PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 [Bos taurus (cattle)] - Gene

Summary

Gene symbol: PIK3R3
Gene description: phosphoinositide-3-kinase regulatory subunit 3
See related: BGD:BT12001; Ensembl:ENSBTAG00000002979
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: p55PIK
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (99963094..100067354)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BMS2891 (e-PCR), detects polymorphism
- UniSTS:19008

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in insulin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phosphatidylinositol phosphate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of phosphatidylinositol 3-kinase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphatidylinositol 3-kinase regulatory subunit gamma

Names: PI3-kinase p85 subunit gamma; PI3-kinase regulatory subunit gamma; PI3-kinase subunit p85-gamma; PI3K regulatory subunit gamma; phosphatidylinositol 3-kinase 85 kDa regulatory subunit gamma; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma); phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); ptdIns-3-kinase p85-gamma; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p85-gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174796.1 → NP_777221.1 phosphatidylinositol 3-kinase regulatory subunit gamma

See identical proteins and their annotated locations for NP_777221.1

Status: PROVISIONAL

Source sequence(s)

AF036256

UniProtKB/Swiss-Prot

O46404

Related

ENSBTAP00000003878.5, ENSBTAT00000003878.7

Conserved Domains (4) summary

cd09930
Location:351 → 454

SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85

cd09942
Location:59 → 167

SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85

pfam16454
Location:171 → 330

PI3K_P85_iSH2; Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

cl23765
Location:172 → 332

iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

Range

99963094..100067354

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024985027.2 → XP_024840795.1 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

Conserved Domains (3) summary

cd09930
Location:307 → 410

SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85

cd09942
Location:15 → 123

SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85

cl25402
Location:128 → 288

iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits