MAPKAPK3 MAPK activated protein kinase 3 [Gallus gallus (chicken)] - Gene

Summary

Symbol: MAPKAPK3provided by CGNC
Full Name: MAPK activated protein kinase 3provided by CGNC
Primary source: CGNC:1627
See related: Ensembl:ENSGALG00010028146
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	12	NC_052543.1 (1946874..1988947)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	12	NC_052584.1 (1984694..2026760)

Chromosome 12 - NC_052543.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium-dependent protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables calmodulin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calmodulin-dependent protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables mitogen-activated protein kinase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autophosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to cytokine	IEA Inferred from Electronic Annotation more info	PubMed
involved_in toll-like receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: MAP kinase-activated protein kinase 3

Names: mitogen-activated protein kinase-activated protein kinase 3

NP_001308487.1

EC 2.7.11.1

XP_025010225.1

EC 2.7.11.1

XP_025010226.1

EC 2.7.11.1

XP_040502114.1

EC 2.7.11.1

XP_046782163.1

EC 2.7.11.1

XP_046782164.1

EC 2.7.11.1

XP_046782165.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001321558.2 → NP_001308487.1 MAP kinase-activated protein kinase 3

Status: VALIDATED

Source sequence(s)

JAENSK010000251

UniProtKB/TrEMBL

A0A8V1ACK0, E1BT35

Related

ENSGALP00010041943.1, ENSGALT00010068200.1

Conserved Domains (1) summary

cd14172
Location:41 → 307

STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1946874..1988947

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025154458.3 → XP_025010226.1 MAP kinase-activated protein kinase 3 isoform X1

UniProtKB/TrEMBL

A0A3Q2U1E9

Conserved Domains (1) summary

cd14172
Location:41 → 307

STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3
XM_040646180.2 → XP_040502114.1 MAP kinase-activated protein kinase 3 isoform X2

UniProtKB/TrEMBL

A0A8V1ACK0, E1BT35

Conserved Domains (1) summary

cd14172
Location:41 → 307

STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3
XM_025154457.3 → XP_025010225.1 MAP kinase-activated protein kinase 3 isoform X1

UniProtKB/TrEMBL

A0A3Q2U1E9

Related

ENSGALP00010041941.1, ENSGALT00010068198.1

Conserved Domains (1) summary

cd14172
Location:41 → 307

STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

1984694..2026760

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046926208.1 → XP_046782164.1 MAP kinase-activated protein kinase 3 isoform X1
XM_046926209.1 → XP_046782165.1 MAP kinase-activated protein kinase 3 isoform X2
XM_046926207.1 → XP_046782163.1 MAP kinase-activated protein kinase 3 isoform X1