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Astrocytoma, increased risk of

MedGen UID:
897068
•Concept ID:
C4228333
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAstrocytoma, increased risk of

Professional guidelines

PubMed

Epidemiology, biology, and management of venous thromboembolism in gliomas: An interdisciplinary review.
Jo J, Diaz M, Horbinski C, Mackman N, Bagley S, Broekman M, Rak J, Perry J, Pabinger I, Key NS, Schiff D
Neuro Oncol 2023 Aug 3;25(8):1381-1394. doi: 10.1093/neuonc/noad059. PMID: 37100086Free PMC Article
A Population-Based Study of Treatment and Survival in Older Glioma Patients.
Reiner AS, Lobaugh SM, Gonen S, Diamond EL, Panageas KS
JNCI Cancer Spectr 2022 Jan 5;6(1) doi: 10.1093/jncics/pkac010. PMID: 35699501Free PMC Article
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia.
Puxeddu M, Shen H, Bai R, Coluccia A, Bufano M, Nalli M, Sebastiani J, Brancaccio D, Da Pozzo E, Tremolanti C, Martini C, Orlando V, Biagioni S, Sinicropi MS, Ceramella J, Iacopetta D, Coluccia AML, Hamel E, Liu T, Silvestri R, La Regina G
Eur J Med Chem 2021 Oct 5;221:113532. Epub 2021 May 5 doi: 10.1016/j.ejmech.2021.113532. PMID: 34052717

Recent clinical studies

Etiology

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Identification of a single cell-based signature for predicting prognosis risk and immunotherapy response in patients with glioblastoma.
Dai Z, Zhang N, Zhou R, Zhang H, Zhang L, Wang Z, Zeng W, Luo P, Zhang J, Liu Z, Cheng Q
Clin Immunol 2023 Jun;251:109345. Epub 2023 Apr 24 doi: 10.1016/j.clim.2023.109345. PMID: 37100336
Multifunctional mRNA-Based CAR T Cells Display Promising Antitumor Activity Against Glioblastoma.
Meister H, Look T, Roth P, Pascolo S, Sahin U, Lee S, Hale BD, Snijder B, Regli L, Ravi VM, Heiland DH, Sentman CL, Weller M, Weiss T
Clin Cancer Res 2022 Nov 1;28(21):4747-4756. doi: 10.1158/1078-0432.CCR-21-4384. PMID: 36037304
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850
Encephalocraniocutaneous Lipomatosis.
Bavle A, Shah R, Gross N, Gavula T, Ruiz-Elizalde A, Wierenga K, McNall-Knapp R
J Pediatr Hematol Oncol 2018 Oct;40(7):553-554. doi: 10.1097/MPH.0000000000001170. PMID: 29683947

Diagnosis

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
An update on the central nervous system manifestations of neurofibromatosis type 1.
Nix JS, Blakeley J, Rodriguez FJ
Acta Neuropathol 2020 Apr;139(4):625-641. Epub 2019 Apr 8 doi: 10.1007/s00401-019-02002-2. PMID: 30963251Free PMC Article
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA
Nature 2019 Jan;565(7738):234-239. Epub 2018 Dec 19 doi: 10.1038/s41586-018-0792-9. PMID: 30568305Free PMC Article
Encephalocraniocutaneous Lipomatosis.
Bavle A, Shah R, Gross N, Gavula T, Ruiz-Elizalde A, Wierenga K, McNall-Knapp R
J Pediatr Hematol Oncol 2018 Oct;40(7):553-554. doi: 10.1097/MPH.0000000000001170. PMID: 29683947
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ Jr, Mehta MP
N Engl J Med 2014 Feb 20;370(8):699-708. doi: 10.1056/NEJMoa1308573. PMID: 24552317Free PMC Article

Therapy

Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA
Nature 2019 Jan;565(7738):234-239. Epub 2018 Dec 19 doi: 10.1038/s41586-018-0792-9. PMID: 30568305Free PMC Article
Encephalocraniocutaneous Lipomatosis.
Bavle A, Shah R, Gross N, Gavula T, Ruiz-Elizalde A, Wierenga K, McNall-Knapp R
J Pediatr Hematol Oncol 2018 Oct;40(7):553-554. doi: 10.1097/MPH.0000000000001170. PMID: 29683947
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ Jr, Mehta MP
N Engl J Med 2014 Feb 20;370(8):699-708. doi: 10.1056/NEJMoa1308573. PMID: 24552317Free PMC Article

Prognosis

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Identification of a single cell-based signature for predicting prognosis risk and immunotherapy response in patients with glioblastoma.
Dai Z, Zhang N, Zhou R, Zhang H, Zhang L, Wang Z, Zeng W, Luo P, Zhang J, Liu Z, Cheng Q
Clin Immunol 2023 Jun;251:109345. Epub 2023 Apr 24 doi: 10.1016/j.clim.2023.109345. PMID: 37100336
Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850
Glioblastoma: changing expectations?
Arribas Alpuente L, Menéndez López A, Yayá Tur R
Clin Transl Oncol 2011 Apr;13(4):240-8. doi: 10.1007/s12094-011-0648-3. PMID: 21493184

Clinical prediction guides

Identification of a single cell-based signature for predicting prognosis risk and immunotherapy response in patients with glioblastoma.
Dai Z, Zhang N, Zhou R, Zhang H, Zhang L, Wang Z, Zeng W, Luo P, Zhang J, Liu Z, Cheng Q
Clin Immunol 2023 Jun;251:109345. Epub 2023 Apr 24 doi: 10.1016/j.clim.2023.109345. PMID: 37100336
Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma.
Tong S, Xia M, Xu Y, Sun Q, Ye L, Yuan F, Wang Y, Cai J, Ye Z, Tian D
J Transl Med 2023 Feb 22;21(1):136. doi: 10.1186/s12967-023-03970-6. PMID: 36814293Free PMC Article
Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
Glioblastoma care in the elderly.
Jordan JT, Gerstner ER, Batchelor TT, Cahill DP, Plotkin SR
Cancer 2016 Jan 15;122(2):189-97. Epub 2015 Nov 30 doi: 10.1002/cncr.29742. PMID: 26618888
Childhood brain tumors.
Sklar CA
J Pediatr Endocrinol Metab 2002 May;15 Suppl 2:669-73. doi: 10.1515/jpem.2002.15.s2.669. PMID: 12092679

Recent systematic reviews

Association between Single Nucleotide Polymorphisms and Glioma Risk: A Systematic Literature Review.
Tavares CB, Gomes-Braga FDCSA, Sousa EB, Brito JNPO, Melo MA, Campelo V, Neto FM, de Araújo RML, Kessler IM, Sousa Júnior LM, Filho LCC, Aguiar YQ, Lopes Costa PV, da Silva BB
Cancer Invest 2020 Mar;38(3):169-183. Epub 2020 Mar 2 doi: 10.1080/07357907.2020.1719502. PMID: 31957502
A systematic review of outcome in intramedullary ependymoma and astrocytoma.
Hamilton KR, Lee SS, Urquhart JC, Jonker BP
J Clin Neurosci 2019 May;63:168-175. Epub 2019 Mar 2 doi: 10.1016/j.jocn.2019.02.001. PMID: 30833131
Anthropometrics at birth and risk of a primary central nervous system tumour: A systematic review and meta-analysis.
Georgakis MK, Kalogirou EI, Liaskas A, Karalexi MA, Papathoma P, Ladopoulou K, Kantzanou M, Tsivgoulis G; NARECHEM-BT Working Group, Petridou ET
Eur J Cancer 2017 Apr;75:117-131. Epub 2017 Feb 20 doi: 10.1016/j.ejca.2016.12.033. PMID: 28219020
Risk of Adverse Vascular Events in Newly Diagnosed Glioblastoma Multiforme Patients Treated with Bevacizumab: a Systematic Review and Meta-Analysis.
Li X, Huang R, Xu Z
Sci Rep 2015 Oct 1;5:14698. doi: 10.1038/srep14698. PMID: 26423913Free PMC Article
Temozolomide for high grade glioma.
Hart MG, Garside R, Rogers G, Stein K, Grant R
Cochrane Database Syst Rev 2013 Apr 30;2013(4):CD007415. doi: 10.1002/14651858.CD007415.pub2. PMID: 23633341Free PMC Article

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