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PDE4B phosphodiesterase 4B [ Gallus gallus (chicken) ]

Gene ID: 424700, updated on 3-Apr-2024

Summary

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Symbol
PDE4Bprovided by CGNC
Full Name
phosphodiesterase 4Bprovided by CGNC
Primary source
CGNC:8425
See related
Ensembl:ENSGALG00010027081
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (28067173..28211201)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (28079254..28223228)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene leptin receptor overlapping transcript Neighboring gene leptin receptor Neighboring gene uncharacterized LOC107054016 Neighboring gene SH3 domain GRB2 like endophilin interacting protein 1 Neighboring gene Tctex1 domain containing 1 Neighboring gene insulin like 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative metabolic pathway analysis with special reference to nucleotide metabolism-related genes in chicken primordial germ cells. Rengaraj D, et al. Theriogenology, 2013 Jan 1. PMID 23102846
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3',5'-cyclic-AMP phosphodiesterase 4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Names
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
NP_001026462.1
XP_015146515.2
XP_015146516.2
XP_015146517.2
XP_015146518.2
XP_040560625.1
XP_040560626.1
XP_046778823.1
XP_046778824.1
XP_046778825.1
XP_046778826.1
XP_046778827.1
XP_046778828.1
XP_046778829.1
XP_046778830.1
XP_046778831.1
XP_046778833.1
XP_046778834.1
XP_046800477.1
XP_046800478.1
XP_046800480.1
XP_046800481.1
XP_046800482.1
XP_046800483.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031291.2 → NP_001026462.1  3',5'-cyclic-AMP phosphodiesterase 4B

    See identical proteins and their annotated locations for NP_001026462.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ720018
    UniProtKB/TrEMBL
    A0A8V1A1Z1, Q5ZKR6
    Conserved Domains (1) summary
    pfam00233
    Location:232 → 473
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28067173..28211201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291029.4 → XP_015146515.2  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1

    UniProtKB/TrEMBL
    A0A8V1A706
    Conserved Domains (1) summary
    cd00077
    Location:405 → 587
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

  2. XM_046944521.1 → XP_046800477.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1

  3. XM_015291030.4 → XP_015146516.2  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2

    UniProtKB/TrEMBL
    A0A8V1A706, A0A8V1ACF2
    Related
    ENSGALP00010039906.1, ENSGALT00010065640.1
    Conserved Domains (1) summary
    cd00077
    Location:390 → 572
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

  4. XM_015291031.4 → XP_015146517.2  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3

    UniProtKB/TrEMBL
    A0A8V1A706, A0A8V1AEG8
    Related
    ENSGALP00010039904.1, ENSGALT00010065638.1
    Conserved Domains (1) summary
    cd00077
    Location:327 → 509
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

  5. XM_046944526.1 → XP_046800482.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  6. XM_040704691.2 → XP_040560625.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

    UniProtKB/TrEMBL
    A0A8V1A1Z1
    Conserved Domains (1) summary
    cd00077
    Location:186 → 368
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

  7. XM_046944525.1 → XP_046800481.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

    Related
    ENSGALP00010039902.1, ENSGALT00010065636.1

  8. XM_046944522.1 → XP_046800478.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  9. XM_046944527.1 → XP_046800483.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  10. XM_046944524.1 → XP_046800480.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

    Related
    ENSGALP00010039903.1, ENSGALT00010065637.1

  11. XM_040704692.2 → XP_040560626.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

    UniProtKB/TrEMBL
    A0A8V1A1Z1
    Conserved Domains (1) summary
    cd00077
    Location:186 → 368
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

  12. XM_015291032.4 → XP_015146518.2  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X5

    UniProtKB/TrEMBL
    A0A8V1A9J7
    Conserved Domains (1) summary
    cd00077
    Location:172 → 354
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    28079254..28223228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922867.1 → XP_046778823.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X6

  2. XM_046922868.1 → XP_046778824.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2

    UniProtKB/TrEMBL
    A0A8V1ACF2

  3. XM_046922869.1 → XP_046778825.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3

    UniProtKB/TrEMBL
    A0A8V1AEG8

  4. XM_046922875.1 → XP_046778831.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  5. XM_046922872.1 → XP_046778828.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  6. XM_046922870.1 → XP_046778826.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  7. XM_046922874.1 → XP_046778830.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  8. XM_046922877.1 → XP_046778833.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  9. XM_046922873.1 → XP_046778829.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  10. XM_046922871.1 → XP_046778827.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4

  11. XM_046922878.1 → XP_046778834.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X5

Nucleotide Protein Strain
Heading Accession and Version

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