment.

Schlesinger EB, Antunes JL, Michelsen WJ, Louis KM
Neurosurgery 1981 Oct;9(4):356-65. doi: 10.1227/00006123-198110000-00002. PMID: 7301079

See all (2)

Recent clinical studies

Etiology

Terminal syringomyelia associated with lumbar limited dorsal myeloschisis.

Morioka T, Murakami N, Yanagida H, Yamaguchi T, Noguchi Y, Takahata Y, Tsukamoto A, Suzuki SO
Childs Nerv Syst 2020 Apr;36(4):819-826. Epub 2019 Jul 17 doi: 10.1007/s00381-019-04297-8. PMID: 31317225

Chiari Malformations.

Mancarella C, Delfini R, Landi A
Acta Neurochir Suppl 2019;125:89-95. doi: 10.1007/978-3-319-62515-7_13. PMID: 30610307

Syringomyelia: a practical, clinical concept for classification.

Blegvad C, Grotenhuis JA, Juhler M
Acta Neurochir (Wien) 2014 Nov;156(11):2127-38. Epub 2014 Sep 19 doi: 10.1007/s00701-014-2229-z. PMID: 25236931

Pre- and post-operative hydromyelia in spinal dysraphism.

Scatliff JH, Hayward R, Armao D, Kwon L
Pediatr Radiol 2005 Mar;35(3):282-9. Epub 2004 Oct 15 doi: 10.1007/s00247-004-1338-x. PMID: 15490146

Chiari I malformations and hydromyelia--complications.

Menezes AH
Pediatr Neurosurg 1991-1992;17(3):146-54. doi: 10.1159/000120586. PMID: 1819330

See all (21)

Diagnosis

Syringomyelia and hydromyelia: Current understanding and neurosurgical management.

Leclerc A, Matveeff L, Emery E
Rev Neurol (Paris) 2021 May;177(5):498-507. Epub 2020 Aug 18 doi: 10.1016/j.neurol.2020.07.004. PMID: 32826067

Treatment of posttraumatic syringomyelia: evidence from a systematic review.

Chiari Malformations.

Mancarella C, Delfini R, Landi A
Acta Neurochir Suppl 2019;125:89-95. doi: 10.1007/978-3-319-62515-7_13. PMID: 30610307

Defining the line between hydromyelia and syringomyelia. A differentiation is possible based on electrophysiological and magnetic resonance imaging studies.

Roser F, Ebner FH, Sixt C, Hagen JM, Tatagiba MS
Acta Neurochir (Wien) 2010 Feb;152(2):213-9; discussion 219. Epub 2009 Jun 16 doi: 10.1007/s00701-009-0427-x. PMID: 19533016

Hydromyelia: a critical review.

Wisoff JH
Childs Nerv Syst 1988 Feb;4(1):1-8. doi: 10.1007/BF00274073. PMID: 3042131

See all (40)

Therapy

The Management of Idiopathic and Refractory Syringomyelia.

Gallo P, Kaliaperumal C
Adv Tech Stand Neurosurg 2022;45:317-338. doi: 10.1007/978-3-030-99166-1_10. PMID: 35976455

Treatment of posttraumatic syringomyelia: evidence from a systematic review.

US of the spinal cord in newborns: spectrum of normal findings, variants, congenital anomalies, and acquired diseases.

Unsinn KM, Geley T, Freund MC, Gassner I
Radiographics 2000 Jul-Aug;20(4):923-38. doi: 10.1148/radiographics.20.4.g00jl06923. PMID: 10903684

The hazardous jungle of topical steroids.

Jinkins JR, Bashir R, Al-Mefty O, Al-Kawi MZ, Fox JL
Lancet 1977 Sep 3;2(8036):487-8. PMID: 70693 Free PMC Article

Iodoventriculography in hydromyelia.

Tjaden RJ, Ethier R, Vezina JL, Melançon D
J Can Assoc Radiol 1969 Dec;20(4):265-8. PMID: 4312232

See all (7)

Prognosis

Terminal syringomyelia associated with lumbar limited dorsal myeloschisis.

Morioka T, Murakami N, Yanagida H, Yamaguchi T, Noguchi Y, Takahata Y, Tsukamoto A, Suzuki SO
Childs Nerv Syst 2020 Apr;36(4):819-826. Epub 2019 Jul 17 doi: 10.1007/s00381-019-04297-8. PMID: 31317225

Clinical Relevance of Preoperative MRI in Adolescent Idiopathic Scoliosis: Is Hydromyelia a Predictive Factor of Intraoperative Electrophysiological Monitoring Alterations?

Scaramuzzo L, Giudici F, Archetti M, Minoia L, Zagra A, Bongetta D
Clin Spine Surg 2019 May;32(4):E183-E187. doi: 10.1097/BSD.0000000000000820. PMID: 30913042

The pathogenesis of syringomyelia associated with lesions at the foramen magnum: a critical review of existing theories and proposal of a new hypothesis.

Levine DN
J Neurol Sci 2004 May 15;220(1-2):3-21. doi: 10.1016/j.jns.2004.01.014. PMID: 15140600

Chiari I malformations and hydromyelia--complications.

Menezes AH
Pediatr Neurosurg 1991-1992;17(3):146-54. doi: 10.1159/000120586. PMID: 1819330

Hydromyelia: a critical review.

Wisoff JH
Childs Nerv Syst 1988 Feb;4(1):1-8. doi: 10.1007/BF00274073. PMID: 3042131

See all (18)

Clinical prediction guides

Treatment of posttraumatic syringomyelia: evidence from a systematic review.

Syringomyelia in Patient with Concurrent Posttraumatic Hydrocephalus and Tethered Spinal Cord: Implications for Surgical Management.

Li Y, Green B
World Neurosurg 2020 Jun;138:163-168. Epub 2020 Mar 7 doi: 10.1016/j.wneu.2020.02.179. PMID: 32156596

Clinical Relevance of Preoperative MRI in Adolescent Idiopathic Scoliosis: Is Hydromyelia a Predictive Factor of Intraoperative Electrophysiological Monitoring Alterations?

Scaramuzzo L, Giudici F, Archetti M, Minoia L, Zagra A, Bongetta D
Clin Spine Surg 2019 May;32(4):E183-E187. doi: 10.1097/BSD.0000000000000820. PMID: 30913042

Effects of posterior fossa decompression with and without duraplasty on Chiari malformation-associated hydromyelia.

Munshi I, Frim D, Stine-Reyes R, Weir BK, Hekmatpanah J, Brown F
Neurosurgery 2000 Jun;46(6):1384-9; discussion 1389-90. doi: 10.1097/00006123-200006000-00018. PMID: 10834643

Treatment of hydromyelia in spina bifida.

Caldarelli M, Di Rocco C, La Marca F
Surg Neurol 1998 Nov;50(5):411-20. doi: 10.1016/s0090-3019(97)00457-6. PMID: 9842864

See all (9)