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ITGA3 integrin subunit alpha 3 [ Gallus gallus (chicken) ]

Gene ID: 373946, updated on 3-Apr-2024

Summary

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Symbol
ITGA3provided by CGNC
Full Name
integrin subunit alpha 3provided by CGNC
Primary source
CGNC:48970
See related
Ensembl:ENSGALG00010025286
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
27
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (2795467..2811354, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (3909352..3943594, complement)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain containing 14 Neighboring gene pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 2, mitochondrial Neighboring gene distal-less homeobox 3 Neighboring gene distal-less homeobox 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional comparison of the alpha3A and alpha3B cytoplasmic domain variants of the chicken alpha3 integrin subunit. DiPersio CM, et al. Exp Cell Res, 2001 Aug 1. PMID 11461117

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-3
Names
integrin alpha 3B subunit cytoplasmic domain
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001389288.2 → NP_001376217.2  integrin alpha-3 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000364
    UniProtKB/TrEMBL
    A0A8V1A4I5
    Related
    ENSGALP00010038106.1, ENSGALT00010061727.1

  2. NM_204146.3 → NP_989477.3  integrin alpha-3 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000364
    UniProtKB/TrEMBL
    A0A8V1A6W7
    Related
    ENSGALP00010038110.1, ENSGALT00010061739.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2795467..2811354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040653053.2 → XP_040508987.1  integrin alpha-3 isoform X2

    UniProtKB/TrEMBL
    Q98TT7
    Conserved Domains (1) summary
    smart00191
    Location:348 → 400
    Int_alpha; Integrin alpha (beta-propellor repeats)

  2. XM_040653052.2 → XP_040508986.1  integrin alpha-3 isoform X1

    UniProtKB/TrEMBL
    Q98TT7
    Conserved Domains (1) summary
    smart00191
    Location:350 → 402
    Int_alpha; Integrin alpha (beta-propellor repeats)

  3. XM_040653055.2 → XP_040508989.1  integrin alpha-3 isoform X4

    UniProtKB/TrEMBL
    Q98TT7
    Conserved Domains (1) summary
    smart00191
    Location:206 → 258
    Int_alpha; Integrin alpha (beta-propellor repeats)

  4. XM_040653054.2 → XP_040508988.1  integrin alpha-3 isoform X3

    UniProtKB/TrEMBL
    Q98TT7
    Conserved Domains (1) summary
    smart00191
    Location:350 → 402
    Int_alpha; Integrin alpha (beta-propellor repeats)

RNA

  1. XR_005841928.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3909352..3943594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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