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Nonorganic insomnia

MedGen UID:
91143
•Concept ID:
C0349255
•
Disease or Syndrome
Synonyms: Insomnia, Nonorganic; Nonorganic Insomnia
SNOMED CT: Nonorganic insomnia (192454004)

Definition

Insomnia as a result of an extrinsic cause. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNonorganic insomnia

Professional guidelines

PubMed

The key-lock principle in the diagnosis and treatment of nonorganic insomnia related to psychiatric disorders: sleep laboratory investigations.
Saletu-Zyhlarz GM, Arnold O, Saletu B, Anderer P
Methods Find Exp Clin Pharmacol 2002;24 Suppl D:37-49. PMID: 12575467

Recent clinical studies

Etiology

Gender differences in outpatients with dementia from a large psychiatric hospital in China.
Zhou J, Guo C, Ren L, Zhu D, Zhen W, Zhang S, Zhang Q
BMC Psychiatry 2022 Mar 21;22(1):208. doi: 10.1186/s12888-022-03852-z. PMID: 35313835Free PMC Article
Insomnia in female nurses: a nationwide retrospective study.
Tsai K, Lee TY, Chung MH
Int J Occup Saf Ergon 2017 Mar;23(1):127-132. Epub 2016 Nov 16 doi: 10.1080/10803548.2016.1248604. PMID: 27846774
Sleep in young adults with Asperger syndrome.
Tani P, Lindberg N, Nieminen-von Wendt T, von Wendt L, Virkkala J, Appelberg B, Porkka-Heiskanen T
Neuropsychobiology 2004;50(2):147-52. doi: 10.1159/000079106. PMID: 15292669
Placebo-controlled sleep laboratory studies on the acute effects of zolpidem on objective and subjective sleep and awakening quality in nonorganic insomnia related to neurotic and stress-related disorder.
Saletu-Zyhlarz G, Anderer P, Brandstätter N, Dantendorfer K, Gruber G, Mandl M, Ritter K, Zoghlami A, Saletu B
Neuropsychobiology 2000;41(3):139-48. doi: 10.1159/000026646. PMID: 10754428
Nonorganic insomnia in generalized anxiety disorder. 1. Controlled studies on sleep, awakening and daytime vigilance utilizing polysomnography and EEG mapping.
Saletu-Zyhlarz G, Saletu B, Anderer P, Brandstätter N, Frey R, Gruber G, Klösch G, Mandl M, Grünberger J, Linzmayer L
Neuropsychobiology 1997;36(3):117-29. doi: 10.1159/000119373. PMID: 9313244

Diagnosis

The diagnostic validity of the Athens Insomnia Scale.
Soldatos CR, Dikeos DG, Paparrigopoulos TJ
J Psychosom Res 2003 Sep;55(3):263-7. doi: 10.1016/s0022-3999(02)00604-9. PMID: 12932801
Quality of life in nonorganic and organic sleep disorders: II. Correlation with objective and subjective quality of sleep and awakening.
Prause W, Saletu B, Anderer P, Gruber G, Löffler-Stastka H, Klösch G, Mandl M, Grätzhofer E, Saletu-Zyhlarz G, Katschnig H
Wien Klin Wochenschr 2003 May 30;115(10):326-33. doi: 10.1007/BF03041484. PMID: 12800446
The key-lock principle in the diagnosis and treatment of nonorganic insomnia related to psychiatric disorders: sleep laboratory investigations.
Saletu-Zyhlarz GM, Arnold O, Saletu B, Anderer P
Methods Find Exp Clin Pharmacol 2002;24 Suppl D:37-49. PMID: 12575467
Placebo-controlled sleep laboratory studies on the acute effects of zolpidem on objective and subjective sleep and awakening quality in nonorganic insomnia related to neurotic and stress-related disorder.
Saletu-Zyhlarz G, Anderer P, Brandstätter N, Dantendorfer K, Gruber G, Mandl M, Ritter K, Zoghlami A, Saletu B
Neuropsychobiology 2000;41(3):139-48. doi: 10.1159/000026646. PMID: 10754428
Nonorganic insomnia in generalized anxiety disorder. 1. Controlled studies on sleep, awakening and daytime vigilance utilizing polysomnography and EEG mapping.
Saletu-Zyhlarz G, Saletu B, Anderer P, Brandstätter N, Frey R, Gruber G, Klösch G, Mandl M, Grünberger J, Linzmayer L
Neuropsychobiology 1997;36(3):117-29. doi: 10.1159/000119373. PMID: 9313244

Therapy

Insomnia in somatoform pain disorder: sleep laboratory studies on differences to controls and acute effects of trazodone, evaluated by the Somnolyzer 24 x 7 and the Siesta database.
Saletu B, Prause W, Anderer P, Mandl M, Aigner M, Mikova O, Saletu-Zyhlarz GM
Neuropsychobiology 2005;51(3):148-63. Epub 2005 Apr 18 doi: 10.1159/000085207. PMID: 15838186
Sleep in young adults with Asperger syndrome.
Tani P, Lindberg N, Nieminen-von Wendt T, von Wendt L, Virkkala J, Appelberg B, Porkka-Heiskanen T
Neuropsychobiology 2004;50(2):147-52. doi: 10.1159/000079106. PMID: 15292669
Insomnia in depression: differences in objective and subjective sleep and awakening quality to normal controls and acute effects of trazodone.
Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, Gruber G, Mandl M, Strobl R, Gollner D, Prause W, Saletu B
Prog Neuropsychopharmacol Biol Psychiatry 2002 Feb;26(2):249-60. doi: 10.1016/s0278-5846(01)00262-7. PMID: 11817501
Insomnia related to dysthymia: polysomnographic and psychometric comparison with normal controls and acute therapeutic trials with trazodone.
Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, Semler B, Decker K, Parapatics S, Tschida U, Winkler A, Saletu B
Neuropsychobiology 2001;44(3):139-49. doi: 10.1159/000054934. PMID: 11586054
Placebo-controlled sleep laboratory studies on the acute effects of zolpidem on objective and subjective sleep and awakening quality in nonorganic insomnia related to neurotic and stress-related disorder.
Saletu-Zyhlarz G, Anderer P, Brandstätter N, Dantendorfer K, Gruber G, Mandl M, Ritter K, Zoghlami A, Saletu B
Neuropsychobiology 2000;41(3):139-48. doi: 10.1159/000026646. PMID: 10754428

Prognosis

Insomnia in female nurses: a nationwide retrospective study.
Tsai K, Lee TY, Chung MH
Int J Occup Saf Ergon 2017 Mar;23(1):127-132. Epub 2016 Nov 16 doi: 10.1080/10803548.2016.1248604. PMID: 27846774
The diagnostic validity of the Athens Insomnia Scale.
Soldatos CR, Dikeos DG, Paparrigopoulos TJ
J Psychosom Res 2003 Sep;55(3):263-7. doi: 10.1016/s0022-3999(02)00604-9. PMID: 12932801
Quality of life in nonorganic and organic sleep disorders: I. Comparison with normative data.
Saletu B, Prause W, Löffler-Stastka H, Anderer P, Brandstätter N, Zoghlami A, Saletu-Zyhlarz G, Katschnig H
Wien Klin Wochenschr 2003 Apr 30;115(7-8):246-54. doi: 10.1007/BF03040323. PMID: 12778777

Clinical prediction guides

Gender differences in outpatients with dementia from a large psychiatric hospital in China.
Zhou J, Guo C, Ren L, Zhu D, Zhen W, Zhang S, Zhang Q
BMC Psychiatry 2022 Mar 21;22(1):208. doi: 10.1186/s12888-022-03852-z. PMID: 35313835Free PMC Article
Insomnia in depression: differences in objective and subjective sleep and awakening quality to normal controls and acute effects of trazodone.
Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, Gruber G, Mandl M, Strobl R, Gollner D, Prause W, Saletu B
Prog Neuropsychopharmacol Biol Psychiatry 2002 Feb;26(2):249-60. doi: 10.1016/s0278-5846(01)00262-7. PMID: 11817501
Insomnia related to dysthymia: polysomnographic and psychometric comparison with normal controls and acute therapeutic trials with trazodone.
Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, Semler B, Decker K, Parapatics S, Tschida U, Winkler A, Saletu B
Neuropsychobiology 2001;44(3):139-49. doi: 10.1159/000054934. PMID: 11586054
Nonorganic insomnia in generalized anxiety disorder. 2. Comparative studies on sleep, awakening, daytime vigilance and anxiety under lorazepam plus diphenhydramine (Somnium) versus lorazepam alone, utilizing clinical, polysomnographic and EEG mapping methods.
Saletu B, Saletu-Zyhlarz G, Anderer P, Brandstätter N, Frey R, Gruber G, Klösch G, Mandl M, Grünberger J, Linzmayer L
Neuropsychobiology 1997;36(3):130-52. doi: 10.1159/000119374. PMID: 9313245
Nonorganic insomnia in generalized anxiety disorder. 1. Controlled studies on sleep, awakening and daytime vigilance utilizing polysomnography and EEG mapping.
Saletu-Zyhlarz G, Saletu B, Anderer P, Brandstätter N, Frey R, Gruber G, Klösch G, Mandl M, Grünberger J, Linzmayer L
Neuropsychobiology 1997;36(3):117-29. doi: 10.1159/000119373. PMID: 9313244

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