Entry - 133600 - EXOSTOSES OF HEEL - OMIM

 
 
133600

EXOSTOSES OF HEEL


Clinical Synopsis
 

Limbs
- Exostosis of heel
Inheritance
- Autosomal dominant
▲ Close

▼ TEXT

Gould (1942) described the condition in grandfather, father and son, i.e., males of 3 generations. X-rays were not described. Exostosis of the heel, possibly of the same type, is a manifestation of the Reiter syndrome, a rheumatic disorder that shows a high order of association with a specific HLA type (142800), namely B27 (Brewerton et al., 1973; McClusky et al., 1984; Woodrow et al., 1974). Thus might familial aggregation be accounted for.


▼ REFERENCES

  1. Brewerton, D. A., Nicholls, A., Oates, J. K., Caffrey, M., Walters, D., James, D. C. O. Reiter's disease and HL-A 27. Lancet 302: 996-998, 1973. Note: Originally Volume II. [PubMed: 4127280, related citations] [Full Text]

  2. Gould, E. A. Three generations of exostoses of the heel. Inherited from father to son. J. Hered. 33: 228 only, 1942.

  3. McClusky, O. E., Lordon, R. E., Arnett, F. C. HL-A 27 in Reiter's syndrome and psoriatic arthritis: a genetic factor in disease susceptibility and expression. J. Rheum. 11: 571 only, 1984. [PubMed: 6334736, related citations]

  4. Woodrow, J. C., Treanor, B., Usher, N. The HL-A system in Reiter's syndrome. Tissue Antigens 4: 533-540, 1974.


Creation Date:
Victor A. McKusick : 6/4/1986
Edit History:
alopez : 11/09/2018
terry : 01/14/2009
mimadm : 9/24/1994
carol : 1/24/1994
carol : 3/31/1992
supermim : 3/16/1992
carol : 3/4/1992
supermim : 3/20/1990

133600

EXOSTOSES OF HEEL



TEXT

Gould (1942) described the condition in grandfather, father and son, i.e., males of 3 generations. X-rays were not described. Exostosis of the heel, possibly of the same type, is a manifestation of the Reiter syndrome, a rheumatic disorder that shows a high order of association with a specific HLA type (142800), namely B27 (Brewerton et al., 1973; McClusky et al., 1984; Woodrow et al., 1974). Thus might familial aggregation be accounted for.


REFERENCES

  1. Brewerton, D. A., Nicholls, A., Oates, J. K., Caffrey, M., Walters, D., James, D. C. O. Reiter's disease and HL-A 27. Lancet 302: 996-998, 1973. Note: Originally Volume II. [PubMed: 4127280] [Full Text: https://doi.org/10.1016/s0140-6736(73)91091-x]

  2. Gould, E. A. Three generations of exostoses of the heel. Inherited from father to son. J. Hered. 33: 228 only, 1942.

  3. McClusky, O. E., Lordon, R. E., Arnett, F. C. HL-A 27 in Reiter's syndrome and psoriatic arthritis: a genetic factor in disease susceptibility and expression. J. Rheum. 11: 571 only, 1984. [PubMed: 6334736]

  4. Woodrow, J. C., Treanor, B., Usher, N. The HL-A system in Reiter's syndrome. Tissue Antigens 4: 533-540, 1974.


Creation Date:
Victor A. McKusick : 6/4/1986

Edit History:
alopez : 11/09/2018
terry : 01/14/2009
mimadm : 9/24/1994
carol : 1/24/1994
carol : 3/31/1992
supermim : 3/16/1992
carol : 3/4/1992
supermim : 3/20/1990



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 22, 2024