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IL5 interleukin 5 [ Canis lupus familiaris (dog) ]

Gene ID: 403790, updated on 5-Mar-2024

Summary

Official Symbol
IL5provided by VGNC
Official Full Name
interleukin 5provided by VGNC
Primary source
VGNC:VGNC:41990
See related
Ensembl:ENSCAFG00845010566
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (21611416..21613216, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (19627141..19628942, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (20819966..20821765, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (20329893..20331692, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (20177516..20179316, complement)

Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098019 Neighboring gene solute carrier family 22 member 5 Neighboring gene RAD50 double strand break repair protein Neighboring gene interferon regulatory factor 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables interleukin-5 receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
interleukin-5
Names
IL-5
T-cell replacing factor
TRF
eosinophil differentiation factor
interleukin 5 (colony-stimulating factor, eosinophil)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006950.1NP_001006951.1  interleukin-5 precursor

    See identical proteins and their annotated locations for NP_001006951.1

    Status: PROVISIONAL

    Source sequence(s)
    AF331919
    UniProtKB/Swiss-Prot
    Q95J76
    UniProtKB/TrEMBL
    A0A8C0KMU0, A0A8C0QJQ5, A0A8I3NFI1
    Related
    ENSCAFP00845014535.1, ENSCAFT00845018628.1
    Conserved Domains (1) summary
    pfam02025
    Location:22133
    IL5; Interleukin 5

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051815.1 Reference ROS_Cfam_1.0

    Range
    21611416..21613216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049271.1 Alternate UMICH_Zoey_3.1

    Range
    20329893..20331692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

    Range
    20177516..20179316 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

    Range
    20819966..20821765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    19627141..19628942 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)