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ets2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 [ Danio rerio (zebrafish) ]

Gene ID: 326672, updated on 11-Apr-2024

Summary

Official Symbol
ets2provided by ZNC
Official Full Name
v-ets avian erythroblastosis virus E26 oncogene homolog 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-552
See related
Ensembl:ENSDARG00000103980 AllianceGenome:ZFIN:ZDB-GENE-050522-552
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92106; wu:fe02h08; wu:fk74c05
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in endothelial cell; head; lateral plate mesoderm; and margin. Orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 10
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (187809..196598)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (187745..196815)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene potassium inwardly rectifying channel subfamily J member 6 Neighboring gene potassium inwardly rectifying channel subfamily J member 15 Neighboring gene ETS transcription factor ERG Neighboring gene proteasome (prosome, macropain) assembly chaperone 1 Neighboring gene myelin protein zero-like 1 like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein C-ets-2
Names
avian leukemia oncogene 2
v-ets erythroblastosis virus E26 oncogene homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001023580.1NP_001018874.1  protein C-ets-2

    See identical proteins and their annotated locations for NP_001018874.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095899
    UniProtKB/TrEMBL
    A0A8M1N6I5, Q501S1
    Related
    ENSDARP00000131539.1, ENSDART00000161007.1
    Conserved Domains (2) summary
    smart00413
    Location:332416
    ETS; erythroblast transformation specific domain
    cl15755
    Location:76164
    SAM_superfamily; SAM (Sterile alpha motif )

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    187809..196598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)