cfim-1 Cleavage and polyadenylation specificity factor subunit 5 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: cfim-1
Gene description: Cleavage and polyadenylation specificity factor subunit 5
Primary source: WormBase:WBGene00009668
Locus tag: CELE_F43G9.5
See related: AllianceGenome:WB:WBGene00009668
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables identical protein binding activity. Predicted to be involved in mRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of mRNA cleavage factor complex. Is expressed in body wall musculature; hypodermis; intestine; and pharynx. Orthologous to human NUDT21 (nudix hydrolase 21). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:: chromosome: I

Exon count:: 4

Sequence:: Chromosome: I; NC_003279.8 (8615388..8616420)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F43G9.5 (e-PCR)
- UniSTS:315769

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables mRNA 3'-UTR AU-rich region binding	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of mRNA cleavage factor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mRNA cleavage factor complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Cleavage and polyadenylation specificity factor subunit 5

NP_492334.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8615388..8616420

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059933.4 → NP_492334.1 Cleavage and polyadenylation specificity factor subunit 5 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492334.1

Status: REVIEWED

UniProtKB/TrEMBL

Q93716

Conserved Domains (1) summary

pfam13869
Location:32 → 219

NUDIX_2; Nucleotide hydrolase