FOS Fos proto-oncogene, AP-1 transcription factor subunit [Gallus gallus (chicken)] - Gene

Summary

Symbol: FOSprovided by CGNC
Full Name: Fos proto-oncogene, AP-1 transcription factor subunitprovided by CGNC
Primary source: CGNC:49845
See related: Ensembl:ENSGALG00010006212
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	5	NC_052536.1 (37729411..37732328)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	5	NC_052577.1 (37699128..37702038)

Chromosome 5 - NC_052536.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The effect of monocular occlusion on hippocampal c-Fos expression in domestic chicks (Gallus gallus).
Title: The effect of monocular occlusion on hippocampal c-Fos expression in domestic chicks (Gallus gallus).
Inhibition of histone deacetylases in the chick brain up-regulates the expression of c-Fos and ZENK transcription factors and facilitates establishment of long-term memory.
Title: [Inhibition of histone deacetylases in the chick brain modulates expression of c-Fos and ZENK transcription factors and facilitates establishment of long-term memory].
Dimeric combinations of MafB, cFos and cJun in developing chick limb buds control the number of apoptotic cells.
Title: Dimeric combinations of MafB, cFos and cJun control the apoptosis-survival balance in limb morphogenesis.
This study demonistereated that c-fos gene expression accompanying filial imprinting in the newly hatched chick brain.
Title: Bioluminescence imaging of c-fos gene expression accompanying filial imprinting in the newly hatched chick brain.
results suggest that the learning-related increase in Fos protein production, which occurs in identifiable neuronal sub-populations in the intermediate and medial mesopallium, reflects events that make an early contribution to learning and/or memory
Title: Rapid induction of the immediate early gene c-fos in a chick forebrain system involved in memory.
The expression of c-fos in the optokinetic nuclei is linked to near peak firing rates and the novelty and duration of the visual signals, supporting the assumption that expression is related to stimulus contexts leading to neuronal plastic changes.
Title: Novel, continuous visual motion induces c-fos expression in the avian optokinetic nuclei and optic tectum.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein c-Fos

Names: FBJ murine osteosarcoma viral oncogene homolog; c-fos proto-oncogene; cellular oncogene fos; proto-oncogene c-Fos; proto-oncogene protein c-fos; transcription factor AP-1 subunit c-Fos; v-fos FBJ murine osteosarcoma viral oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205508.1 → NP_990839.1 protein c-Fos

See identical proteins and their annotated locations for NP_990839.1

Status: VALIDATED

Source sequence(s)

M37000

UniProtKB/Swiss-Prot

P11939

Related

ENSGALP00010008720.1, ENSGALT00010014790.1

Conserved Domains (1) summary

cd14721
Location:146 → 199

bZIP_Fos; Basic leucine zipper (bZIP) domain of the oncogene Fos (Fos): a DNA-binding and dimerization domain