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rpl-22 Large ribosomal subunit protein eL22 [ Caenorhabditis elegans ]

Gene ID: 173873, updated on 23-Nov-2023

Summary

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Gene symbol
rpl-22
Gene description
Large ribosomal subunit protein eL22
Primary source
WormBase:WBGene00004434
Locus tag
CELE_C27A2.2
See related
AllianceGenome:WB:WBGene00004434
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Orthologous to several human genes including RPL22 (ribosomal protein L22). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (5055616..5056214)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene ncRNA Neighboring gene Securin-like protein Neighboring gene Histidine acid phosphatase Neighboring gene ncRNA Neighboring gene tRNA-Ile Neighboring gene Lysosomal acid phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges. Rehain-Bell K, et al. Curr Biol, 2017 Mar 20. PMID 28285996, Free PMC Article
  2. Genetic interaction with temperature is an important determinant of nematode longevity. Miller H, et al. Aging Cell, 2017 Dec. PMID 28940623, Free PMC Article
  3. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
  4. The nascent polypeptide-associated complex is a key regulator of proteostasis. Kirstein-Miles J, et al. EMBO J, 2013 May 15. PMID 23604074, Free PMC Article
  5. Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes. Arnold A, et al. Nucleic Acids Res, 2014 Dec 1. PMID 25378320, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Large ribosomal subunit protein eL22
NP_494932.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5055616..5056214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062531.8 → NP_494932.1  Large ribosomal subunit protein eL22 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_494932.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P52819, P85027
    Conserved Domains (1) summary
    pfam01776
    Location:18 → 124
    Ribosomal_L22e; Ribosomal L22e protein family

RNA

  1. NR_132580.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P52819.3

Gene LinkOut

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