U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rps-3 Small ribosomal subunit protein uS3 [ Caenorhabditis elegans ]

Gene ID: 175879, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
rps-3
Gene description
Small ribosomal subunit protein uS3
Primary source
WormBase:WBGene00004472
Locus tag
CELE_C23G10.3
See related
AllianceGenome:WB:WBGene00004472
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of apoptotic signaling pathway. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in nucleus. Orthologous to human RPS3 (ribosomal protein S3). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (6206803..6207965)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene 26S proteasome non-ATPase regulatory subunit 1 Neighboring gene NADAR domain-containing protein Neighboring gene RutC family protein C23G10.2 Neighboring gene Serine/threonine-protein phosphatase C23G10.1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Caenorhabditis elegans evolves a new architecture for the multi-aminoacyl-tRNA synthetase complex. Havrylenko S, et al. J Biol Chem, 2011 Aug 12. PMID 21685384, Free PMC Article
  2. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
  3. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
  4. The nascent polypeptide-associated complex is a key regulator of proteostasis. Kirstein-Miles J, et al. EMBO J, 2013 May 15. PMID 23604074, Free PMC Article
  5. A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans. Updike DL, et al. Genetics, 2009 Dec. PMID 19805813, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosolic ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Small ribosomal subunit protein uS3
NP_498349.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6206803..6207965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065948.6 → NP_498349.1  Small ribosomal subunit protein uS3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498349.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48152
    Conserved Domains (3) summary
    cd02413
    Location:17 → 97
    40S_S3_KH; K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3 is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH ...
    PTZ00084
    Location:5 → 218
    PTZ00084; 40S ribosomal protein S3; Provisional
    pfam00189
    Location:107 → 188
    Ribosomal_S3_C; Ribosomal protein S3, C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48152.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous