AGT angiotensinogen [Gallus gallus (chicken)] - Gene

Summary

Symbol: AGTprovided by CGNC
Full Name: angiotensinogenprovided by CGNC
Primary source: CGNC:8441
See related: Ensembl:ENSGALG00010007759
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: SERPINA8
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (40135506..40147422, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (40033719..40045617, complement)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ang II role in regulation of cardiovascular function in embryo: Ang II is increasingly effective at raising blood pressure during embryogenesis; amount of Ang II in blood of embryo; limited response to Ang II antagonist
Title: Maturation of the angiotensin II cardiovascular response in the embryonic White Leghorn chicken (Gallus gallus).

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of systemic arterial blood pressure by renin-angiotensin	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: angiotensinogen

Names: Serpin A8; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001396391.2 → NP_001383320.2 angiotensinogen precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000063

UniProtKB/TrEMBL

A0A8V0Y1P3

Related

ENSGALP00010010095.1, ENSGALT00010018438.1

Conserved Domains (1) summary

cl38926
Location:23 → 462

serpin; SERine Proteinase INhibitors (serpin) family
NM_001398463.1 → NP_001385392.1 angiotensinogen precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000063

UniProtKB/TrEMBL

A0A8V0Y1P3

Conserved Domains (1) summary

cl38926
Location:23 → 462

serpin; SERine Proteinase INhibitors (serpin) family
NM_001398464.1 → NP_001385393.1 angiotensinogen precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000063

UniProtKB/TrEMBL

A0A8V0Y1P3

Related

ENSGALP00010010093.1, ENSGALT00010018436.1

Conserved Domains (1) summary

cl38926
Location:23 → 462

serpin; SERine Proteinase INhibitors (serpin) family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

40135506..40147422 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

40033719..40045617 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040667874.2 → XP_040523808.1 angiotensinogen isoform X1

UniProtKB/TrEMBL

A0A8V0XTT7

Conserved Domains (1) summary

cl38926
Location:23 → 462

serpin; SERine Proteinase INhibitors (serpin) family