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LRP6 LDL receptor related protein 6 [ Gallus gallus (chicken) ]

Gene ID: 419097, updated on 5-Mar-2024

Summary

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Symbol
LRP6provided by CGNC
Full Name
LDL receptor related protein 6provided by CGNC
Primary source
CGNC:8784
See related
Ensembl:ENSGALG00010021562
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (71734320..71864350, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (72047002..72175917, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene microRNA 1727-1 Neighboring gene ETS variant 6 Neighboring gene BCL2 like 14 Neighboring gene uncharacterized LOC101751329 Neighboring gene microRNA mir-12212 Neighboring gene MANSC domain containing 1 Neighboring gene BLOC-1 related complex subunit 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Wnt signaling pathway involved in somitogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor-mediated endocytosis involved in cholesterol transport IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 6
Names
low density lipoprotein receptor-related protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    71734320..71864350 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040647399.2 → XP_040503333.1  low-density lipoprotein receptor-related protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZKE0
    Related
    ENSGALP00010031313.1, ENSGALT00010052398.1
    Conserved Domains (2) summary
    smart00135
    Location:397 → 437
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1274 → 1308
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

  2. XM_015290906.4 → XP_015146392.3  low-density lipoprotein receptor-related protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZKD5, A0A8V0ZKE0
    Related
    ENSGALP00010031257.1, ENSGALT00010052319.1
    Conserved Domains (2) summary
    smart00135
    Location:397 → 437
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1288 → 1322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    72047002..72175917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040660911.2 → XP_040516845.1  low-density lipoprotein receptor-related protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZKE0
    Conserved Domains (2) summary
    smart00135
    Location:397 → 437
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1274 → 1308
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

  2. XM_040660910.2 → XP_040516844.1  low-density lipoprotein receptor-related protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZKD5, A0A8V0ZKE0
    Conserved Domains (2) summary
    smart00135
    Location:397 → 437
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1288 → 1322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
Nucleotide Protein
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