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lsm-7 Sm domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177988, updated on 11-Apr-2024

Summary

Gene symbol
lsm-7
Gene description
Sm domain-containing protein
Primary source
WormBase:WBGene00003081
Locus tag
CELE_ZK593.7
See related
AllianceGenome:WB:WBGene00003081
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in nucleus. Predicted to be part of Lsm1-7-Pat1 complex; spliceosomal complex; and spliceosomal snRNP complex. Orthologous to human LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See lsm-7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (10933502..10934189)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Lysine-specific demethylase rbr-2;[histone H3]-trimethyl-L-lysine(4) demethylase Neighboring gene Dynactin subunit 1;Dynein associated protein domain-containing protein Neighboring gene Protein lgg;Protein lgg-2 Neighboring gene Protein adenylyltransferase fic-1

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
contributes_to RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular organelle IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Sm domain-containing protein
NP_502034.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10933502..10934189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069633.6NP_502034.1  Sm domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502034.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23543
    Conserved Domains (1) summary
    cd01729
    Location:1098
    LSm7; Like-Sm protein 7