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Metastatic malignant neoplasm in the eye

MedGen UID:
91115
•Concept ID:
C0347019
•
Neoplastic Process
Synonyms: Eye Metastasis; eye metastasis; Metastases to Eye; Metastases to eye; Metastases to the Eye; Metastases to the eye; Metastasis to eye; Metastasis to Eye; metastasis to eye; Metastasis to the Eye; metastasis to the eye; Metastatic Malignant Neoplasm in the Eye; metastatic malignant neoplasm in the eye; Metastatic malignant neoplasm of eye; Metastatic malignant neoplasm to eye; Metastatic Malignant Neoplasm to the Eye; Metastatic malignant neoplasm to the eye; Metastatic Neoplasm to the Eye; Metastatic neoplasm to the eye; Metastatic Tumor to the Eye; Metastatic tumor to the eye; Metastatic tumour to the eye; Secondary malignant neoplasm of eye
SNOMED CT: Metastasis to eye (94292003); Secondary malignant neoplasm of eye (94292003); Metastatic malignant neoplasm to eye (94292003); Metastatic malignant neoplasm of eye (94292003)
 
Monarch Initiative: MONDO:0044913

Definition

A malignant neoplasm that has spread to the eye from another anatomic site. [from NCI]

Professional guidelines

PubMed

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
Uveal melanoma: From diagnosis to treatment and the science in between.
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Recent clinical studies

Etiology

Epiretinal membrane: A review.
Fung AT, Galvin J, Tran T
Clin Exp Ophthalmol 2021 Apr;49(3):289-308. Epub 2021 Mar 24 doi: 10.1111/ceo.13914. PMID: 33656784
Thyroid and Eye: Where They Meet in Clinical Practice.
El-Eshmawy MM, Shahin M
Endocr Metab Immune Disord Drug Targets 2020;20(1):39-49. doi: 10.2174/1871530319666190618120107. PMID: 31237221
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Pathology of eyelid tumors.
Pe'er J
Indian J Ophthalmol 2016 Mar;64(3):177-90. doi: 10.4103/0301-4738.181752. PMID: 27146927Free PMC Article
Retinoblastoma: An update.
Delhiwala KS, Vadakkal IP, Mulay K, Khetan V, Wick MR
Semin Diagn Pathol 2016 May;33(3):133-40. Epub 2015 Oct 23 doi: 10.1053/j.semdp.2015.10.007. PMID: 26969537

Diagnosis

Thyroid and Eye: Where They Meet in Clinical Practice.
El-Eshmawy MM, Shahin M
Endocr Metab Immune Disord Drug Targets 2020;20(1):39-49. doi: 10.2174/1871530319666190618120107. PMID: 31237221
New concepts in the diagnosis and management of choroidal metastases.
Mathis T, Jardel P, Loria O, Delaunay B, Nguyen AM, Lanza F, Mosci C, Caujolle JP, Kodjikian L, Thariat J
Prog Retin Eye Res 2019 Jan;68:144-176. Epub 2018 Sep 19 doi: 10.1016/j.preteyeres.2018.09.003. PMID: 30240895
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Ophthalmic manifestations of leukemia.
Talcott KE, Garg RJ, Garg SJ
Curr Opin Ophthalmol 2016 Nov;27(6):545-551. doi: 10.1097/ICU.0000000000000309. PMID: 27585213
Ocular neoplastic disease.
Mahajan A, Crum A, Johnson MH, Materin MA
Semin Ultrasound CT MR 2011 Feb;32(1):28-37. doi: 10.1053/j.sult.2010.12.001. PMID: 21277489

Therapy

Artificial Intelligence-Assisted Colonoscopy for Colorectal Cancer Screening: A Multicenter Randomized Controlled Trial.
Xu H, Tang RSY, Lam TYT, Zhao G, Lau JYW, Liu Y, Wu Q, Rong L, Xu W, Li X, Wong SH, Cai S, Wang J, Liu G, Ma T, Liang X, Mak JWY, Xu H, Yuan P, Cao T, Li F, Ye Z, Shutian Z, Sung JJY
Clin Gastroenterol Hepatol 2023 Feb;21(2):337-346.e3. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.07.006. PMID: 35863686
Metastatic uveal melanoma: The final frontier.
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Thyroid and Eye: Where They Meet in Clinical Practice.
El-Eshmawy MM, Shahin M
Endocr Metab Immune Disord Drug Targets 2020;20(1):39-49. doi: 10.2174/1871530319666190618120107. PMID: 31237221
Ophthalmic manifestations of leukemia.
Talcott KE, Garg RJ, Garg SJ
Curr Opin Ophthalmol 2016 Nov;27(6):545-551. doi: 10.1097/ICU.0000000000000309. PMID: 27585213
Ocular metastases.
Cohen VM
Eye (Lond) 2013 Feb;27(2):137-41. Epub 2012 Dec 7 doi: 10.1038/eye.2012.252. PMID: 23222564Free PMC Article

Prognosis

Secondary ocular malignancies: A review.
Yeung AM, Wells JR, Grossniklaus HE
Clin Exp Ophthalmol 2021 Mar;49(2):161-168. Epub 2021 Jan 10 doi: 10.1111/ceo.13889. PMID: 33426794
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Uveal melanoma: estimating prognosis.
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article
Understanding intraocular lymphomas.
Coupland SE, Damato B
Clin Exp Ophthalmol 2008 Aug;36(6):564-78. doi: 10.1111/j.1442-9071.2008.01843.x. PMID: 18954321
Intraocular lymphoma.
Chan CC, Buggage RR, Nussenblatt RB
Curr Opin Ophthalmol 2002 Dec;13(6):411-8. doi: 10.1097/00055735-200212000-00012. PMID: 12441846

Clinical prediction guides

Metastatic uveal melanoma: The final frontier.
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Epiretinal membrane: A review.
Fung AT, Galvin J, Tran T
Clin Exp Ophthalmol 2021 Apr;49(3):289-308. Epub 2021 Mar 24 doi: 10.1111/ceo.13914. PMID: 33656784
Cancers of the eye.
Maheshwari A, Finger PT
Cancer Metastasis Rev 2018 Dec;37(4):677-690. doi: 10.1007/s10555-018-9762-9. PMID: 30203109
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.
Puram SV, Tirosh I, Parikh AS, Patel AP, Yizhak K, Gillespie S, Rodman C, Luo CL, Mroz EA, Emerick KS, Deschler DG, Varvares MA, Mylvaganam R, Rozenblatt-Rosen O, Rocco JW, Faquin WC, Lin DT, Regev A, Bernstein BE
Cell 2017 Dec 14;171(7):1611-1624.e24. Epub 2017 Nov 30 doi: 10.1016/j.cell.2017.10.044. PMID: 29198524Free PMC Article
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Recent systematic reviews

Clinical Characteristics Associated With Secondary Generalization in Patients With Ocular Myasthenia Gravis: A Systematic Review and Meta-analysis.
Fang CEH, Bokre D, Wong SH
Neurology 2023 Oct 17;101(16):e1594-e1605. Epub 2023 Aug 29 doi: 10.1212/WNL.0000000000207642. PMID: 37643888Free PMC Article
Efficacy of immune checkpoint inhibition in metastatic uveal melanoma: a systematic review and meta-analysis.
Pham JP, On L, Ardolino L, Hurwitz J, Salaun H, Sim HW, Joshua AM
Melanoma Res 2023 Aug 1;33(4):316-325. Epub 2023 May 18 doi: 10.1097/CMR.0000000000000900. PMID: 37199712
Vitreoretinal Surgery in the Prevention and Treatment of Toxic Tumour Syndrome in Uveal Melanoma: A Systematic Review.
Romano MR, Catania F, Confalonieri F, Zollet P, Allegrini D, Sergenti J, Lanza FB, Ferrara M, Angi M
Int J Mol Sci 2021 Sep 17;22(18) doi: 10.3390/ijms221810066. PMID: 34576231Free PMC Article
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
Cutaneous malignant melanoma metastatic to the eye, lids, and orbit.
Rosenberg C, Finger PT
Surv Ophthalmol 2008 May-Jun;53(3):187-202. doi: 10.1016/j.survophthal.2008.02.003. PMID: 18501266

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