ugt-22 UDP-glucuronosyltransferase [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Gene symbol: ugt-22
Gene description: UDP-glucuronosyltransferase
Primary source: WormBase:WBGene00007455
Locus tag: CELE_C08F11.8
See related: AllianceGenome:WB:WBGene00007455
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Apr 2022]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

Location:: chromosome: IV

Exon count:: 10

Sequence:: Chromosome: IV; NC_003282.8 (13639260..13644402)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

C08F11.7 (e-PCR)
- UniSTS:305569

C08F11.8 (e-PCR)
- UniSTS:313512

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables UDP-glycosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glucuronosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: UDP-glucuronosyltransferase

NP_502633.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

13639260..13644402

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070232.6 → NP_502633.1 UDP-glucuronosyltransferase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_502633.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9U3Q6

Conserved Domains (2) summary

PHA03392
Location:256 → 515

egt; ecdysteroid UDP-glucosyltransferase; Provisional

pfam00201
Location:36 → 530

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase